EP0848619A1 - Bandages orthopediques - Google Patents

Bandages orthopediques

Info

Publication number
EP0848619A1
EP0848619A1 EP96925016A EP96925016A EP0848619A1 EP 0848619 A1 EP0848619 A1 EP 0848619A1 EP 96925016 A EP96925016 A EP 96925016A EP 96925016 A EP96925016 A EP 96925016A EP 0848619 A1 EP0848619 A1 EP 0848619A1
Authority
EP
European Patent Office
Prior art keywords
bandage
bandage according
resin
water
organo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP96925016A
Other languages
German (de)
English (en)
Inventor
Iain Webster
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith and Nephew PLC
Original Assignee
Smith and Nephew PLC
Smith and Nephew Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9515041.3A external-priority patent/GB9515041D0/en
Priority claimed from GBGB9521073.8A external-priority patent/GB9521073D0/en
Priority claimed from GBGB9521074.6A external-priority patent/GB9521074D0/en
Priority claimed from GBGB9603733.8A external-priority patent/GB9603733D0/en
Application filed by Smith and Nephew PLC, Smith and Nephew Inc filed Critical Smith and Nephew PLC
Priority claimed from PCT/GB1996/001754 external-priority patent/WO1997003707A1/fr
Publication of EP0848619A1 publication Critical patent/EP0848619A1/fr
Withdrawn legal-status Critical Current

Links

Definitions

  • Resin based splinting and casting materials find wide use in the immobilisation of limbs, for example the fixation of fractured bones, immobilisation of injured joints and for the support of ligaments and muscles where it is necessary to encase the limb in a partially or completely surrounding rigid form or cast.
  • a suitable material should be easily handleable, with a reasonable setting time to allow sufficient time in the case of casting bandages to mould the bandage about the limb and it should be flexible and free of offensive chemicals which may affect the patient or practitioner applying the material.
  • Splinting and casting materials comprising water activated synthetic polymers in which a cross-linkable prepolymer resin system is coated onto a suitable substrate are well known.
  • the most favoured and commercially developed systems are those based on prepolymers which contain isocyanate functional groups and which in the presence of cold water will cross-link to form urea bridges.
  • the resin systems usually also contain a catalyst to speed up the cross-linking reaction and so that a weight bearing cast may be formed in as shorter time as possible consistent with requirements for moulding and shaping the splint.
  • the isocyanate cross linking reaction is usually an exothermic reaction.
  • the resin chemistry has to be carefully controlled so as to allow the resins to cure in a period of time which is acceptably short and yet not cure under conditions in which so much heat is evolved that the applied cast is uncomfortable to the wearer.
  • a disadvantage of such systems is the relatively high exotherm generated on curing and that there is a perceived health hazard with the use of orthopaedic bandages comprising isocyanate functionalised prepolymers. It is thus desirable to make suitable splinting materials without utilising isocyanate functionalised prepolymers and thus considerable care has to be taken in both the preparation of the splinting or casting material and in its use to ensure that all the isocyanate functionalities are fully reacted.
  • US Patent No. 5,423,735 also describes materials of this type, where the water reactive resin is an alkoxysilane functionalised polyurethane/polyurea resin, produced by reacting isocyanate functionalised precursors.
  • the water reactive resin is an alkoxysilane functionalised polyurethane/polyurea resin, produced by reacting isocyanate functionalised precursors.
  • Such resins potentially have the same problems which may be associated with other prior resins produced from isocyanate functionalised precursors.
  • the present invention seeks to provide an improved orthopaedic casting bandage with a one component resin system which completely avoids the use of free isocyanate groups as the water activated reactive groups, thus eliminating any health hazard which may be associated with the use of materials containing free isocyanate groups.
  • resins comprising ionic linkages avoids the use of isocyanate functionalised prepolymers.
  • an orthopaedic casting bandage as herein defined comprising a flexible substrate carrying a water curable organo-oxy functionalised resin system, characterised in that the resin system comprises at least a prepolymer of the general formula (I)
  • ⁇ are charges of opposite polarities
  • ii) A®, B ⁇ are charged groups of opposite polarities and may be ⁇ NH + , -CC(O)O ' , >NH + 2
  • X comprises a water hydrolysable organo-oxy group based on Ci to Cio hydrocarbon group
  • R 4 , R 6 may be polymeric with pendant
  • the resins employed in the present invention comprise an organo-oxy hydrolysable group.
  • the organo-oxy hydrolysable group is defined as from the group comprising alkoxy [-OR], acyloxy [-OC(O)R] and cyclic alkoxy derivatives based on Ci to Cio hydrocarbon group.
  • the water hydrolysable organo-oxy group is an ethoxy group.
  • M is silicon
  • the organo-oxy groups are hydrolysed to form hydroxy groups which condense together.
  • water curable means that the resin system is capable of hardening to a rigid or semi-rigid structure on exposure to water.
  • reaction may be exemplified by the following formulae illustrating the hydrolysis of an alkoxy silane functionalised resin to give a siloxane [-Si-O-Si-] cross-linked polymer: OR OR i) Resin Si— OR + H 2 0 ⁇ " Resin -Si— OH + ROH
  • the resin of the invention may be precured by the addition of water to cross-link a small percentage of the available silane groups.
  • the advantage gained would be an increase in molecular weight, leading to an increase in viscosity.
  • the resins of the invention may be made by the reaction of carboxylic acid terminated precursors with amine containing a water hydrolysable organo-oxy group or vice versa where the carboxylic acid terminated precursor contains a water hydrolysable organo-oxy group, to produce a salt complex of the following general structures: R— COO H 3 N — R
  • a salt complex is defined as a resin containing ionic linkages.
  • Precursors are defined as groups based on C 1 -C 10 0 hydrocarbon groups, suitably comprising reagents which herein are utilised to prepare the prepolymer of the present invention.
  • the organo-oxy hydrolysis reaction may be catalysed.
  • DBU 1 ,8-diazabicyclo[5.4.0]undec-7-ene
  • potassium fluoride potassium fluoride
  • bismorpholino dialkyl ethers potassium fluoride
  • p-toluene sulphonic acid potassium fluoride
  • Resins as prepared in Examples 1 to 5 were coated onto dry glass fibre bandages by passing the substrate through the resin system followed by passing the coated bandage through a nip roller, adjusted to a suitable pressure for obtaining a coating weight of 50- 60% w/w coating.
  • the resins were optionally mixed with fillers such as Cabo-Sil M5 to improve handling and coating properties.
  • a suitable substrate was a glass fibre bandage.
  • a carboxylic acid terminated alkoxy silane precursor was formed and reacted with Jeffamine EDR148 [0.045mol] to give an alkoxy silane terminated resin.

Landscapes

  • Materials For Medical Uses (AREA)

Abstract

La présente invention concerne un bandage orthopédique moulé comprenant un substrat approprié qui supporte une résine à fonction organo-oxy, durcissable à l'eau, et qui comprend un prépolymère contenant des centres ioniques.
EP96925016A 1995-07-22 1996-07-22 Bandages orthopediques Withdrawn EP0848619A1 (fr)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
GBGB9515041.3A GB9515041D0 (en) 1995-07-22 1995-07-22 Orthopaedic splinting materials
GB9515041 1995-07-22
GBGB9521073.8A GB9521073D0 (en) 1995-10-14 1995-10-14 Splinting materials
GB9521073 1995-10-14
GBGB9521074.6A GB9521074D0 (en) 1995-10-14 1995-10-14 Splinting materials
GB9521074 1995-10-14
GBGB9603733.8A GB9603733D0 (en) 1996-02-22 1996-02-22 Orthopaedic bandages
GB9603733 1996-02-22
PCT/GB1996/001754 WO1997003707A1 (fr) 1995-07-22 1996-07-22 Bandages orthopediques

Publications (1)

Publication Number Publication Date
EP0848619A1 true EP0848619A1 (fr) 1998-06-24

Family

ID=27451312

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96925016A Withdrawn EP0848619A1 (fr) 1995-07-22 1996-07-22 Bandages orthopediques

Country Status (2)

Country Link
EP (1) EP0848619A1 (fr)
AU (1) AU6527396A (fr)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9703707A1 *

Also Published As

Publication number Publication date
AU6527396A (en) 1997-02-18

Similar Documents

Publication Publication Date Title
DE69424042T2 (de) Stützverbände und harze und verfahren zu deren herstellung
EP1030694A1 (fr) Materiau de support orthopedique contenant un silicate
US4655202A (en) Bandages, components thereof and use
AU699059B2 (en) Orthopaedic casting and splinting materials
JPS6137165A (ja) 固定ギプス繃帯用材料
WO1997003707A1 (fr) Bandages orthopediques
EP0094222B1 (fr) Bandages, leurs composants et leur utilisation
AU711469B2 (en) Curable compositions
EP0848619A1 (fr) Bandages orthopediques
EP0847282A1 (fr) Materiels orthopediques
GB2315688A (en) Orthopaedic splinting material
GB2315687A (en) Orthopaedic splinting material
AU5232698A (en) Adhesives
GB2315689A (en) Orthopaedic splinting material
GB2315690A (en) Orthopaedic splinting material
CN1179109A (zh) 矫形外科铸造及夹板材料

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19980129

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): DE FR GB

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: SMITH & NEPHEW PLC

17Q First examination report despatched

Effective date: 20010703

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20011114