EP0727486A3 - Gene that suppresses tumors - Google Patents

Gene that suppresses tumors Download PDF

Info

Publication number
EP0727486A3
EP0727486A3 EP95101980A EP95101980A EP0727486A3 EP 0727486 A3 EP0727486 A3 EP 0727486A3 EP 95101980 A EP95101980 A EP 95101980A EP 95101980 A EP95101980 A EP 95101980A EP 0727486 A3 EP0727486 A3 EP 0727486A3
Authority
EP
European Patent Office
Prior art keywords
suppressor gene
tumour suppressor
tumour
gene
suppressor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95101980A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP0727486A2 (en
Inventor
Yusuke Nakamura
Takashi Imai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Cancer Institute
Original Assignee
Eisai Co Ltd
Cancer Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP6324795A priority Critical patent/JPH07289297A/ja
Priority to US08/384,850 priority patent/US5559023A/en
Application filed by Eisai Co Ltd, Cancer Institute filed Critical Eisai Co Ltd
Priority to EP95101980A priority patent/EP0727486A3/en
Priority to US08/444,405 priority patent/US5556945A/en
Publication of EP0727486A2 publication Critical patent/EP0727486A2/en
Publication of EP0727486A3 publication Critical patent/EP0727486A3/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP95101980A 1994-02-10 1995-02-14 Gene that suppresses tumors Withdrawn EP0727486A3 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP6324795A JPH07289297A (ja) 1994-02-10 1994-12-27 癌抑制遺伝子
US08/384,850 US5559023A (en) 1994-02-10 1995-02-07 Tumor suppressor gene
EP95101980A EP0727486A3 (en) 1994-02-10 1995-02-14 Gene that suppresses tumors
US08/444,405 US5556945A (en) 1994-02-10 1995-05-19 Tumor suppressor gene

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP3764994 1994-02-10
JP6324795A JPH07289297A (ja) 1994-02-10 1994-12-27 癌抑制遺伝子
EP95101980A EP0727486A3 (en) 1994-02-10 1995-02-14 Gene that suppresses tumors

Publications (2)

Publication Number Publication Date
EP0727486A2 EP0727486A2 (en) 1996-08-21
EP0727486A3 true EP0727486A3 (en) 1996-12-04

Family

ID=27236491

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95101980A Withdrawn EP0727486A3 (en) 1994-02-10 1995-02-14 Gene that suppresses tumors

Country Status (2)

Country Link
EP (1) EP0727486A3 (ja)
JP (1) JPH07289297A (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5976790A (en) 1992-03-04 1999-11-02 The Regents Of The University Of California Comparative Genomic Hybridization (CGH)
US7049424B2 (en) 1996-07-15 2006-05-23 The Regents Of The University Of California Genes from the 20Q13 amplicon and their uses
US7455964B1 (en) 1996-07-15 2008-11-25 The Hospital For Sick Children Genes from the 20q13 amplicon and their uses
US20030060434A1 (en) 1997-02-18 2003-03-27 Loretta Nielsen Combined tumor suppressor gene therapy and chemotherapy in the treatment of neoplasms
US5972649A (en) * 1997-05-29 1999-10-26 Incyte Pharmaceuticals, Inc. Polynucleotide sequence encoding human multiple endocrine neoplasia type 1 protein
WO2003002765A2 (en) 2001-06-27 2003-01-09 Cancer Research Technology Limited Methods for the diagnosis of cancer based on the obcam and ntm genes

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
A. TANIGAMI ET AL.: "A 14-Mb physical map of the region at chromosome 11q13 harboring the MEN1 locus and the tumor amplicon region", GENOMICS, vol. 13, 1992, pages 16 - 20, XP002014711 *
A.J. BUCKLER ET AL.: "Exon amplification; a strategy to isolate mammalian genes based on RNA splicing", PROC. NATL. ACAD. SCI. USA, vol. 88, 1991, pages 4005 - 4009, XP002014710 *
C. BYSTRÖM ET AL.: "Localization of the MEN1 gene to a small region within chromosome 11q13 by deletion mapping in tumors", PROC. NATL. ACAD. SCI. USA, vol. 87, 1990, pages 1968 - 1972, XP002014712 *
M. FUJIMORI ET AL.: "Fine-scale mapping of the gene responsible for multiple endocrine neoplasia type 1 (MEN1)", AM. J. HUM. GENET., vol. 50, 1992, pages 399 - 403, XP002014713 *
T. TODA ET AL.: "Isolation and characterization of a novel gene encoding nuclear protein at a locus (D11S636) tightly linked to multiple endocrine neoplasia type 1 (MEN1)", HUM. MOL. GENET., vol. 3, 1994, pages 465 - 470, XP002014714 *

Also Published As

Publication number Publication date
JPH07289297A (ja) 1995-11-07
EP0727486A2 (en) 1996-08-21

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