EP0746610A4 - Klonierung von säugetieren durch nukleäre transplantation embryonaler stammzellen und esc - Google Patents

Klonierung von säugetieren durch nukleäre transplantation embryonaler stammzellen und esc

Info

Publication number
EP0746610A4
EP0746610A4 EP93923115A EP93923115A EP0746610A4 EP 0746610 A4 EP0746610 A4 EP 0746610A4 EP 93923115 A EP93923115 A EP 93923115A EP 93923115 A EP93923115 A EP 93923115A EP 0746610 A4 EP0746610 A4 EP 0746610A4
Authority
EP
European Patent Office
Prior art keywords
esc
stem cell
embryonic stem
nuclear transplantation
mammalian cloning
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93923115A
Other languages
English (en)
French (fr)
Other versions
EP0746610A1 (de
Inventor
Michael A Reed
Thomas Edward Edison Wagner
Jacek A Modlinski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ohio University
Ohio State University
Original Assignee
Ohio University
Ohio State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ohio University, Ohio State University filed Critical Ohio University
Publication of EP0746610A1 publication Critical patent/EP0746610A1/de
Publication of EP0746610A4 publication Critical patent/EP0746610A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
    • A01K67/027—New breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
EP93923115A 1993-09-22 1993-09-22 Klonierung von säugetieren durch nukleäre transplantation embryonaler stammzellen und esc Withdrawn EP0746610A4 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1993/008878 WO1995008625A1 (en) 1993-09-22 1993-09-22 Mammalian cloning by embryonic stem cell (esc) nuclear transplantation and esc

Publications (2)

Publication Number Publication Date
EP0746610A1 EP0746610A1 (de) 1996-12-11
EP0746610A4 true EP0746610A4 (de) 1997-11-26

Family

ID=22236975

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93923115A Withdrawn EP0746610A4 (de) 1993-09-22 1993-09-22 Klonierung von säugetieren durch nukleäre transplantation embryonaler stammzellen und esc

Country Status (3)

Country Link
EP (1) EP0746610A4 (de)
AU (1) AU5290793A (de)
WO (1) WO1995008625A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5523226A (en) * 1993-05-14 1996-06-04 Biotechnology Research And Development Corp. Transgenic swine compositions and methods
US5907080A (en) * 1995-11-30 1999-05-25 Nexia Biotechnologies, Inc. Method for development of transgenic dwarf goats
AUPP294898A0 (en) * 1998-04-15 1998-05-07 Monash University Method of nuclear transfer
CA2634294A1 (en) 2000-08-03 2002-02-14 Therapeutic Human Polyclonals, Inc. Production of humanized antibodies in transgenic animals
EP2064325B1 (de) 2006-09-01 2011-12-07 Therapeutic Human Polyclonals, Inc. Erhöhte expression von humanem oder humanisiertem immunglobulin bei nicht-humanen transgenen tieren

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4873191A (en) * 1981-06-12 1989-10-10 Ohio University Genetic transformation of zygotes
CH666850A5 (de) * 1983-06-30 1988-08-31 Inst Biokhim I Fiziol Mikroorg Verfahren zur durchfuehrung von mikrooperationen an zellen und einrichtung zu dessen verwirklichung.
US4806476A (en) * 1983-09-08 1989-02-21 Lovelace Medical Foundation Efficient cell fusion process
US4664097A (en) * 1984-05-09 1987-05-12 The Wistar Institute Of Anatomy & Biology Nuclear transplantation in the mammalian embryo by microsurgery and cell fusion
US5032407A (en) * 1987-01-16 1991-07-16 Ohio University Edison Animal Biotechnology Center Gene transfer using transformed, neodetermined, embryonic cells
US5057420A (en) * 1987-06-05 1991-10-15 Granada Biosciences, Inc. Bovine nuclear transplantation

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
FIRST, N.L. & PRATHER, R.C.: "Genomic potential in mammals", DIFFERENTIATION, vol. 48, no. 1, September 1991 (1991-09-01), pages 1 - 8, XP000607074 *
FIRST, N.L. ET AL.: "Systems for production of calves from cultured bovine embryonic cells", REPRODUCTION , FERTILITY AND DEVELOPMENT, vol. 6, no. 5, 1 January 1994 (1994-01-01), pages 553 - 562, XP000603897 *
Meeting "Molecular Biology and Embryo Technology in Animal Breeding" September 27-30, 1992 Jastrzebiec & Popielno, Poland *
Meeting: "Molecular Biology and Embryo Technology in Animal Breeding" September 27-30, 1992 Jastrzbiec & Popielno, Poland *
MODLINSKI, J.A. ET AL.: "Developmental capacity of mouse embryonic stem cells and embryonic stem cell nuclei", ANIMAL SCIENCE PAPERS AND REPORTS, vol. 11, no. 2, 1 January 1993 (1993-01-01), pages 135 - 140, XP000603974 *
REED, M.A. ET AL.: "Progress in establishing embryonic stem cells in cattle", ANIMAL SCIENCE PAPERS AND REPORTS, vol. 11, no. 2, 1 January 1993 (1993-01-01), pages 141 - 146, XP000603973 *
SEAMARK, R.F.: "Embryo multiplication- Present status of nuclear transfer and embryonic stem cell technology in livestock", MEDE FAC LANDBOUW UNIV GENT, vol. 57, no. 4 part b, 1992, pages 1837 - 1842, XP000603947 *
See also references of WO9508625A1 *
SIMS, M. ET FIRST, N.L.: "Production of calves by transfer of nuclei from cultured inner cell mass cells", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 91, no. 13, 21 September 1994 (1994-09-21), WASHINGTON US, pages 6143 - 6147, XP000604993 *

Also Published As

Publication number Publication date
WO1995008625A1 (en) 1995-03-30
EP0746610A1 (de) 1996-12-11
AU5290793A (en) 1995-04-10

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