EP0757558A4 - Methode zum auffinden von agentien, die eine entzündliche hautreaktion modulieren - Google Patents
Methode zum auffinden von agentien, die eine entzündliche hautreaktion modulierenInfo
- Publication number
- EP0757558A4 EP0757558A4 EP95917009A EP95917009A EP0757558A4 EP 0757558 A4 EP0757558 A4 EP 0757558A4 EP 95917009 A EP95917009 A EP 95917009A EP 95917009 A EP95917009 A EP 95917009A EP 0757558 A4 EP0757558 A4 EP 0757558A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- integumental
- screening methods
- modulating agents
- inflammation modulating
- inflammation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Urology & Nephrology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Pulmonology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Dermatology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99201333A EP0937460A3 (de) | 1994-04-12 | 1995-04-11 | Verwendung eines Mittels gegen Durchfall für die Zubereitung eines Medikaments für die Behandlung von Entzündungen |
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22599194A | 1994-04-12 | 1994-04-12 | |
US225991 | 1994-04-12 | ||
US27128794A | 1994-07-06 | 1994-07-06 | |
US271287 | 1994-07-06 | ||
US40023495A | 1995-03-03 | 1995-03-03 | |
US400234 | 1995-03-03 | ||
PCT/US1995/004677 WO1995027510A1 (en) | 1994-04-12 | 1995-04-11 | Screening methods for integumental inflammation modulating agents |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP99201333A Division EP0937460A3 (de) | 1994-04-12 | 1995-04-11 | Verwendung eines Mittels gegen Durchfall für die Zubereitung eines Medikaments für die Behandlung von Entzündungen |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0757558A1 EP0757558A1 (de) | 1997-02-12 |
EP0757558A4 true EP0757558A4 (de) | 1999-06-16 |
Family
ID=27397548
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP95917009A Withdrawn EP0757558A4 (de) | 1994-04-12 | 1995-04-11 | Methode zum auffinden von agentien, die eine entzündliche hautreaktion modulieren |
EP99201333A Withdrawn EP0937460A3 (de) | 1994-04-12 | 1995-04-11 | Verwendung eines Mittels gegen Durchfall für die Zubereitung eines Medikaments für die Behandlung von Entzündungen |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP99201333A Withdrawn EP0937460A3 (de) | 1994-04-12 | 1995-04-11 | Verwendung eines Mittels gegen Durchfall für die Zubereitung eines Medikaments für die Behandlung von Entzündungen |
Country Status (4)
Country | Link |
---|---|
EP (2) | EP0757558A4 (de) |
JP (1) | JPH10500669A (de) |
AU (1) | AU2385795A (de) |
WO (1) | WO1995027510A1 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0754046A1 (de) * | 1994-04-04 | 1997-01-22 | FREEMAN, William R. | Verwendung der phosphonylmethoxyalkyl-nukleoside zur behandlung des erhöhten innenaugendrucks |
ATE199390T1 (de) * | 1995-12-21 | 2001-03-15 | Nestle Sa | Unsterbliche humane hautzell-linien und serumfreies medium für ihre herstellung |
US5798093A (en) * | 1997-03-14 | 1998-08-25 | Adolor Corporation | Spray formulations of antihyperalgesic opiates and method of treating topical hyperalgesic conditions and pruritus therewith |
US5849762A (en) * | 1997-07-14 | 1998-12-15 | Adolor Corporation | Peripherally acting anti-pruritic opiates |
US6353004B1 (en) | 1997-07-14 | 2002-03-05 | Adolor Coporation | Peripherally acting anti-pruritic opiates |
AUPP646498A0 (en) * | 1998-10-12 | 1998-11-05 | Australian National University, The | A method of modulating ion channel functional activity |
DE19948126A1 (de) * | 1999-10-06 | 2001-04-12 | Max Delbrueck Centrum | Pharmazeutisches Mittel zur Behandlung von Kachexie und/oder kardiogenem Schock |
CA2416152A1 (en) * | 2000-07-27 | 2002-02-07 | Pharmacia Corporation | Aldosterone blocker therapy to prevent or treat inflammation-related disorders |
US6697668B2 (en) * | 2001-01-25 | 2004-02-24 | Iomed, Inc. | Ocular iontophoretic device and method for using the same |
PL371436A1 (en) * | 2002-01-30 | 2005-06-13 | Pharmacia Corporation | Aldosterone antagonist and non-steroidal anti-inflammatory agent combination therapy to prevent or treat cardiovascular disorders |
ZA200702216B (en) * | 2004-08-18 | 2008-11-26 | Ace Aps | Cosmetic and pharmaceutical compositions comprising ACE inhibitors and/or angiotensin II receptor antagonists |
US8618113B2 (en) | 2006-07-14 | 2013-12-31 | Medical Research Council | Treatment for demyelinating disease |
JP2008222603A (ja) * | 2007-03-09 | 2008-09-25 | Institute Of Physical & Chemical Research | 神経変性疾患の予防・治療剤 |
US20220204456A1 (en) * | 2019-04-30 | 2022-06-30 | Generos Biopharma Ltd. | Compound for treating autoimmune skin diseases caused by inflammation, and use thereof |
WO2021211979A1 (en) * | 2020-04-17 | 2021-10-21 | Biolectrics Llc | Systems and methods for oral iontophoresis |
WO2022253910A1 (en) * | 2021-06-02 | 2022-12-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | A new method to treat an inflammatory skin disease |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991002497A1 (en) * | 1989-08-21 | 1991-03-07 | Beth Israel Hospital Association | Topical nifedipine for cutaneous, ocular, mucosal hypersensitivity, inflammatory and hyperproliferative conditions |
DD297062A5 (de) * | 1990-08-23 | 1992-01-02 | Tks Optimum Gmbh,Dd | Verfahren zur herstellung eines neuartigen topischen dermatikums mit antientzuendlicher wirkung |
US5202130A (en) * | 1989-08-31 | 1993-04-13 | The Johns Hopkins University | Suppression of eczematous dermatitis by calcium transport inhibition |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4384000A (en) * | 1980-08-07 | 1983-05-17 | Lanier Earl W | Method for treatment of various dermatological conditions |
GB8806224D0 (en) * | 1988-03-16 | 1988-04-13 | Johnson Matthey Plc | Platinum chemotherapeutic product |
US5116847A (en) * | 1991-01-25 | 1992-05-26 | The Procter & Gamble Company | Use of loperamide and related compounds for treatment of respiratory disease symptoms |
-
1995
- 1995-04-11 EP EP95917009A patent/EP0757558A4/de not_active Withdrawn
- 1995-04-11 AU AU23857/95A patent/AU2385795A/en not_active Abandoned
- 1995-04-11 JP JP7526541A patent/JPH10500669A/ja not_active Ceased
- 1995-04-11 EP EP99201333A patent/EP0937460A3/de not_active Withdrawn
- 1995-04-11 WO PCT/US1995/004677 patent/WO1995027510A1/en not_active Application Discontinuation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991002497A1 (en) * | 1989-08-21 | 1991-03-07 | Beth Israel Hospital Association | Topical nifedipine for cutaneous, ocular, mucosal hypersensitivity, inflammatory and hyperproliferative conditions |
US5202130A (en) * | 1989-08-31 | 1993-04-13 | The Johns Hopkins University | Suppression of eczematous dermatitis by calcium transport inhibition |
DD297062A5 (de) * | 1990-08-23 | 1992-01-02 | Tks Optimum Gmbh,Dd | Verfahren zur herstellung eines neuartigen topischen dermatikums mit antientzuendlicher wirkung |
Non-Patent Citations (4)
Title |
---|
EVANS CH ET AL.: "Inhibition, by lanthanides, of neutral proteinases secreted by human rheumatoid synovium", EUR.J.BIOCHEM., vol. 151, 1985, pages 29 - 32, XP002098132 * |
GANGAROSA L P ET AL: "CONDUCTIVITY OF DRUGS USED FOR IONTOPHORESIS", JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 67, no. 10, October 1978 (1978-10-01), pages 1439 - 1443, XP002055803 * |
J.INVESTIG.DERMATOL., vol. 93, no. 3, 1989, pages 322 - 326, XP002098133 * |
See also references of WO9527510A1 * |
Also Published As
Publication number | Publication date |
---|---|
AU2385795A (en) | 1995-10-30 |
EP0757558A1 (de) | 1997-02-12 |
EP0937460A2 (de) | 1999-08-25 |
EP0937460A3 (de) | 2000-04-05 |
JPH10500669A (ja) | 1998-01-20 |
WO1995027510A1 (en) | 1995-10-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
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