EP0804235A4 - Antibodies to p-selectin and their uses - Google Patents
Antibodies to p-selectin and their usesInfo
- Publication number
- EP0804235A4 EP0804235A4 EP94917301A EP94917301A EP0804235A4 EP 0804235 A4 EP0804235 A4 EP 0804235A4 EP 94917301 A EP94917301 A EP 94917301A EP 94917301 A EP94917301 A EP 94917301A EP 0804235 A4 EP0804235 A4 EP 0804235A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- selectin
- antibodies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/7056—Lectin superfamily, e.g. CD23, CD72
- C07K14/70564—Selectins, e.g. CD62
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
- C07K16/2854—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1993/004274 WO1993021956A1 (en) | 1992-05-05 | 1993-05-04 | Antibodies to p-selectin and their uses |
WOPCT/US93/04274 | 1993-05-04 | ||
US5729293A | 1993-05-05 | 1993-05-05 | |
US57292 | 1993-05-05 | ||
US202047 | 1994-02-25 | ||
US08/202,047 US5800815A (en) | 1903-05-05 | 1994-02-25 | Antibodies to P-selectin and their uses |
PCT/US1994/004935 WO1994025067A1 (en) | 1993-05-04 | 1994-05-04 | Antibodies to p-selectin and their uses |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0804235A1 EP0804235A1 (en) | 1997-11-05 |
EP0804235A4 true EP0804235A4 (en) | 2001-09-19 |
Family
ID=27369213
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP94917301A Withdrawn EP0804235A4 (en) | 1993-05-04 | 1994-05-04 | Antibodies to p-selectin and their uses |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0804235A4 (en) |
FI (1) | FI955261A (en) |
WO (1) | WO1994025067A1 (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU6155896A (en) * | 1995-06-07 | 1996-12-30 | Cytel Corporation | Humanized antibodies to e-selectin |
WO1997000956A1 (en) * | 1995-06-20 | 1997-01-09 | Trustees Of Boston University | Hypoxia-responsive adhesion molecules, specific antibodies, and their uses |
WO1999018442A1 (en) * | 1997-10-07 | 1999-04-15 | Centocor, Inc. | Diagnosis of thrombotic events by detecting p-selectin |
AU2012200852B2 (en) * | 2004-04-13 | 2012-10-18 | F. Hoffmann-La Roche Ag | Anti-P-selectin antibodies |
ES2403055T3 (en) | 2004-04-13 | 2013-05-13 | F. Hoffmann-La Roche Ag | Anti-P-selectin antibodies |
US20110212096A1 (en) | 2006-12-01 | 2011-09-01 | Scott Rollins | Anti-p-selectin antibodies and methods of their use and identification |
US8945565B2 (en) | 2006-12-01 | 2015-02-03 | Selexys Pharmaceuticals Corporation | Methods of treating inflammatory or thrombotic conditions with anti-P-selectin antibodies |
ES2699273T3 (en) | 2006-12-01 | 2019-02-08 | Novartis Ag | Anti-P-selectin antibodies and methods of their use to treat inflammatory diseases |
KR101280704B1 (en) | 2007-10-12 | 2013-07-01 | 에프. 호프만-라 로슈 아게 | Protein expression from multiple nucleic acids |
WO2019025847A1 (en) | 2017-08-04 | 2019-02-07 | Novartis Ag | Treatment regimens |
EP3762424A1 (en) | 2018-03-08 | 2021-01-13 | Novartis AG | Use of an anti-p-selectin antibody |
WO2020247698A1 (en) | 2019-06-07 | 2020-12-10 | Novartis Ag | Use of an anti-p-selectin antibody |
AU2020326490A1 (en) | 2019-08-08 | 2022-03-24 | Novartis Ag | Use of the anti-P-selectin antibody crizanlizumab for treating sickle cell nephropathy and chronic kidney disease associated with sickle cell disease |
WO2022059008A1 (en) * | 2020-09-16 | 2022-03-24 | Ramot At Tel-Aviv University Ltd. | Methods of treating glioblastoma |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993021956A1 (en) * | 1992-05-05 | 1993-11-11 | Cytel Corporation | Antibodies to p-selectin and their uses |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL162181A (en) * | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
ES2097765T3 (en) * | 1989-10-20 | 1997-04-16 | New England Medical Center Inc | A PADGEM INTERMEDIATED CELL LINKING INHIBITION SYSTEM. |
CA2103059C (en) * | 1991-06-14 | 2005-03-22 | Paul J. Carter | Method for making humanized antibodies |
-
1994
- 1994-05-04 EP EP94917301A patent/EP0804235A4/en not_active Withdrawn
- 1994-05-04 WO PCT/US1994/004935 patent/WO1994025067A1/en not_active Application Discontinuation
-
1995
- 1995-11-02 FI FI955261A patent/FI955261A/en not_active Application Discontinuation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993021956A1 (en) * | 1992-05-05 | 1993-11-11 | Cytel Corporation | Antibodies to p-selectin and their uses |
Non-Patent Citations (3)
Title |
---|
CARLOS T M ET AL: "Membrane proteins involved in phagocyte adherence to endothelium.", IMMUNOLOGICAL REVIEWS, (1990 APR) 114 5-28. REF: 122, XP001008136 * |
See also references of WO9425067A1 * |
SHARAR S R ET AL: "P - selectin blockade does not impair leukocyte host defense against bacterial peritonitis and soft tissue infection in rabbits.", JOURNAL OF IMMUNOLOGY, (1993 NOV 1) 151 (9) 4982-8., XP000999480 * |
Also Published As
Publication number | Publication date |
---|---|
FI955261A0 (en) | 1995-11-02 |
WO1994025067A1 (en) | 1994-11-10 |
FI955261A (en) | 1996-01-03 |
EP0804235A1 (en) | 1997-11-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19951129 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: AERES BIOMEDICAL LIMITED |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20010803 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
RIC1 | Information provided on ipc code assigned before grant |
Free format text: 7C 07K 16/28 A, 7C 07K 16/46 B, 7A 61K 39/395 B, 7C 07K 7/06 B, 7C 07K 7/08 B, 7C 12N 5/10 B, 7C 12N 5/16 B, 7C 12N 5/20 B, 7C 12N 7/01 B, 7C 12N 15/00 B, 7C 12N 15/13 B, 7C 12P 21/00 B, 7G 01N 33/53 B |
|
17Q | First examination report despatched |
Effective date: 20020729 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20060907 |