EP0802919A4 - RASCH AUSGESCHIEDENES TECHNETIUM-99m-PHOSPHONAT FÜR SKELETTABBILDUNG - Google Patents

RASCH AUSGESCHIEDENES TECHNETIUM-99m-PHOSPHONAT FÜR SKELETTABBILDUNG

Info

Publication number
EP0802919A4
EP0802919A4 EP94923179A EP94923179A EP0802919A4 EP 0802919 A4 EP0802919 A4 EP 0802919A4 EP 94923179 A EP94923179 A EP 94923179A EP 94923179 A EP94923179 A EP 94923179A EP 0802919 A4 EP0802919 A4 EP 0802919A4
Authority
EP
European Patent Office
Prior art keywords
technetium
phosphonate
imaging agents
skeletal imaging
rapidly clearing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94923179A
Other languages
English (en)
French (fr)
Other versions
EP0802919A1 (de
Inventor
Mark A Derosch
Edward A Deutsch
Karen F Deutsch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Inc
Original Assignee
Mallinckrodt Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Medical Inc filed Critical Mallinckrodt Medical Inc
Publication of EP0802919A1 publication Critical patent/EP0802919A1/de
Publication of EP0802919A4 publication Critical patent/EP0802919A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP94923179A 1994-06-03 1994-06-03 RASCH AUSGESCHIEDENES TECHNETIUM-99m-PHOSPHONAT FÜR SKELETTABBILDUNG Withdrawn EP0802919A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1994/006276 WO1995033757A1 (en) 1994-06-03 1994-06-03 RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS
BR9408590A BR9408590A (pt) 1994-06-03 1994-06-03 Agentes para imageamento ósseo rapidamente eliminaveis de fosfonato de tecnécio 99m

Publications (2)

Publication Number Publication Date
EP0802919A1 EP0802919A1 (de) 1997-10-29
EP0802919A4 true EP0802919A4 (de) 1999-08-18

Family

ID=4060358

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94923179A Withdrawn EP0802919A4 (de) 1994-06-03 1994-06-03 RASCH AUSGESCHIEDENES TECHNETIUM-99m-PHOSPHONAT FÜR SKELETTABBILDUNG

Country Status (5)

Country Link
EP (1) EP0802919A4 (de)
JP (1) JPH10501218A (de)
AU (1) AU7312694A (de)
BR (1) BR9408590A (de)
WO (1) WO1995033757A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7344702B2 (en) 2004-02-13 2008-03-18 Bristol-Myers Squibb Pharma Company Contrast agents for myocardial perfusion imaging
GB0308408D0 (en) * 2003-04-11 2003-05-21 Amersham Plc Microwave activation
US7485283B2 (en) 2004-04-28 2009-02-03 Lantheus Medical Imaging Contrast agents for myocardial perfusion imaging
ES2767973T3 (es) 2008-02-29 2020-06-19 Lantheus Medical Imaging Inc Agentes de contraste para aplicaciones que comprenden formación de imágenes de perfusión
LT2419096T (lt) 2009-04-15 2020-04-10 Lantheus Medical Imaging, Inc. Radiofarmacinės kompozicijos stabilizavimas naudojant askorbo rūgštį
KR101709372B1 (ko) 2010-02-08 2017-02-22 랜티우스 메디컬 이메징, 인크. 조영제 및 이의 중간체를 합성하는 방법 및 장치
AU2013203000B9 (en) 2012-08-10 2017-02-02 Lantheus Medical Imaging, Inc. Compositions, methods, and systems for the synthesis and use of imaging agents
US10620171B2 (en) * 2017-08-31 2020-04-14 Agilent Technologies, Inc. Methods of liquid chromatography for anionic compounds
CN121532218A (zh) 2023-06-16 2026-02-13 普罗热尼奇制药公司 前列腺特异性膜抗原（psma）放射性标记抑制剂[18f]dcfpyl的改进的合成

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0081193A2 (de) * 1981-12-03 1983-06-15 Nihon Medi-Physics Co., Ltd. Dauerhaftes radioaktives Diagnosemittel und nichtradioaktiver Träger dafür
EP0096933A2 (de) * 1982-06-10 1983-12-28 Mallinckrodt, Inc. (a Delaware corporation) Verfahren zur Herstellung eines lyophilisierten Produktes für die Sichtbarmachung des Skelettes
EP0111414A2 (de) * 1982-12-08 1984-06-20 Mallinckrodt, Inc. (a Delaware corporation) Radiografische Abbildungsmittel
WO1992000758A1 (en) * 1990-07-06 1992-01-23 Mallinckrodt Medical, Inc. Method of preparing a radioactive rhenium complex solution
US5089249A (en) * 1988-06-10 1992-02-18 Neorx Corporation Conjugates for bone imaging and bone cancer therapy

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0081193A2 (de) * 1981-12-03 1983-06-15 Nihon Medi-Physics Co., Ltd. Dauerhaftes radioaktives Diagnosemittel und nichtradioaktiver Träger dafür
EP0096933A2 (de) * 1982-06-10 1983-12-28 Mallinckrodt, Inc. (a Delaware corporation) Verfahren zur Herstellung eines lyophilisierten Produktes für die Sichtbarmachung des Skelettes
EP0111414A2 (de) * 1982-12-08 1984-06-20 Mallinckrodt, Inc. (a Delaware corporation) Radiografische Abbildungsmittel
US5089249A (en) * 1988-06-10 1992-02-18 Neorx Corporation Conjugates for bone imaging and bone cancer therapy
WO1992000758A1 (en) * 1990-07-06 1992-01-23 Mallinckrodt Medical, Inc. Method of preparing a radioactive rhenium complex solution

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
COUPAL J. J. ET AL: "Prolonged microwave oven heating is needed for compounding of Tc-99m furifosmin: Preliminary findings", JOURNAL OF NUCLEAR MEDICINE, vol. 38, no. 5, May 1997 (1997-05-01), pages 178P - 179P, XP002105675 *
DE MURPHY C A ET AL: "Radiopharmacokinetic Data for Tc-ABP--A New Radiopharmaceutical for Bone Scanning: Comparison with Tc -MDP", NUCLEAR MEDICINE AND BIOLOGY, vol. 24, no. 1, 1 January 1997 (1997-01-01), pages 27-33, XP004056508 *
MORRISSEY, GARY J. ET AL: "Microwave preparation of technetium-99m-sulfur colloid", J. NUCL. MED. TECHNOL., 1992, 20, 159-62, XP002105674 *
See also references of WO9533757A1 *
Third World Congress of Nuclear medicine and Biology, 1982, Srivastava et al., "HPLC characterizatiuon of clinically used 99m Tc Bone agents", pp. 1631-1634. *

Also Published As

Publication number Publication date
EP0802919A1 (de) 1997-10-29
WO1995033757A1 (en) 1995-12-14
JPH10501218A (ja) 1998-02-03
BR9408590A (pt) 1997-08-26
AU7312694A (en) 1996-01-04

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Legal Events

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