EP0727993A4 - - Google Patents

Info

Publication number
EP0727993A4
EP0727993A4 EP93904656A EP93904656A EP0727993A4 EP 0727993 A4 EP0727993 A4 EP 0727993A4 EP 93904656 A EP93904656 A EP 93904656A EP 93904656 A EP93904656 A EP 93904656A EP 0727993 A4 EP0727993 A4 EP 0727993A4
Authority
EP
European Patent Office
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93904656A
Other versions
EP0727993A1 (fr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of EP0727993A1 publication Critical patent/EP0727993A1/fr
Publication of EP0727993A4 publication Critical patent/EP0727993A4/xx
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP93904656A 1992-01-28 1993-01-27 Procede (non descriptif) de retardement du sida chez des sujets contamines par le vih par administration de composes d'azaspirane substitue Withdrawn EP0727993A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB929201804A GB9201804D0 (en) 1992-01-28 1992-01-28 Methods
GB9201804 1992-01-28
PCT/US1993/000712 WO1993015735A1 (fr) 1992-01-28 1993-01-27 Procede (non descriptif) de retardement du sida chez des sujets contamines par le vih par administration de composes d'azaspirane substitue

Publications (2)

Publication Number Publication Date
EP0727993A1 EP0727993A1 (fr) 1996-08-28
EP0727993A4 true EP0727993A4 (fr) 1996-10-02

Family

ID=10709399

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93904656A Withdrawn EP0727993A1 (fr) 1992-01-28 1993-01-27 Procede (non descriptif) de retardement du sida chez des sujets contamines par le vih par administration de composes d'azaspirane substitue

Country Status (5)

Country Link
EP (1) EP0727993A1 (fr)
JP (1) JPH07504405A (fr)
AU (1) AU3594293A (fr)
GB (1) GB9201804D0 (fr)
WO (1) WO1993015735A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT100566B (pt) * 1991-06-07 1999-06-30 Smithkline Beecham Corp Azaspiranos imunomoduladores, composicoes farmaceuticas que os contem, sua preparacao e seu uso
GB9315340D0 (en) * 1993-07-23 1993-09-08 Smithkline Beecham Corp Methods
GB9315306D0 (en) * 1993-07-23 1993-09-08 Smithkline Beecham Corp Methods
GB9315351D0 (en) * 1993-07-23 1993-09-08 Smithkline Beecham Corp Methods

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0310321A2 (fr) * 1987-09-28 1989-04-05 Smithkline Beecham Corporation Azaspiranes à activité immunomodulatrice
WO1992014462A1 (fr) * 1991-02-19 1992-09-03 Smithkline Beecham Corporation Inhibiteurs de cytokines
WO1992022294A1 (fr) * 1991-06-07 1992-12-23 Smithkline Beecham Corporation Azaspiranes immunomodulateurs

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0310321A2 (fr) * 1987-09-28 1989-04-05 Smithkline Beecham Corporation Azaspiranes à activité immunomodulatrice
WO1992014462A1 (fr) * 1991-02-19 1992-09-03 Smithkline Beecham Corporation Inhibiteurs de cytokines
WO1992022294A1 (fr) * 1991-06-07 1992-12-23 Smithkline Beecham Corporation Azaspiranes immunomodulateurs

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
A.M. BADGER ET AL.: "ANTIARTHRITIC AND SUPPRESSOR CELL INDUCING ACTIVITY OF AZASPIRANES: STRUCTURE-FUNCTION RELATIONSHIPS OF A NOVEL CLASS OF IMMUNOMODULATORY AGENTS", JOURNAL OF MEDICINAL CHEMISTRY, vol. 33, no. 11, 1990, pages 2963 - 2970, XP000605424, DOI: doi:10.1021/jm00173a010 *
J.M. ANDRIEU ET AL.: "EFFECTS OF CYCLOSPORIN ON T-CELL SUBSETS IN HUMAN IMMUNODEFICIENCY VIRUS DISEASE", CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY, vol. 46, 1988, pages 181 - 198, XP026197546, DOI: doi:10.1016/0090-1229(88)90071-2 *
S. GOODMAN: "THERAPEUTIC EFFECTS OF ORGANIC GERMANIUM", MEDICAL HYPOTHESES, vol. 26, no. 3, 1988, pages 207 - 215, XP023027493, DOI: doi:10.1016/0306-9877(88)90101-6 *
See also references of WO9315735A1 *

Also Published As

Publication number Publication date
JPH07504405A (ja) 1995-05-18
GB9201804D0 (en) 1992-03-11
EP0727993A1 (fr) 1996-08-28
WO1993015735A1 (fr) 1993-08-19
AU3594293A (en) 1993-09-03

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 19940729

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