EP0825898A1 - Vial holder - Google Patents
Vial holderInfo
- Publication number
- EP0825898A1 EP0825898A1 EP96915848A EP96915848A EP0825898A1 EP 0825898 A1 EP0825898 A1 EP 0825898A1 EP 96915848 A EP96915848 A EP 96915848A EP 96915848 A EP96915848 A EP 96915848A EP 0825898 A1 EP0825898 A1 EP 0825898A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- cavity
- vial
- holder according
- holder
- resilient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/06—Test-tube stands; Test-tube holders
Definitions
- This invention relates to holders for vials containing biological samples which are to be transported on the conveyor line of automated testing equipment.
- Specimens of biological materials such as blood etc. taken from patients for biological testing are often tested using automated testing equipment on which vials containing the specimens are transported on a conveyor belt to various testing instruments located at points adjacent to the conveyor line.
- automated testing equipment on which vials containing the specimens are transported on a conveyor belt to various testing instruments located at points adjacent to the conveyor line.
- Such instruments are generally automated, and mechanical interfaces are provided to transport the vials to the instruments or vice versa.
- Known holders generally comprise a rigid plastics material body with a cavity therein into which a vial may be inserted.
- a problem with known holders is that they can generally hold only one diameter of vial securely, as a cavity suited to one diameter will be too small for larger diameter vials, whilst smaller diameter vials will be a loose fit and will not be held upright.
- EP 047644A and EP 0339775 respectively disclose holders for vials in which a number of respectively downwardly and upwardly pointing resilient fingers extend inwardly into the cavity to bear upon a vial therein.
- US 531676 discloses a holder for vials in which a number of resilient vanes in a cavity hold a vial therein.
- US 5306469 discloses a holder for vials in which a flexible tubular holder is located within the cavity to hold vials. None of these disclosed holders are readily adjustable to hold vials of a wide range of diameters.
- a holder suitable for holding vials in a generally upright orientation for transport on a conveyor line comprises: a body having a cavity therein open at an upwardly facing side of the body, the cavity being of suitable size and shape to receive the lower part of a vial inserted therein, the cavity having bottom and side surfaces, characterised in that in the inwardly facing wall surface of the cavity are one or more recesses, in each recess there being a resilient member extending into the cavity, each member extending into the cavity to a distance sufficient to exert by their resilience a grip upon a vial inserted into the cavity.
- the vials may be the known vials normally used for containing biological samples such as blood etc. on the conveyors of known automated testing equipment, i.e. small glass or plastics material tubes of about 17ml capacity, and ca. 1-2 cm in diameter.
- the conveyor may be of known type, for example a Flex Link - XSTM or Flex Link - XMTM type conveyor.
- the body of the holder can be made of any type of material and by any means.
- the body may be of generally cylindrical shape.
- One of the ends of such a cylinder preferably forms a flat base upon which the holder may be stood whilst on the conveyor, and the other end of the cylinder may also be generally flat and may form the upwardly facing side at which the cavity is open.
- the cavity is preferably a generally cylindrical cavity, but may alternatively be polygonal. In a cylindrical body the axis of such a cavity may be parallel to the longitudinal axis of the body .and the two may be coaxial.
- the width, i.e. the diameter of a cylindrical cavity should be at least the width, e.g.
- the longitudinal depth of the cavity should be less than the length of the vial to be inserted therein but sufficient to allow the vial to be stably retained in the holder.
- vials are labeled with an adhesive machine- readable label, e.g. bearing a bar code, which can be read by sensors arranged along the conveyor to enable detection and identification of the vial, so that it can be handled appropriately for example by automatic machinery responsive to the information on the label.
- the depth of the cavity should be such that such a label is exposed above the upper end of the holder.
- the upper end of the holder may have downwardly extending cut-outs, for example the upper end may be castellated.
- Such constructions enable the label to be easily read without obstruction by parts of the body.
- the said recesses may extend partly through the wall of the body between the cavity and the external surface or may comprise an aperture passing entirely through the body between the cavity .and the external surface.
- Each member may be resiliently movably located in a recess, extending into the cavity.
- the member may be inherently resilient, e.g. made of resilient material of a shape and dimensions such that they can exert their resilience, or additionally or alternatively the members may be resiliently moveably located in the recesses and rendered resilient by means of one or more resilient elements bearing upon these moveable members.
- the resilient element(s) may comprise one or more resilient pads, springs etc. located in the recesses behind the members, or may comprise collars or part collars around the body and the members, and bearing inwardly on the members from behind. Collars or part collars are particularly suitable when the said recesses are apertures which pass entirely through the body between the cavity and the external surface, so that the collar or part collar may surround the body.
- Each recess may be generally in the form of a longitudinal slot, suitably extending for 50% or more of the length of the body, yet being relatively narrow.
- the members suitable for such recess may consequently be relatively long and thin, and therefore capable of extending into the cavity over 50% or more of its length to provide stable gripping of a vial therein.
- the members should be provided with restraint means, e.g. end-stop abutment surfaces to prevent the members falling completely into the cavity.
- the resilient collar or part collar may suitably prevent the member(s) from falling outwardly, or alternatively there may also be end-stops to prevent this too.
- the recess may taper, widening toward the outer surface, and the member(s) may have a corresponding, e.g.
- the recess(s) and member(s) may be respectively provided with engaging guide surfaces to cause the member(s) to move in a guided direction inwardly and outwardly in the recess, for example in a cylindrical cavity the member(s) may be so guided as to move resiliently in a generally radial direction.
- the resilient collar may for example be an elastomer band, or a part collar may be a resilient plastics material or metal circlip around the body and member(s), and may conveniently fit into a guide groove in the body and member(s).
- the collar or part collar may surround the upper part of the member, so that the member may resiliently pivot about its lower part.
- the members may extend radialy inwardly.
- the inward ends of the members function as internal gripping surfaces with less width between opposing ends than the width between the sides of the cavity, and the holder can consequently grip vials with a diameter intermediate between the width between the ends of opposing members and the width of the cavity, thereby enabling the holder to receive vials with a range of diameters between these two widths.
- the body may incorporate additional features to suit it for use on an automated conveyor system, for example a metal base to provide a low centre of gravity, and external grooves or other engagement features to facilitate engagement with handling systems on the conveyor e.g. for presentation to an automated test.
- a metal base to provide a low centre of gravity
- external grooves or other engagement features to facilitate engagement with handling systems on the conveyor e.g. for presentation to an automated test.
- some type of conductive material which provides a means for sensing by conductance, capacitance, electromagnetism or otherwise the travel of a metal probe in the vial may be present.
- This for example provides a means for detecting the presence of a holder on an automatic conveyor line, or for example controlling the depth to which a metal aspiration needle will travel when introduced into the vial as a means for removing a sample for testing.
- a window can be placed in the lower portion of the holder to provide an a window for optical or audio means for sensing the presence of a probe at a particular location in the tube. This sensing means will have an interface with a testing device probe.
- the present invention also provides an automated test apparatus for biological samples which includes holders as described above and a conveyor system suitable to transport said holders.
- the present invention provides a method of automated testing of biological samples in vials including the step of transporting a vial around an automated test operative on a conveyor system, the vial being held in a holder as described above.
- FIG. 1 - A longitudinal sectional view of one embodiment of holder of this invention with an inserted vial.
- Fig. 2 A plan view of the holder of Fig. 1 without the vial.
- Fig. 3 A longitudinal part cutaway sectional view of a further embodiment of holder of this invention.
- FIG. 4 A plan view of the holder of Fig. 3
- FIG. 5 and 6 Views of a resiliently mounted member for the holder of Figs. 3 and 4.
- a holder comprises a hard polyethylene body 1 of generally cylindrical shape.
- Fig. 1 shows a longitudinal section about the Une A-A of Fig. 2.
- body 1 Within body 1 is a cyhndrical cavity 2 of a diameter capable of receiving a vial 3 inserted uprightly therein via the open end of the cavity 2 at an upper end surface 4 of the body.
- the vial 3 rests upon the contoured bottom surface 5 of cavity 2.
- Three recesses 6 at 120° circumferential intervals extend completely through the side surfaces of the body 1 into the cavity 2.
- the members 7 are of a shape and size that allows them to slide smoothly radially inwardly and outwardly in the recess 6, but are restrained from falling into the cavity by end stop abutment surfaces 8, 9.
- a circumferential groove 10 is formed around the body 1 and in the outer surface of the member 7.
- an elastomeric collar 11 which bears resiliently upon the member 7 to urge it inwardly.
- the upper edge of the member 7 is ramp profiled to facilitate insertion of a vial 3, which forces the member 7 outwardly against the resilience of the collar 11. This consequently causes the members 7 to grip the vial 3 resiliently.
- the upper end of the body 1 is castellated with a cut out 12 to facilitate reading of information off a bar code label on a vial 2 inserted therein if the label extends to a position near the bottom of the vial.
- a flat base 13 of the body 1 is formed by a push in friction fit metal insert 14, which enables the holder to be stably seated on a conveyor line, and the position of the holder 1 on a conveyor to be detected by electronic sensors, e.g. responsive to capacitance, conduction or electromagnetism.
- On the vial 3 is a label 15 bearing an optically readable bar code so that information can be read off the vial 3 by a suitable sensor.
- grooves 16 In the outer surface of the body 1 are grooves 16 which facilitate engagement with guide means on a conveyor and/or other handling equipment.
- a further holder of this invention is shown, parts corresponding to Figs. 1 and 2 being numbered correspondingly.
- three recess 17 at 120° circumferential intervals extend completely through the side surfaces of the body 1 into the cavity 2.
- the recesses 17 are open to the upper surface 4 of the body 1 .and have parallel sides as shown in Figs 3 and 4.
- Fig 5 being a side view
- Fig. 6 being a section about the line B -B of Fig. 5.
- the members 18 are of a shape and size that allows them to slide smoothly radially inwardly and outwardly in the recess 17, but are restrained from falling into the cavity by end stop abutment surfaces 19 at their outer end and an abutment foot 20 at their lower end, which abut against corresponding steps 21, 22 in the recess 17.
- a circumferential groove 23 is formed around the body 1 and a corresponding groove 24 is formed in the outer surface of the member 18.
- a corresponding groove 24 is formed in the outer surface of the member 18.
- an elastomeric collar (not shown in Fig 3, corresponding to 11), which bears resiliently upon the member 18 when this is in place in the recess 17 to urge it inwardly.
- the member 18 can therefore slide smoothly and resiUently radially inwardly and outwardly in the recess 17.
- the upper surface 25 of the member 18 is ramp profiled to facilitate insertion of a vial 3 (not shown in Figs 3 - 6), which forces the member 18 outwardly against the resilience of the collar 18. This consequently causes the members 18 to grip the vial 3 resiliently.
- a particular feature of the holder of Figs 3 - 6 is that the inner face 26 of the member 18 is shaped so as to conform and fit flush with the cylindrical shape of the cavity 2 when the member 18 is urged outwardly in the recess 17, and similarly the foot 20 can fit flush into the step 22 in the recess 17. This facilitates the holding by the holder of the invention of vials 3 with an external diameter up to the full internal diameter of the cavity 2.
- the holder of Figs. 5, 6 and 7 is also provided with a metal base 10 (shown non-inserted) analogous to that of Figs 1 - 4, which is a tight friction fit in the lower part of the cavity 2.
- the upper surface 27 of the base 10 is shaped with an upstanding centre portion having a rim 28 around a central conical hollow 29.
- This rim 28 provides a planar surface for a flat-bottomed vial (not shown) to sit stably upon, whilst the conical hollow 29 allows a round bottomed vial (not shown) to sit stably therein.
Landscapes
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Filling Of Jars Or Cans And Processes For Cleaning And Sealing Jars (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
Description
Claims
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9509776.2A GB9509776D0 (en) | 1995-05-15 | 1995-05-15 | Holder |
GB9509776 | 1995-05-15 | ||
GBGB9514913.4A GB9514913D0 (en) | 1995-07-20 | 1995-07-20 | Holder |
GB9514913 | 1995-07-20 | ||
PCT/US1996/007018 WO1996036437A1 (en) | 1995-05-15 | 1996-05-15 | Vial holder |
Publications (3)
Publication Number | Publication Date |
---|---|
EP0825898A1 true EP0825898A1 (en) | 1998-03-04 |
EP0825898A4 EP0825898A4 (en) | 1999-06-16 |
EP0825898B1 EP0825898B1 (en) | 2003-07-09 |
Family
ID=26307028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP96915848A Expired - Lifetime EP0825898B1 (en) | 1995-05-15 | 1996-05-15 | Vial holder |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0825898B1 (en) |
JP (1) | JPH11505920A (en) |
KR (1) | KR100488820B1 (en) |
AT (1) | ATE244606T1 (en) |
AU (1) | AU712957B2 (en) |
CA (1) | CA2220981C (en) |
DE (1) | DE69629025T2 (en) |
DK (1) | DK0825898T3 (en) |
IL (1) | IL118232A (en) |
MX (1) | MX9708869A (en) |
NZ (1) | NZ307989A (en) |
WO (1) | WO1996036437A1 (en) |
Cited By (1)
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EP2327989A4 (en) * | 2008-09-24 | 2016-04-20 | Hitachi High Tech Corp | Specimen rack |
Families Citing this family (65)
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US5769775A (en) * | 1996-07-26 | 1998-06-23 | Labotix Automation Inc. | Automated centrifuge for automatically receiving and balancing samples |
US5941366A (en) * | 1996-09-19 | 1999-08-24 | Labotix Automation, Inc. | Transport system for biospecimens |
JP2005230612A (en) * | 2004-02-17 | 2005-09-02 | Ids:Kk | Test tube holder |
JP4056982B2 (en) | 2004-03-17 | 2008-03-05 | 株式会社アイディエス | Test tube holder |
EP2098296A1 (en) * | 2008-02-25 | 2009-09-09 | F. Hoffmann-La Roche AG | Sample tube rack, sample tube positioning assembly comprising such a rack, and analyzer comprising such an assembly |
JP4677494B2 (en) * | 2009-03-05 | 2011-04-27 | あおい精機株式会社 | Test tube holder |
DE102010028769A1 (en) | 2010-05-07 | 2011-11-10 | Pvt Probenverteiltechnik Gmbh | System for transporting containers between different stations and container carriers |
EP2589968A1 (en) | 2011-11-04 | 2013-05-08 | Roche Diagnostics GmbH | Laboratory sample distribution system, laboratory system and method of operating |
EP2589967A1 (en) | 2011-11-04 | 2013-05-08 | Roche Diagnostics GmbH | Laboratory sample distribution system and corresponding method of operation |
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EP3333576B1 (en) * | 2011-12-28 | 2021-01-27 | Hitachi High-Tech Corporation | Test tube holder |
DE102013210287A1 (en) | 2013-06-04 | 2014-12-04 | Siemens Aktiengesellschaft | Carrier device with bar code reader |
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EP3260867A1 (en) | 2016-06-21 | 2017-12-27 | Roche Diagnostics GmbH | Method of setting a handover position and laboratory automation system |
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EP3537159B1 (en) | 2018-03-07 | 2022-08-31 | Roche Diagnostics GmbH | Method of operating a laboratory sample distribution system, laboratory sample distribution system and laboratory automation system |
EP3540443B1 (en) | 2018-03-16 | 2023-08-30 | Roche Diagnostics GmbH | Laboratory system, laboratory sample distribution system and laboratory automation system |
KR101999604B1 (en) * | 2018-04-26 | 2019-07-15 | 주식회사 수젠텍 | Holder for Specimen Tube |
EP3925911B1 (en) | 2020-06-19 | 2023-05-24 | Roche Diagnostics GmbH | Laboratory sample distribution system and corresponding method of operation |
EP3940388B1 (en) | 2020-07-15 | 2024-04-10 | Roche Diagnostics GmbH | Laboratory sample distribution system and method for operating the same |
US11747356B2 (en) | 2020-12-21 | 2023-09-05 | Roche Diagnostics Operations, Inc. | Support element for a modular transport plane, modular transport plane, and laboratory distribution system |
CN112960277A (en) * | 2021-01-28 | 2021-06-15 | 许昌学院 | Sample storage device for environmental monitoring |
CN113120390A (en) * | 2021-05-12 | 2021-07-16 | 恩大细胞基因工程有限公司 | Method for storing and transporting cells at normal temperature |
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0414644A2 (en) * | 1989-08-25 | 1991-02-27 | Greiner Vibrograf Ag | Chain fashioned holding device having tubes for holding a tubular vessel each |
WO1994000238A1 (en) * | 1992-06-29 | 1994-01-06 | Baxter Diagnostics Inc. | Sample tube carrier |
US5350564A (en) * | 1993-06-28 | 1994-09-27 | Baxter Diagnostics Inc. | Automated chemical analyzer with apparatus and method for conveying and temporary storage of sample tubes |
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US4328185A (en) * | 1980-06-26 | 1982-05-04 | Boehringer Mannheim Corporation | Automated chemical testing apparatus |
US4517851A (en) * | 1983-05-20 | 1985-05-21 | Becton Dickinson And Company | System for controlling septum damage |
US5137693A (en) * | 1990-07-30 | 1992-08-11 | Miles Inc. | Spring biased test tube holder |
-
1996
- 1996-05-13 IL IL11823296A patent/IL118232A/en not_active IP Right Cessation
- 1996-05-15 EP EP96915848A patent/EP0825898B1/en not_active Expired - Lifetime
- 1996-05-15 JP JP8535044A patent/JPH11505920A/en active Pending
- 1996-05-15 WO PCT/US1996/007018 patent/WO1996036437A1/en active IP Right Grant
- 1996-05-15 DK DK96915848T patent/DK0825898T3/en active
- 1996-05-15 NZ NZ307989A patent/NZ307989A/en not_active IP Right Cessation
- 1996-05-15 KR KR1019970708180A patent/KR100488820B1/en not_active IP Right Cessation
- 1996-05-15 AU AU57506/96A patent/AU712957B2/en not_active Expired
- 1996-05-15 AT AT96915848T patent/ATE244606T1/en not_active IP Right Cessation
- 1996-05-15 CA CA002220981A patent/CA2220981C/en not_active Expired - Lifetime
- 1996-05-15 MX MX9708869A patent/MX9708869A/en unknown
- 1996-05-15 DE DE69629025T patent/DE69629025T2/en not_active Expired - Lifetime
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0414644A2 (en) * | 1989-08-25 | 1991-02-27 | Greiner Vibrograf Ag | Chain fashioned holding device having tubes for holding a tubular vessel each |
WO1994000238A1 (en) * | 1992-06-29 | 1994-01-06 | Baxter Diagnostics Inc. | Sample tube carrier |
US5350564A (en) * | 1993-06-28 | 1994-09-27 | Baxter Diagnostics Inc. | Automated chemical analyzer with apparatus and method for conveying and temporary storage of sample tubes |
Non-Patent Citations (1)
Title |
---|
See also references of WO9636437A1 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2327989A4 (en) * | 2008-09-24 | 2016-04-20 | Hitachi High Tech Corp | Specimen rack |
Also Published As
Publication number | Publication date |
---|---|
CA2220981C (en) | 2007-02-20 |
MX9708869A (en) | 1998-03-31 |
DK0825898T3 (en) | 2003-10-06 |
IL118232A (en) | 2001-07-24 |
NZ307989A (en) | 1999-08-30 |
DE69629025D1 (en) | 2003-08-14 |
DE69629025T2 (en) | 2004-04-15 |
KR100488820B1 (en) | 2005-09-08 |
WO1996036437A1 (en) | 1996-11-21 |
AU712957B2 (en) | 1999-11-18 |
EP0825898B1 (en) | 2003-07-09 |
ATE244606T1 (en) | 2003-07-15 |
JPH11505920A (en) | 1999-05-25 |
KR19990014836A (en) | 1999-02-25 |
AU5750696A (en) | 1996-11-29 |
IL118232A0 (en) | 1996-09-12 |
CA2220981A1 (en) | 1996-11-21 |
EP0825898A4 (en) | 1999-06-16 |
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