EP0753006A4 - PROTEINES Vpr ET Vpx DU VIH - Google Patents

PROTEINES Vpr ET Vpx DU VIH

Info

Publication number
EP0753006A4
EP0753006A4 EP95912976A EP95912976A EP0753006A4 EP 0753006 A4 EP0753006 A4 EP 0753006A4 EP 95912976 A EP95912976 A EP 95912976A EP 95912976 A EP95912976 A EP 95912976A EP 0753006 A4 EP0753006 A4 EP 0753006A4
Authority
EP
European Patent Office
Prior art keywords
vpr
hiv
vpx proteins
vpx
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95912976A
Other languages
German (de)
English (en)
Other versions
EP0753006A1 (fr
Inventor
Ahmed A Azad
Ian G Macreadie
Chinniah Arunagiri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomolecular Research Institute Ltd
Original Assignee
Biomolecular Research Institute Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AUPM4697A external-priority patent/AUPM469794A0/en
Priority claimed from AUPN0902A external-priority patent/AUPN090295A0/en
Application filed by Biomolecular Research Institute Ltd filed Critical Biomolecular Research Institute Ltd
Publication of EP0753006A1 publication Critical patent/EP0753006A1/fr
Publication of EP0753006A4 publication Critical patent/EP0753006A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP95912976A 1994-03-25 1995-03-24 PROTEINES Vpr ET Vpx DU VIH Withdrawn EP0753006A4 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AUPM4697A AUPM469794A0 (en) 1994-03-25 1994-03-25 Therapeutic compounds
AUPM4697/94 1994-03-25
AUPN0902A AUPN090295A0 (en) 1995-02-03 1995-02-03 Therapeutic compounds
AUPN0902/95 1995-02-03
PCT/AU1995/000169 WO1995026361A1 (fr) 1994-03-25 1995-03-24 PROTEINES Vpr ET Vpx DU VIH

Publications (2)

Publication Number Publication Date
EP0753006A1 EP0753006A1 (fr) 1997-01-15
EP0753006A4 true EP0753006A4 (fr) 1999-04-14

Family

ID=25644649

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95912976A Withdrawn EP0753006A4 (fr) 1994-03-25 1995-03-24 PROTEINES Vpr ET Vpx DU VIH

Country Status (4)

Country Link
EP (1) EP0753006A4 (fr)
JP (1) JPH09511395A (fr)
CA (1) CA2186398A1 (fr)
WO (1) WO1995026361A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5780220A (en) * 1994-05-19 1998-07-14 Trustees Of The University Of Pennsylvania Methods and compositions for inhibiting HIV replication
ATE408015T1 (de) * 1995-04-14 2008-09-15 Univ Alabama Res Found Transfer system basierend auf einem fusionsprotein und seine anwendungen.
US6087486A (en) * 1996-01-29 2000-07-11 The Trustees Of The University Of Pennsylvania Nucleotide sequences encoding vpr receptor protein
AUPO258196A0 (en) * 1996-09-27 1996-10-17 Australian National University, The Method for determining ion channel activity of a substance
AU6435598A (en) * 1997-02-11 1998-08-26 Regents Of The University Of California, The Identifying agents for treating lentiviral infection
US7622300B2 (en) 1998-06-03 2009-11-24 Kappes John C Trans-lentiviral vector particles and transduction of eukaryotic cells therewith
US6555342B1 (en) 1998-06-03 2003-04-29 Uab Research Foundation Fusion protein delivery system and uses thereof
DE19908752A1 (de) * 1999-02-19 2000-08-31 Ulrich Schubert Synthetische Peptide des regulatorischen Virusproteins R (Vpr) des Humanen Immundefizienzvirus Typ 1
DE19908766C2 (de) * 1999-02-19 2001-02-15 Ulrich Schubert Verwendung synthetischer Vpr-Peptide des Humanen Immundefizienzvirus Typ 1 (HIV-1) zur Entwicklung von therapeutischen und diagnostischen Reagenzien
WO2000049038A2 (fr) 1999-02-19 2000-08-24 Ulrich Schubert Peptides de synthese de la proteine virale regulatrice (vpr) du virus de l'immunodeficience humaine de type 1 (vih1) et leur utilisation
US6984486B1 (en) 1999-02-19 2006-01-10 J. David Gladstone Institutes Synthetic peptide of regulatory virus protein R (VPR) of human immunodeficiency virus type 1 (HIV-1) and the utilization thereof
US6664040B2 (en) 2000-05-23 2003-12-16 The Regents Of The University Of California Compositions and methods for delivery of a molecule into a cell
WO2003037264A2 (fr) * 2001-10-29 2003-05-08 Genzyme Corporation Composes therapeutiques anti-vih (vpr)
JPWO2005032561A1 (ja) * 2003-10-03 2006-12-14 独立行政法人理化学研究所 ＨＩＶ−Ｖｐｒの機能に関する発明
FR2868841B1 (fr) * 2004-04-09 2006-07-14 Bioalliance Pharma Sa Methode d'identification de composes actifs sur la replication du virus hiv
WO2005103654A2 (fr) * 2004-04-09 2005-11-03 Bioalliance Pharma Methode d’identification de composes actifs sur la replication du virus hiv.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990015875A1 (fr) * 1989-06-02 1990-12-27 Dana Farber Cancer Institute Proteine presentant une propriete de transactivation, vecteurs exprimant cette proteine, lignees cellulaires, et leurs utilisations
WO1994019456A1 (fr) * 1993-02-19 1994-09-01 Weiner David B Activite et fonction de la proteine virale r

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0491930B1 (fr) * 1990-07-12 1997-01-15 The President And Fellows Of Harvard College Vaccins prepares a partir d'un lentivirus de primate
US6107062A (en) * 1992-07-30 2000-08-22 Inpax, Inc. Antisense viruses and antisense-ribozyme viruses
AU5848794A (en) * 1993-02-05 1994-08-29 Regents Of The University Of California, The Multiple-gene mutants of human immunodeficiency virus (hiv) for vaccine use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990015875A1 (fr) * 1989-06-02 1990-12-27 Dana Farber Cancer Institute Proteine presentant une propriete de transactivation, vecteurs exprimant cette proteine, lignees cellulaires, et leurs utilisations
WO1994019456A1 (fr) * 1993-02-19 1994-09-01 Weiner David B Activite et fonction de la proteine virale r

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
COHEN E A ET AL.: "Identification of HIV-1 vpr product and function", JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, vol. 3, no. 1, 1990, new york, pages 11 - 18, XP002085625 *
See also references of WO9526361A1 *
ZHANG S ET AL: "Direct binding to nucleic acids by Vpr of human immunodeficiency virus type 1", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES, vol. 212, no. 2, 8 June 1998 (1998-06-08), pages 157-166, XP004122917 *

Also Published As

Publication number Publication date
JPH09511395A (ja) 1997-11-18
WO1995026361A1 (fr) 1995-10-05
CA2186398A1 (fr) 1995-10-05
EP0753006A1 (fr) 1997-01-15

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 19960916

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Effective date: 20021031