EP0802919A4 - RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS - Google Patents

RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS

Info

Publication number
EP0802919A4
EP0802919A4 EP94923179A EP94923179A EP0802919A4 EP 0802919 A4 EP0802919 A4 EP 0802919A4 EP 94923179 A EP94923179 A EP 94923179A EP 94923179 A EP94923179 A EP 94923179A EP 0802919 A4 EP0802919 A4 EP 0802919A4
Authority
EP
European Patent Office
Prior art keywords
technetium
phosphonate
imaging agents
skeletal imaging
rapidly clearing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94923179A
Other languages
German (de)
French (fr)
Other versions
EP0802919A1 (en
Inventor
Mark A Derosch
Edward A Deutsch
Karen F Deutsch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Inc
Original Assignee
Mallinckrodt Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Medical Inc filed Critical Mallinckrodt Medical Inc
Publication of EP0802919A1 publication Critical patent/EP0802919A1/en
Publication of EP0802919A4 publication Critical patent/EP0802919A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic System
    • C07F13/005—Compounds without a metal-carbon linkage

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP94923179A 1994-06-03 1994-06-03 RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS Withdrawn EP0802919A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BR9408590A BR9408590A (en) 1994-06-03 1994-06-03 Bone imaging agents quickly eliminated from 99m technetium phosphonate
PCT/US1994/006276 WO1995033757A1 (en) 1994-06-03 1994-06-03 RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS

Publications (2)

Publication Number Publication Date
EP0802919A1 EP0802919A1 (en) 1997-10-29
EP0802919A4 true EP0802919A4 (en) 1999-08-18

Family

ID=4060358

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94923179A Withdrawn EP0802919A4 (en) 1994-06-03 1994-06-03 RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS

Country Status (5)

Country Link
EP (1) EP0802919A4 (en)
JP (1) JPH10501218A (en)
AU (1) AU7312694A (en)
BR (1) BR9408590A (en)
WO (1) WO1995033757A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7344702B2 (en) 2004-02-13 2008-03-18 Bristol-Myers Squibb Pharma Company Contrast agents for myocardial perfusion imaging
GB0308408D0 (en) 2003-04-11 2003-05-21 Amersham Plc Microwave activation
US7485283B2 (en) 2004-04-28 2009-02-03 Lantheus Medical Imaging Contrast agents for myocardial perfusion imaging
CA2716354C (en) 2008-02-29 2017-06-13 Lantheus Medical Imaging, Inc. Contrast agents for applications including perfusion imaging
CN102458396B (en) 2009-04-15 2017-05-10 兰休斯医疗成像公司 Stabilization of radiopharmaceutical compositions using ascorbic acid
KR20180055933A (en) 2010-02-08 2018-05-25 랜티우스 메디컬 이메징, 인크. Methods and apparatus for synthesizing imaging agents, and intermediates thereof
AU2013203000B9 (en) 2012-08-10 2017-02-02 Lantheus Medical Imaging, Inc. Compositions, methods, and systems for the synthesis and use of imaging agents
US10620171B2 (en) * 2017-08-31 2020-04-14 Agilent Technologies, Inc. Methods of liquid chromatography for anionic compounds

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0081193A2 (en) * 1981-12-03 1983-06-15 Nihon Medi-Physics Co., Ltd. A stable radioactive diagnostic agent and a non-radioactive carrier therefor
EP0096933A2 (en) * 1982-06-10 1983-12-28 Mallinckrodt, Inc. (a Delaware corporation) Process for making a lyophilized product for use in skeletal imaging
EP0111414A2 (en) * 1982-12-08 1984-06-20 Mallinckrodt, Inc. (a Delaware corporation) Radiographic imaging agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5089249A (en) * 1988-06-10 1992-02-18 Neorx Corporation Conjugates for bone imaging and bone cancer therapy
ATE319482T1 (en) * 1990-07-06 2006-03-15 Mallinckrodt Inc METHOD FOR PREPARING A SOLUTION FROM RADIOACTIVE RHENIUM COMPLEXES

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0081193A2 (en) * 1981-12-03 1983-06-15 Nihon Medi-Physics Co., Ltd. A stable radioactive diagnostic agent and a non-radioactive carrier therefor
EP0096933A2 (en) * 1982-06-10 1983-12-28 Mallinckrodt, Inc. (a Delaware corporation) Process for making a lyophilized product for use in skeletal imaging
EP0111414A2 (en) * 1982-12-08 1984-06-20 Mallinckrodt, Inc. (a Delaware corporation) Radiographic imaging agents

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
COUPAL J. J. ET AL: "Prolonged microwave oven heating is needed for compounding of Tc-99m furifosmin: Preliminary findings", JOURNAL OF NUCLEAR MEDICINE, vol. 38, no. 5, May 1997 (1997-05-01), pages 178P - 179P, XP002105675 *
DE MURPHY C A ET AL: "Radiopharmacokinetic Data for Tc-ABP--A New Radiopharmaceutical for Bone Scanning: Comparison with Tc -MDP", NUCLEAR MEDICINE AND BIOLOGY, vol. 24, no. 1, 1 January 1997 (1997-01-01), pages 27-33, XP004056508 *
MORRISSEY, GARY J. ET AL: "Microwave preparation of technetium-99m-sulfur colloid", J. NUCL. MED. TECHNOL., 1992, 20, 159-62, XP002105674 *
See also references of WO9533757A1 *

Also Published As

Publication number Publication date
EP0802919A1 (en) 1997-10-29
AU7312694A (en) 1996-01-04
JPH10501218A (en) 1998-02-03
WO1995033757A1 (en) 1995-12-14
BR9408590A (en) 1997-08-26

Similar Documents

Publication Publication Date Title
GB9420657D0 (en) Contrast agents
EP0689132A3 (en) Visualizing object-oriented software
GB2288811B (en) Cleansing compositions
ZA954549B (en) Radiolabeled compounds for thrombus imaging
GB2288812B (en) Cleansing compositions
EP1075215A4 (en) Hyaluronan-based imaging agents
ZA956151B (en) 4_phenoxycoumarins as herbicidal agents
GB9424508D0 (en) Cleansing compositions
EP0802919A4 (en) RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS
GB9424521D0 (en) Cleansing compositions
DE69506886D1 (en) Neue acylphosphinoxide
GB9425931D0 (en) Cleansing compositions
GB9415452D0 (en) Cleansing compositions
PL319904A1 (en) Nitrobenzamides useful as antiarrythimic agents
GB9424504D0 (en) Cleansing compositions
HU9603317D0 (en) Rapidly clearing technetium-99m phosphonate skeletal imaging agents
GB2290551B (en) Cleansing compositions
PH30680A (en) Iodinated wetting agents
GB9424008D0 (en) Cleansing compositions
GB9425932D0 (en) Cleansing compositions
GB2295534B (en) Scraper
GB9505468D0 (en) Arylating agents
GB9409021D0 (en) Cleansing compositions
GB9418199D0 (en) Sports shoe stud cleaner (stud scraper)
GB2328928B (en) Parking facilitator

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19961223

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): DE FR GB IT

RIC1 Information provided on ipc code assigned before grant

Free format text: 6C 07F 13/00 A, 6A 61K 51/00 B, 6A 61K 51/04 B

A4 Supplementary search report drawn up and despatched

Effective date: 19990702

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): DE FR GB IT

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: MALLINCKRODT, INC.

17Q First examination report despatched

Effective date: 20000717

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20001128