EP0853481A1 - Compositions de traitement d'inflammations contenant certaines prostaglandines et un inhibiteur de cyclo-oxygenase-2 selectif - Google Patents

Compositions de traitement d'inflammations contenant certaines prostaglandines et un inhibiteur de cyclo-oxygenase-2 selectif

Info

Publication number
EP0853481A1
EP0853481A1 EP96930930A EP96930930A EP0853481A1 EP 0853481 A1 EP0853481 A1 EP 0853481A1 EP 96930930 A EP96930930 A EP 96930930A EP 96930930 A EP96930930 A EP 96930930A EP 0853481 A1 EP0853481 A1 EP 0853481A1
Authority
EP
European Patent Office
Prior art keywords
phenyl
furanone
methylsulfonyl
cyclooxygenase
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP96930930A
Other languages
German (de)
English (en)
Inventor
Petpiboon Prasit
Robert N. Young
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Frosst Canada and Co
Original Assignee
Merck Frosst Canada and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9605152.9A external-priority patent/GB9605152D0/en
Application filed by Merck Frosst Canada and Co filed Critical Merck Frosst Canada and Co
Publication of EP0853481A1 publication Critical patent/EP0853481A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins

Abstract

L'invention concerne un procédé de traitement de maladies à médiation cyclo-oxygénase, qui contribue à cicatriser certaines lésions, y compris les ulcères gastriques, par administration simultanée de certaines prostaglandines et d'un inhibiteur sélectif de cyclo-oxygénase-2, ou par administration simultanée d'un agent anti-ulcéreux et d'un inhibiteur sélectif de cyclo-oxygénase-2, conformément à l'invention.
EP96930930A 1995-09-27 1996-09-24 Compositions de traitement d'inflammations contenant certaines prostaglandines et un inhibiteur de cyclo-oxygenase-2 selectif Withdrawn EP0853481A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US441895P 1995-09-27 1995-09-27
US4418P 1995-09-27
GBGB9605152.9A GB9605152D0 (en) 1996-03-12 1996-03-12 Method of treating inflammation
GB9605152 1996-03-12
PCT/CA1996/000638 WO1997011701A1 (fr) 1995-09-27 1996-09-24 Compositions de traitement d'inflammations contenant certaines prostaglandines et un inhibiteur de cyclo-oxygenase-2 selectif

Publications (1)

Publication Number Publication Date
EP0853481A1 true EP0853481A1 (fr) 1998-07-22

Family

ID=26308910

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96930930A Withdrawn EP0853481A1 (fr) 1995-09-27 1996-09-24 Compositions de traitement d'inflammations contenant certaines prostaglandines et un inhibiteur de cyclo-oxygenase-2 selectif

Country Status (4)

Country Link
EP (1) EP0853481A1 (fr)
AU (1) AU6981996A (fr)
CA (1) CA2231550A1 (fr)
WO (1) WO1997011701A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6727238B2 (en) 1998-06-11 2004-04-27 Pfizer Inc. Sulfonylbenzene compounds as anti-inflammatory/analgesic agents
US6294558B1 (en) 1999-05-31 2001-09-25 Pfizer Inc. Sulfonylbenzene compounds as anti-inflammatory/analgesic agents
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
AR038957A1 (es) 2001-08-15 2005-02-02 Pharmacia Corp Terapia de combinacion para el tratamiento del cancer
TW200408621A (en) 2002-04-08 2004-06-01 Glaxo Group Ltd Compounds
GB0225548D0 (en) 2002-11-01 2002-12-11 Glaxo Group Ltd Compounds
EP2344139A1 (fr) 2008-09-09 2011-07-20 AstraZeneca AB Procédé d'administration d'une composition pharmaceutique à un patient en ayant besoin
EA201290026A1 (ru) 2009-06-25 2012-07-30 Астразенека Аб Способ лечения пациента, имеющего риск развития язвы, связанной с приемом нестероидных противовоспалительных средств (nsaid)
BR112014016085A8 (pt) 2011-12-28 2017-07-04 Pozen Inc composições aprimoradas e métodos para distribuição de omeprazol mais ácido acetilsalicílico

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7793791A (en) * 1990-05-03 1991-11-27 G.D. Searle & Co. Pharmaceutical composition for use in treating pain
WO1991016895A1 (fr) * 1990-05-03 1991-11-14 G.D. Searle & Co. Composition pharmaceutique
US5015481A (en) * 1990-05-03 1991-05-14 G. D. Searle & Co. Stabilized pharmaceutical admixture composition
US5474995A (en) * 1993-06-24 1995-12-12 Merck Frosst Canada, Inc. Phenyl heterocycles as cox-2 inhibitors

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9711701A1 *

Also Published As

Publication number Publication date
WO1997011701A1 (fr) 1997-04-03
AU6981996A (en) 1997-04-17
CA2231550A1 (fr) 1997-04-03

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 19980427

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