EP0770141A4 - PROTEASE-1 ET 2 D'APOPTOSE DE TYPE ENZYME DE CONVERSION D'INTERLEUKINE-1 -g(b) - Google Patents

PROTEASE-1 ET 2 D'APOPTOSE DE TYPE ENZYME DE CONVERSION D'INTERLEUKINE-1 -g(b)

Info

Publication number
EP0770141A4
EP0770141A4 EP94922009A EP94922009A EP0770141A4 EP 0770141 A4 EP0770141 A4 EP 0770141A4 EP 94922009 A EP94922009 A EP 94922009A EP 94922009 A EP94922009 A EP 94922009A EP 0770141 A4 EP0770141 A4 EP 0770141A4
Authority
EP
European Patent Office
Prior art keywords
interleukin
converting enzyme
apoptosis protease
apoptosis
protease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94922009A
Other languages
German (de)
English (en)
Other versions
EP0770141A1 (fr
Inventor
Wei-Wu He
Craig A Rosen
Gregg A Hastings
Peter L Hudson
Ewen F Kirkness
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Publication of EP0770141A1 publication Critical patent/EP0770141A1/fr
Publication of EP0770141A4 publication Critical patent/EP0770141A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • C12N9/6475—Interleukin 1-beta convertase-like enzymes (3.4.22.10; 3.4.22.36; 3.4.22.63)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EP94922009A 1994-06-23 1994-06-23 PROTEASE-1 ET 2 D'APOPTOSE DE TYPE ENZYME DE CONVERSION D'INTERLEUKINE-1 -g(b) Withdrawn EP0770141A4 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1994/007127 WO1996000297A1 (fr) 1994-06-23 1994-06-23 PROTEASE-1 ET 2 D'APOPTOSE DE TYPE ENZYME DE CONVERSION D'INTERLEUKINE-1 $g(b)

Publications (2)

Publication Number Publication Date
EP0770141A1 EP0770141A1 (fr) 1997-05-02
EP0770141A4 true EP0770141A4 (fr) 1998-03-04

Family

ID=22242697

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94922009A Withdrawn EP0770141A4 (fr) 1994-06-23 1994-06-23 PROTEASE-1 ET 2 D'APOPTOSE DE TYPE ENZYME DE CONVERSION D'INTERLEUKINE-1 -g(b)

Country Status (4)

Country Link
EP (1) EP0770141A4 (fr)
JP (1) JPH10501985A (fr)
AU (1) AU7250494A (fr)
WO (1) WO1996000297A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6087160A (en) * 1993-06-24 2000-07-11 The General Hospital Corporation Programmed cell death genes and proteins
CA2165777A1 (fr) * 1993-06-24 1995-01-05 Junying Yuan Genes et proteines programmes pour la mort des cellules
FR2723378B1 (fr) * 1994-08-02 1996-10-31 Roussel Uclaf Sequence d'adn codant pour une proteine humaine tx apparentee a l'enzyme de conversion de l'interleukine-1beta, proteine tx, procede de production, compositions pharmaceutiques et leurs applications
US6288037B1 (en) 1996-01-29 2001-09-11 Basf Aktiengesellschaft Substrates and inhibitors for cysteine protease ICH-1
WO1997046663A1 (fr) * 1996-05-20 1997-12-11 Smithkline Beecham Corporation Protease-6 de l'apoptose semblable a une enzyme de conversion d'interleukine-1 beta
AU3514197A (en) 1996-07-03 1998-01-21 Genetics Institute Inc. Protease fmh-1, an ice/ced-like protease
US6512104B1 (en) 1996-10-01 2003-01-28 Amgen Inc. Interleukin-1β converting enzyme like cysteine protease
EP0842665A3 (fr) * 1996-11-14 2002-12-18 Smithkline Beecham Corporation Protéases d'apoptose de type enzyme de conversion d'interleukine-1-bèta et leurs agonistes
US5929042A (en) * 1997-03-03 1999-07-27 The Trustees Of Columbia University In The City Of New York Antisense compounds which prevent cell death and uses thereof
US7223856B2 (en) 1997-03-03 2007-05-29 The Trustees Of Columbia University In The City Of New York Antisense compounds which prevent cell death and uses thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991015577A1 (fr) * 1990-04-04 1991-10-17 Black, Roy, A. INTERLEUKIN 1'beta' PROTEASE
WO1995000160A1 (fr) * 1993-06-24 1995-01-05 The General Hospital Corporation Genes regulateurs de la mort cellulaire programmee et proteines
WO1995027793A1 (fr) * 1994-04-08 1995-10-19 Merck Frosst Canada Inc. ADN CODANT UN PRECURSEUR DE LA CYSTEINE PROTEINASE II (ICErel-II) APPARENTEE A L'ENZYME DE CONVERSION DE L'INTERLEUKINE-1$g(b)

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991015577A1 (fr) * 1990-04-04 1991-10-17 Black, Roy, A. INTERLEUKIN 1'beta' PROTEASE
WO1995000160A1 (fr) * 1993-06-24 1995-01-05 The General Hospital Corporation Genes regulateurs de la mort cellulaire programmee et proteines
WO1995027793A1 (fr) * 1994-04-08 1995-10-19 Merck Frosst Canada Inc. ADN CODANT UN PRECURSEUR DE LA CYSTEINE PROTEINASE II (ICErel-II) APPARENTEE A L'ENZYME DE CONVERSION DE L'INTERLEUKINE-1$g(b)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9600297A1 *

Also Published As

Publication number Publication date
JPH10501985A (ja) 1998-02-24
WO1996000297A1 (fr) 1996-01-04
AU7250494A (en) 1996-01-19
EP0770141A1 (fr) 1997-05-02

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 19970120

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Ipc: C12N 15/57

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Effective date: 19980119

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18D Application deemed to be withdrawn

Effective date: 20000530