EP0737314A4 - Nouvelles utilisations de produits de recombinaison de recepteurs de gal4 - Google Patents

Nouvelles utilisations de produits de recombinaison de recepteurs de gal4

Info

Publication number
EP0737314A4
EP0737314A4 EP95905946A EP95905946A EP0737314A4 EP 0737314 A4 EP0737314 A4 EP 0737314A4 EP 95905946 A EP95905946 A EP 95905946A EP 95905946 A EP95905946 A EP 95905946A EP 0737314 A4 EP0737314 A4 EP 0737314A4
Authority
EP
European Patent Office
Prior art keywords
gal4
novel uses
receptor constructs
constructs
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP95905946A
Other languages
German (de)
English (en)
Other versions
EP0737314A1 (fr
Inventor
Ronald M Evans
Kazuhiko Umesono
Bruce Blumberg
Pundi N Rangarajan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Salk Institute for Biological Studies
Original Assignee
Salk Institute for Biological Studies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salk Institute for Biological Studies filed Critical Salk Institute for Biological Studies
Priority to EP96111192A priority Critical patent/EP0743520A3/fr
Publication of EP0737314A1 publication Critical patent/EP0737314A1/fr
Publication of EP0737314A4 publication Critical patent/EP0737314A4/fr
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/395—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP95905946A 1993-12-30 1994-12-29 Nouvelles utilisations de produits de recombinaison de recepteurs de gal4 Ceased EP0737314A4 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP96111192A EP0743520A3 (fr) 1993-12-30 1994-12-29 Utilisations nouvelles des structures de GAL4-récepteur

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US177740 1988-04-05
US17774093A 1993-12-30 1993-12-30
PCT/US1994/014426 WO1995018380A1 (fr) 1993-12-30 1994-12-29 Nouvelles utilisations de produits de recombinaison de recepteurs de gal4

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP96111192A Division EP0743520A3 (fr) 1993-12-30 1994-12-29 Utilisations nouvelles des structures de GAL4-récepteur

Publications (2)

Publication Number Publication Date
EP0737314A1 EP0737314A1 (fr) 1996-10-16
EP0737314A4 true EP0737314A4 (fr) 1999-11-03

Family

ID=22649809

Family Applications (2)

Application Number Title Priority Date Filing Date
EP95905946A Ceased EP0737314A4 (fr) 1993-12-30 1994-12-29 Nouvelles utilisations de produits de recombinaison de recepteurs de gal4
EP96111192A Withdrawn EP0743520A3 (fr) 1993-12-30 1994-12-29 Utilisations nouvelles des structures de GAL4-récepteur

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP96111192A Withdrawn EP0743520A3 (fr) 1993-12-30 1994-12-29 Utilisations nouvelles des structures de GAL4-récepteur

Country Status (5)

Country Link
EP (2) EP0737314A4 (fr)
JP (2) JPH09504111A (fr)
AU (2) AU1436695A (fr)
CA (2) CA2182908A1 (fr)
WO (1) WO1995018380A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995018380A1 (fr) * 1993-12-30 1995-07-06 The Salk Institute For Biological Studies Nouvelles utilisations de produits de recombinaison de recepteurs de gal4
US5989808A (en) * 1994-06-14 1999-11-23 American Cyanamid Company Identification of compounds affecting specific interaction of peptide binding pairs
US6770446B1 (en) 1994-06-14 2004-08-03 Wyeth Cell systems having specific interaction of peptide binding pairs
WO1997010813A1 (fr) 1995-09-18 1997-03-27 Ligand Pharmaceuticals Incorporated Antagonistes de ppar gamma pour le traitement de l'obesite
US6555339B1 (en) * 1997-04-14 2003-04-29 Arena Pharmaceuticals, Inc. Non-endogenous, constitutively activated human protein-coupled receptors
EP0977892A1 (fr) 1997-04-24 2000-02-09 Institut National De La Sante Et De La Recherche Medicale (Inserm) Procedes et compositions a utiliser dans la modulation de l'expression de genes de metalloproteinases matricielles
KR20010014218A (ko) 1997-06-27 2001-02-26 오노 야꾸힝 고교 가부시키가이샤 신규의 리포터 유전자 ｄｎａ를 포함하는 플라스미드ｄｎａ 및 그 용도
WO1999005292A1 (fr) * 1997-07-22 1999-02-04 Chugai Seiyaku Kabushiki Kaisha Methode de criblage de genes utilisant les recepteurs nucleaires
JP2003520758A (ja) 1998-06-12 2003-07-08 リガンド・ファーマシューティカルズ・インコーポレイテッド 抗エストロゲン耐性乳癌のｒｘｒモジュレーターを用いた処置
AU3725600A (en) * 1999-03-02 2000-09-21 Maxygen, Inc. Surrogate orphan ligands for orphan receptors
DK1248604T4 (da) 2000-01-21 2012-05-21 Novartis Ag Kombinationer indeholdende dipeptidylpeptidase-IV-inhibitorer og antidiabetiske midler
WO2002097099A1 (fr) * 2001-05-29 2002-12-05 Valentis, Inc. Expression regulee de somatostatine
US6696473B2 (en) 2001-12-21 2004-02-24 X-Ceptor Therapeutics, Inc. Heterocyclic modulators of nuclear receptors
EP1388352A1 (fr) 2002-08-08 2004-02-11 Laboratoires Fournier S.A. Utilisation d'un agoniste de PPAR-alpha pour traiter l'obesité associée au traitement avec un agonist de PPAR-gamma dans des patients
EP1544307A1 (fr) * 2003-12-18 2005-06-22 AXXAM S.r.l. Recepteur chimerique LAC9 et ses utilisations
BRPI0612287A8 (pt) 2005-06-27 2019-01-22 Exelixis Inc composição para uso farmacêutico no tratamento de doenças através da medicina nuclear e métodos de uso e para modulação de atividade de receptor nuclear
MY159522A (en) 2005-09-14 2017-01-13 Takeda Pharmaceuticals Co Administration of dipeptidyl peptidase inhibitors
WO2011041293A1 (fr) 2009-09-30 2011-04-07 Takeda Pharmaceutical Company Limited Dérivés pyrazolo [1, 5—a] pyrimidines comme inhibiteurs de kinase 1 régulatrice de signal d'apoptose
RS53176B (en) 2010-02-03 2014-06-30 Takeda Pharmaceutical Company Limited KINASE INHIBITORS 1 REGULATING SIGNALS IN APOPTOSIS
WO2013037482A1 (fr) 2011-09-15 2013-03-21 Phenex Pharmaceuticals Ag Agonistes du récepteur du farnésoïde x pour le traitement et la prévention du cancer
US9074186B2 (en) 2012-08-15 2015-07-07 Boston Medical Center Corporation Production of red blood cells and platelets from stem cells

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992016546A1 (fr) * 1991-03-19 1992-10-01 The Salk Institute For Biological Studies Compositions a element de reaction et dosages les utilisant
WO1993006215A1 (fr) * 1991-09-17 1993-04-01 The Salk Institute For Biological Studies Recepteurs de la superfamille des recepteurs d'hormones thyroidiennes/steroides
WO1993023431A1 (fr) * 1992-05-14 1993-11-25 Baylor College Of Medicine Recepteurs d'hormones steroides mutees, procede d'utilisation et commutateur moleculaire pour therapie genique

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995018380A1 (fr) * 1993-12-30 1995-07-06 The Salk Institute For Biological Studies Nouvelles utilisations de produits de recombinaison de recepteurs de gal4

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992016546A1 (fr) * 1991-03-19 1992-10-01 The Salk Institute For Biological Studies Compositions a element de reaction et dosages les utilisant
WO1993006215A1 (fr) * 1991-09-17 1993-04-01 The Salk Institute For Biological Studies Recepteurs de la superfamille des recepteurs d'hormones thyroidiennes/steroides
WO1993023431A1 (fr) * 1992-05-14 1993-11-25 Baylor College Of Medicine Recepteurs d'hormones steroides mutees, procede d'utilisation et commutateur moleculaire pour therapie genique

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9518380A1 *

Also Published As

Publication number Publication date
EP0743520A2 (fr) 1996-11-20
AU5837496A (en) 1996-10-03
CA2182908A1 (fr) 1995-07-01
AU1436695A (en) 1995-07-17
EP0737314A1 (fr) 1996-10-16
AU700646B2 (en) 1999-01-14
JPH09504111A (ja) 1997-04-22
EP0743520A3 (fr) 1999-11-10
WO1995018380A1 (fr) 1995-07-06
CA2180271A1 (fr) 1995-07-06
JPH09275988A (ja) 1997-10-28

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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