EP0782863A4 - Antibody reagent for detecting dissecting aortic aneurysm and use thereof - Google Patents

Antibody reagent for detecting dissecting aortic aneurysm and use thereof

Info

Publication number
EP0782863A4
EP0782863A4 EP95934876A EP95934876A EP0782863A4 EP 0782863 A4 EP0782863 A4 EP 0782863A4 EP 95934876 A EP95934876 A EP 95934876A EP 95934876 A EP95934876 A EP 95934876A EP 0782863 A4 EP0782863 A4 EP 0782863A4
Authority
EP
European Patent Office
Prior art keywords
aortic aneurysm
detecting
antibody reagent
dissecting aortic
dissecting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP95934876A
Other languages
German (de)
French (fr)
Other versions
EP0782863A1 (en
EP0782863B1 (en
Inventor
Hirohisa Katoh
Ryozo Nagai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamasa Corp
Original Assignee
Yamasa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamasa Corp filed Critical Yamasa Corp
Publication of EP0782863A1 publication Critical patent/EP0782863A1/en
Publication of EP0782863A4 publication Critical patent/EP0782863A4/en
Application granted granted Critical
Publication of EP0782863B1 publication Critical patent/EP0782863B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4712—Muscle proteins, e.g. myosin, actin, protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/329—Diseases of the aorta or its branches, e.g. aneurysms, aortic dissection
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Dissecting aortic aneurysm can be diagnosed readily and rapidly without resort to any particular device by assaying the heavy chain of a smooth muscle myosin present in the blood of a patient by using an antibody against the heavy chain.
EP95934876A 1994-10-25 1995-10-24 Antibody reagent for detecting dissecting aortic aneurysm and use thereof Expired - Lifetime EP0782863B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP284073/94 1994-10-25
JP28407394 1994-10-25
JP28407394 1994-10-25
PCT/JP1995/002180 WO1996012507A1 (en) 1994-10-25 1995-10-24 Antibody reagent for detecting dissecting aortic aneurysm and use thereof

Publications (3)

Publication Number Publication Date
EP0782863A1 EP0782863A1 (en) 1997-07-09
EP0782863A4 true EP0782863A4 (en) 2000-10-04
EP0782863B1 EP0782863B1 (en) 2003-06-11

Family

ID=17673934

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95934876A Expired - Lifetime EP0782863B1 (en) 1994-10-25 1995-10-24 Antibody reagent for detecting dissecting aortic aneurysm and use thereof

Country Status (8)

Country Link
US (1) US5908757A (en)
EP (1) EP0782863B1 (en)
JP (1) JP3499875B2 (en)
AU (1) AU691675B2 (en)
CA (1) CA2202913C (en)
DE (1) DE69531059T2 (en)
FI (1) FI119833B (en)
WO (1) WO1996012507A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4035167B2 (en) 1996-02-19 2008-01-16 ヤマサ醤油株式会社 Diagnostic agent for vascular disorder
JP2011510297A (en) * 2008-01-18 2011-03-31 バトリックス・メディカル・インコーポレイテッド Diagnostic biomarkers for aneurysms
JP6555711B2 (en) * 2015-05-22 2019-08-07 公立大学法人横浜市立大学 Method for determining disease activity of non-dissecting aortic aneurysm
CN108700597A (en) * 2016-02-16 2018-10-23 公立大学法人横浜市立大学 Biomarker in blood for detecting artery sclerosis
US20180192916A1 (en) * 2017-01-10 2018-07-12 General Electric Company Imaging system for diagnosing patient condition

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4943427A (en) * 1984-03-27 1990-07-24 Yamasa Shoyu Kabushiki Kaisha Diagnostic agent for heart disease and use thereof
EP0443511A2 (en) * 1990-02-21 1991-08-28 Mercian Corporation Monoclonal antibodies specific for myosin in the brain
EP0465652A1 (en) * 1989-03-28 1992-01-15 Yamasa Shoyu Kabushiki Kaisha Antibody against heavy chain of smooth muscle myosin
WO1995033476A1 (en) * 1994-06-03 1995-12-14 St. Luke's-Roosevelt Hospital Center A PURIFIED 80 kDa PROTEIN IMPLICATED IN ABDOMINAL AORTIC ANEURYSMS, ANTIBODIES DIRECTED THERETO, AND USES THEREOF

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6028998A (en) * 1983-07-06 1985-02-14 Yamasa Shoyu Co Ltd Monoclonal antibody to heavy chain of myocardial myosine
US5046499A (en) * 1988-06-13 1991-09-10 Centocor, Inc. Method for myocardial infarct risk assessment
JPH02219596A (en) * 1989-12-09 1990-09-03 Yamasa Shoyu Co Ltd Monoclonal antibody against myocardial myosin heavy chain
JP3152706B2 (en) * 1991-11-28 2001-04-03 株式会社東芝 MRI contrast agent having myocardial specificity

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4943427A (en) * 1984-03-27 1990-07-24 Yamasa Shoyu Kabushiki Kaisha Diagnostic agent for heart disease and use thereof
EP0465652A1 (en) * 1989-03-28 1992-01-15 Yamasa Shoyu Kabushiki Kaisha Antibody against heavy chain of smooth muscle myosin
EP0443511A2 (en) * 1990-02-21 1991-08-28 Mercian Corporation Monoclonal antibodies specific for myosin in the brain
WO1995033476A1 (en) * 1994-06-03 1995-12-14 St. Luke's-Roosevelt Hospital Center A PURIFIED 80 kDa PROTEIN IMPLICATED IN ABDOMINAL AORTIC ANEURYSMS, ANTIBODIES DIRECTED THERETO, AND USES THEREOF

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
KATOH H ET AL: "A novel immunoassay of smooth muscle myosin heavy chain in serum", JOURNAL OF IMMUNOLOGICAL METHODS,NL,ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, vol. 185, no. 1, 11 September 1995 (1995-09-11), pages 57 - 63, XP004021154, ISSN: 0022-1759 *
RYOZO NAGAI ET AL: "Identification of Two Types of Smooth Muscle Myosin Heavy Chain Isoforms by cDNA cloning and Immunoblot Analysis", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 264, no. 17, 15 June 1989 (1989-06-15), USA, pages 9734 - 9737, XP002921836 *
See also references of WO9612507A1 *

Also Published As

Publication number Publication date
EP0782863A1 (en) 1997-07-09
EP0782863B1 (en) 2003-06-11
CA2202913C (en) 2004-07-13
DE69531059T2 (en) 2004-05-06
US5908757A (en) 1999-06-01
CA2202913A1 (en) 1996-05-02
FI971754A0 (en) 1997-04-24
JP3499875B2 (en) 2004-02-23
AU3710295A (en) 1996-05-15
FI971754A (en) 1997-04-24
AU691675B2 (en) 1998-05-21
DE69531059D1 (en) 2003-07-17
WO1996012507A1 (en) 1996-05-02
FI119833B (en) 2009-03-31

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