EP0810866A4 - Verwendung von säureempfindlichen organo-übergangsmetall verbindungen zur behandlung von krebs - Google Patents

Verwendung von säureempfindlichen organo-übergangsmetall verbindungen zur behandlung von krebs

Info

Publication number
EP0810866A4
EP0810866A4 EP96906184A EP96906184A EP0810866A4 EP 0810866 A4 EP0810866 A4 EP 0810866A4 EP 96906184 A EP96906184 A EP 96906184A EP 96906184 A EP96906184 A EP 96906184A EP 0810866 A4 EP0810866 A4 EP 0810866A4
Authority
EP
European Patent Office
Prior art keywords
acid
transition metal
metal compounds
cancer treatment
organo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP96906184A
Other languages
English (en)
French (fr)
Other versions
EP0810866A1 (de
Inventor
Pin Mark Vol
Ilia Levitin
Sergei Osinsky
Laris Bubnovskaya
Marina Tsikalova
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Cancer Research
Cancer Research Institute
Original Assignee
Institute of Cancer Research
Cancer Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institute of Cancer Research, Cancer Research Institute filed Critical Institute of Cancer Research
Publication of EP0810866A1 publication Critical patent/EP0810866A1/de
Publication of EP0810866A4 publication Critical patent/EP0810866A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP96906184A 1995-02-23 1996-01-19 Verwendung von säureempfindlichen organo-übergangsmetall verbindungen zur behandlung von krebs Withdrawn EP0810866A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU95102695A RU2111750C1 (ru) 1995-02-23 1995-02-23 Модификатор для противоопухолевой терапии
RU95102695 1995-02-23
PCT/US1996/000846 WO1996026730A1 (en) 1995-02-23 1996-01-19 Use of acid-sensitive organo- transition metal compounds in cancer treatment

Publications (2)

Publication Number Publication Date
EP0810866A1 EP0810866A1 (de) 1997-12-10
EP0810866A4 true EP0810866A4 (de) 1998-12-09

Family

ID=20165123

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96906184A Withdrawn EP0810866A4 (de) 1995-02-23 1996-01-19 Verwendung von säureempfindlichen organo-übergangsmetall verbindungen zur behandlung von krebs

Country Status (5)

Country Link
EP (1) EP0810866A4 (de)
JP (1) JPH10512279A (de)
CA (1) CA2213344A1 (de)
RU (1) RU2111750C1 (de)
WO (1) WO1996026730A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19932580C2 (de) * 1998-11-30 2003-07-03 Forsch Innovative Medizinische Hyperthermie-Einrichtung
US6444478B1 (en) 1999-08-31 2002-09-03 Micron Technology, Inc. Dielectric films and methods of forming same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5210096A (en) * 1986-05-13 1993-05-11 Chai-Tech Corporation Antiviral compositions and method for their use
US5258403A (en) * 1986-05-13 1993-11-02 Chai-Tech Corporation Metallo-organic salt compounds and pharmaceutical uses thereof
US5348977A (en) * 1991-01-25 1994-09-20 Warner Lambert Company Cobalt complexes as anti-cancer agents

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
CHANDRA ET AL: "antitumor activity of some metal complexes", J INORG BIOCHEM, vol. 48, no. 1, 1992, pages 1 - 14, XP002079622 *
FRANCHETTI ET AL: "antitumor activity of metal(II) chelates of 2,2-bipyridyl-6-carbothioamide", DEV ONCOL, vol. 54, 1988, pages 652 - 656, XP002079624 *
HALL ET AL: "the cytotoxicity of hererocyclic thiosemicarbazones...", ANTICANCER DRUGS, vol. 4, no. 2, 1993, pages 231 - 240, XP002079621 *
KUNCHERIA ET AL: "synthesis characterization and antitumour studies of metal chelates of N-isonicotinoyl-3-methyl-4-(p-hydroxybenzilidene)-2-pyrazolin-5-one", J. OF CHEM. TECHNOLOGY AND BIOTECH., vol. 57, no. 1, 1986, pages 43 - 47, XP002079619 *
MOHAN ET AL: "synthesis characterization and antitumor properties of some metal complexes of 2,6-diacetylpyridine bis(N4-azacyclic thiosemicarbazones)", J INORG BIOCHEM, vol. 34, no. 1, 1988, pages 41 - 54, XP002079623 *
See also references of WO9626730A1 *
SHULMAN ET AL: "action of 1,10-phenanthroline transition metal chelates on P388 mouse lymphocyte leukaemic cells", CHEM BIOL INTERACT, vol. 16, no. 1, 1977, pages 89 - 99, XP002079620 *
SREEKALA ET AL: "synthesis characterization an cytotoxicity or new complexes of cobalt(III), nickel(III) and copper(II) with quinoxaline-2-carboxyaldehyde thiosemicarbazone", SYNTH REACT INORG MET-ORTG CHEM, vol. 24, no. 10, 1994, pages 1773 - 1788, XP002079618 *

Also Published As

Publication number Publication date
WO1996026730A1 (en) 1996-09-06
CA2213344A1 (en) 1996-09-06
JPH10512279A (ja) 1998-11-24
RU95102695A (ru) 1996-11-27
RU2111750C1 (ru) 1998-05-27
EP0810866A1 (de) 1997-12-10

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Legal Events

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