EP0773993A4 - Cellules porcines traitees par genie genetique - Google Patents
Cellules porcines traitees par genie genetiqueInfo
- Publication number
- EP0773993A4 EP0773993A4 EP95928825A EP95928825A EP0773993A4 EP 0773993 A4 EP0773993 A4 EP 0773993A4 EP 95928825 A EP95928825 A EP 95928825A EP 95928825 A EP95928825 A EP 95928825A EP 0773993 A4 EP0773993 A4 EP 0773993A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- genetically engineered
- swine cells
- engineered swine
- cells
- engineered cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 241000282898 Sus scrofa Species 0.000 title 1
- 230000001939 inductive effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2207/00—Modified animals
- A01K2207/15—Humanized animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/108—Swine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/01—Animal expressing industrially exogenous proteins
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
- A01K2267/025—Animal producing cells or organs for transplantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29256594A | 1994-08-19 | 1994-08-19 | |
US292565 | 1994-08-19 | ||
PCT/US1995/010250 WO1996006165A1 (fr) | 1994-08-19 | 1995-08-10 | Cellules porcines traitees par genie genetique |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0773993A1 EP0773993A1 (fr) | 1997-05-21 |
EP0773993A4 true EP0773993A4 (fr) | 2000-07-05 |
Family
ID=23125208
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP95928825A Withdrawn EP0773993A4 (fr) | 1994-08-19 | 1995-08-10 | Cellules porcines traitees par genie genetique |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0773993A4 (fr) |
JP (1) | JPH10507906A (fr) |
AU (1) | AU711183B2 (fr) |
CA (1) | CA2196311A1 (fr) |
WO (1) | WO1996006165A1 (fr) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997006241A1 (fr) * | 1995-08-04 | 1997-02-20 | The General Hospital Corporation | Porc transgenique et cellules de porc possedant des genes hla de l'homme |
EP0979101B1 (fr) | 1996-07-03 | 2010-10-27 | Merial, Inc. | ADENOVIRUS CANIN 2 RECOMBINANT (ACR2) CONTENANT DE l'ADN EXOGENE |
US6011197A (en) | 1997-03-06 | 2000-01-04 | Infigen, Inc. | Method of cloning bovines using reprogrammed non-embryonic bovine cells |
US6224882B1 (en) | 1997-11-07 | 2001-05-01 | Protein Science Corp. | Insect cells or fractions as adjuvant for antigens |
ATE439137T1 (de) | 1997-11-14 | 2009-08-15 | Gen Hospital Corp | Behandlung von hämatologischen störungen |
US6001651A (en) * | 1998-03-20 | 1999-12-14 | Isis Pharmaceuticals Inc. | Antisense modulation of LFA-3 |
US6197294B1 (en) | 1998-10-26 | 2001-03-06 | Neurotech S.A. | Cell surface molecule-induced macrophage activation |
US6700037B2 (en) | 1998-11-24 | 2004-03-02 | Infigen, Inc. | Method of cloning porcine animals |
US6258998B1 (en) | 1998-11-24 | 2001-07-10 | Infigen, Inc. | Method of cloning porcine animals |
PT1534819E (pt) | 2002-08-21 | 2010-03-11 | Revivicor Inc | Animais porcinos carecendo de qualquer expressão de alfa 1,3-galactosiltransferase funcional |
CA2548080A1 (fr) | 2003-11-05 | 2005-05-26 | University Of Pittsburgh | Proteine isogloboside 3 synthase porcine, adnc, organisation genomique, et region regulatrice |
CA2559720A1 (fr) | 2004-03-17 | 2005-09-29 | Revivicor, Inc. | Produits de tissus derives d'animaux depourvus d'expression de l'alpha 1,3 galactosyltransferase fonctionnelle |
EP2711021B1 (fr) | 2008-05-02 | 2016-03-09 | BliNK Therapeutics Limited | Produits et procédés permettant de stimuler une réponse immunitaire |
US20130011424A1 (en) | 2010-03-09 | 2013-01-10 | Timur ARTEMEV | Polyepitope constructs and methods for their preparation and use |
WO2012023033A2 (fr) | 2010-08-18 | 2012-02-23 | Purdue Pharma L.P. | Immunogènes peptidiques améliorés |
WO2016170938A1 (fr) * | 2015-04-20 | 2016-10-27 | 国立大学法人岡山大学 | Modèle animal non humain du cancer et son procédé de construction, cellule souche cancéreuse et son procédé de production |
WO2023240109A1 (fr) | 2022-06-07 | 2023-12-14 | Regeneron Pharmaceuticals, Inc. | Molécules multispécifiques pour moduler l'activité des lymphocytes t, et leurs utilisations |
WO2023240124A1 (fr) | 2022-06-07 | 2023-12-14 | Regeneron Pharmaceuticals, Inc. | Particules virales pseudotypées pour le ciblage de cellules exprimant un tcr |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995020661A1 (fr) * | 1994-01-27 | 1995-08-03 | Bresatec Ltd. | Procedes et substances destines a la prise en charge du rejet hyperaigu suite a une heterogreffe chez l'homme |
WO1995028412A1 (fr) * | 1994-04-13 | 1995-10-26 | Biotransplant, Inc. | PORC NEGATIF POUR L'α(1,3) GALACTOSYLTRANFERASE |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU633958B2 (en) * | 1989-07-25 | 1993-02-11 | Cell Genesys, Inc. | Homologous recombination for universal donor cells and chimeric mammalian hosts |
IN171948B (fr) * | 1989-10-12 | 1993-02-13 | Imutran Ltd |
-
1995
- 1995-08-10 EP EP95928825A patent/EP0773993A4/fr not_active Withdrawn
- 1995-08-10 AU AU32435/95A patent/AU711183B2/en not_active Ceased
- 1995-08-10 CA CA002196311A patent/CA2196311A1/fr not_active Abandoned
- 1995-08-10 WO PCT/US1995/010250 patent/WO1996006165A1/fr not_active Application Discontinuation
- 1995-08-10 JP JP8508145A patent/JPH10507906A/ja active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995020661A1 (fr) * | 1994-01-27 | 1995-08-03 | Bresatec Ltd. | Procedes et substances destines a la prise en charge du rejet hyperaigu suite a une heterogreffe chez l'homme |
WO1995028412A1 (fr) * | 1994-04-13 | 1995-10-26 | Biotransplant, Inc. | PORC NEGATIF POUR L'α(1,3) GALACTOSYLTRANFERASE |
Non-Patent Citations (3)
Title |
---|
DABKOWSKI P L ET AL: "CHARACTERISATION OF A CDNA CLONE ENCODING THE PIG ALPHA1,3 GALACTOSYLTRANSFERASE: IMPLICATIONS FOR XENOTRANSPLANTATION", TRANSPLANTATION PROCEEDINGS, vol. 25, no. 5, October 1993 (1993-10-01), pages 2921, XP000671518 * |
JAMES, A.: "Transplants with transgenic pig organs?", LANCET THE., vol. 342, 3 July 1993 (1993-07-03), LANCET LIMITED. LONDON., GB, pages 45, XP002115010, ISSN: 0140-6736 * |
See also references of WO9606165A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP0773993A1 (fr) | 1997-05-21 |
WO1996006165A1 (fr) | 1996-02-29 |
AU3243595A (en) | 1996-03-14 |
JPH10507906A (ja) | 1998-08-04 |
CA2196311A1 (fr) | 1996-02-29 |
AU711183B2 (en) | 1999-10-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19970227 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
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RIC1 | Information provided on ipc code assigned before grant |
Free format text: 6C 12N 15/00 A, 6A 01K 67/027 B, 6C 07K 14/715 B, 6C 12N 5/10 B |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20000518 |
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AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
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17Q | First examination report despatched |
Effective date: 20010912 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20020123 |