EP0802919A4 - RASCH AUSGESCHIEDENES TECHNETIUM-99m-PHOSPHONAT FÜR SKELETTABBILDUNG - Google Patents
RASCH AUSGESCHIEDENES TECHNETIUM-99m-PHOSPHONAT FÜR SKELETTABBILDUNGInfo
- Publication number
- EP0802919A4 EP0802919A4 EP94923179A EP94923179A EP0802919A4 EP 0802919 A4 EP0802919 A4 EP 0802919A4 EP 94923179 A EP94923179 A EP 94923179A EP 94923179 A EP94923179 A EP 94923179A EP 0802919 A4 EP0802919 A4 EP 0802919A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- technetium
- phosphonate
- imaging agents
- skeletal imaging
- rapidly clearing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- GKLVYJBZJHMRIY-OUBTZVSYSA-N Technetium-99 Chemical compound [99Tc] GKLVYJBZJHMRIY-OUBTZVSYSA-N 0.000 title 1
- 239000012216 imaging agent Substances 0.000 title 1
- UEZVMMHDMIWARA-UHFFFAOYSA-M phosphonate Chemical compound [O-]P(=O)=O UEZVMMHDMIWARA-UHFFFAOYSA-M 0.000 title 1
- 229940056501 technetium 99m Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dispersion Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1994/006276 WO1995033757A1 (en) | 1994-06-03 | 1994-06-03 | RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS |
BR9408590A BR9408590A (pt) | 1994-06-03 | 1994-06-03 | Agentes para imageamento ósseo rapidamente eliminaveis de fosfonato de tecnécio 99m |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0802919A1 EP0802919A1 (de) | 1997-10-29 |
EP0802919A4 true EP0802919A4 (de) | 1999-08-18 |
Family
ID=4060358
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP94923179A Withdrawn EP0802919A4 (de) | 1994-06-03 | 1994-06-03 | RASCH AUSGESCHIEDENES TECHNETIUM-99m-PHOSPHONAT FÜR SKELETTABBILDUNG |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0802919A4 (de) |
JP (1) | JPH10501218A (de) |
AU (1) | AU7312694A (de) |
BR (1) | BR9408590A (de) |
WO (1) | WO1995033757A1 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7344702B2 (en) | 2004-02-13 | 2008-03-18 | Bristol-Myers Squibb Pharma Company | Contrast agents for myocardial perfusion imaging |
GB0308408D0 (en) * | 2003-04-11 | 2003-05-21 | Amersham Plc | Microwave activation |
US7485283B2 (en) | 2004-04-28 | 2009-02-03 | Lantheus Medical Imaging | Contrast agents for myocardial perfusion imaging |
CA2967254C (en) | 2008-02-29 | 2019-03-26 | Lantheus Medical Imaging, Inc. | Contrast agents for applications including imaging cancer |
EP2419096B1 (de) | 2009-04-15 | 2019-11-13 | Lantheus Medical Imaging, Inc. | Stabilisierung von radiopharmazeutischen zusammensetzungen mit ascorbinsäure |
JP6092628B2 (ja) | 2010-02-08 | 2017-03-08 | ランセウス メディカル イメージング, インコーポレイテッド | 造影剤およびその中間体を合成するための方法および装置 |
AU2013203000B9 (en) | 2012-08-10 | 2017-02-02 | Lantheus Medical Imaging, Inc. | Compositions, methods, and systems for the synthesis and use of imaging agents |
US10620171B2 (en) * | 2017-08-31 | 2020-04-14 | Agilent Technologies, Inc. | Methods of liquid chromatography for anionic compounds |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0081193A2 (de) * | 1981-12-03 | 1983-06-15 | Nihon Medi-Physics Co., Ltd. | Dauerhaftes radioaktives Diagnosemittel und nichtradioaktiver Träger dafür |
EP0096933A2 (de) * | 1982-06-10 | 1983-12-28 | Mallinckrodt, Inc. (a Delaware corporation) | Verfahren zur Herstellung eines lyophilisierten Produktes für die Sichtbarmachung des Skelettes |
EP0111414A2 (de) * | 1982-12-08 | 1984-06-20 | Mallinckrodt, Inc. (a Delaware corporation) | Radiografische Abbildungsmittel |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5089249A (en) * | 1988-06-10 | 1992-02-18 | Neorx Corporation | Conjugates for bone imaging and bone cancer therapy |
DE69133514T2 (de) * | 1990-07-06 | 2006-09-28 | Mallinckrodt, Inc. | Verfahren zur herstellung einer lösung eines radioaktiven rhenium-komplexes |
-
1994
- 1994-06-03 BR BR9408590A patent/BR9408590A/pt not_active Application Discontinuation
- 1994-06-03 EP EP94923179A patent/EP0802919A4/de not_active Withdrawn
- 1994-06-03 WO PCT/US1994/006276 patent/WO1995033757A1/en not_active Application Discontinuation
- 1994-06-03 AU AU73126/94A patent/AU7312694A/en not_active Abandoned
- 1994-06-03 JP JP8500791A patent/JPH10501218A/ja active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0081193A2 (de) * | 1981-12-03 | 1983-06-15 | Nihon Medi-Physics Co., Ltd. | Dauerhaftes radioaktives Diagnosemittel und nichtradioaktiver Träger dafür |
EP0096933A2 (de) * | 1982-06-10 | 1983-12-28 | Mallinckrodt, Inc. (a Delaware corporation) | Verfahren zur Herstellung eines lyophilisierten Produktes für die Sichtbarmachung des Skelettes |
EP0111414A2 (de) * | 1982-12-08 | 1984-06-20 | Mallinckrodt, Inc. (a Delaware corporation) | Radiografische Abbildungsmittel |
Non-Patent Citations (4)
Title |
---|
COUPAL J. J. ET AL: "Prolonged microwave oven heating is needed for compounding of Tc-99m furifosmin: Preliminary findings", JOURNAL OF NUCLEAR MEDICINE, vol. 38, no. 5, May 1997 (1997-05-01), pages 178P - 179P, XP002105675 * |
DE MURPHY C A ET AL: "Radiopharmacokinetic Data for Tc-ABP--A New Radiopharmaceutical for Bone Scanning: Comparison with Tc -MDP", NUCLEAR MEDICINE AND BIOLOGY, vol. 24, no. 1, 1 January 1997 (1997-01-01), pages 27-33, XP004056508 * |
MORRISSEY, GARY J. ET AL: "Microwave preparation of technetium-99m-sulfur colloid", J. NUCL. MED. TECHNOL., 1992, 20, 159-62, XP002105674 * |
See also references of WO9533757A1 * |
Also Published As
Publication number | Publication date |
---|---|
BR9408590A (pt) | 1997-08-26 |
JPH10501218A (ja) | 1998-02-03 |
AU7312694A (en) | 1996-01-04 |
EP0802919A1 (de) | 1997-10-29 |
WO1995033757A1 (en) | 1995-12-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19961223 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): DE FR GB IT |
|
RIC1 | Information provided on ipc code assigned before grant |
Free format text: 6C 07F 13/00 A, 6A 61K 51/00 B, 6A 61K 51/04 B |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19990702 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): DE FR GB IT |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: MALLINCKRODT, INC. |
|
17Q | First examination report despatched |
Effective date: 20000717 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20001128 |