EP0724593A4 - Matrices en boucle a axe superenroule - Google Patents

Matrices en boucle a axe superenroule

Info

Publication number
EP0724593A4
EP0724593A4 EP94920179A EP94920179A EP0724593A4 EP 0724593 A4 EP0724593 A4 EP 0724593A4 EP 94920179 A EP94920179 A EP 94920179A EP 94920179 A EP94920179 A EP 94920179A EP 0724593 A4 EP0724593 A4 EP 0724593A4
Authority
EP
European Patent Office
Prior art keywords
coiled
stem loop
loop templates
coil stem
coil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94920179A
Other languages
German (de)
English (en)
Other versions
EP0724593A1 (fr
Inventor
Irwin Morris Chaiken
David Gerard Myszka
Thomas James Graddis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP0724593A1 publication Critical patent/EP0724593A1/fr
Publication of EP0724593A4 publication Critical patent/EP0724593A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5406—IL-4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5412—IL-6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/22011—Polyomaviridae, e.g. polyoma, SV40, JC
    • C12N2710/22022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
EP94920179A 1993-06-11 1994-06-10 Matrices en boucle a axe superenroule Withdrawn EP0724593A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US76088 1987-07-21
US7608893A 1993-06-11 1993-06-11
PCT/US1994/006655 WO1994029332A1 (fr) 1993-06-11 1994-06-10 Matrices en boucle a axe superenroule

Publications (2)

Publication Number Publication Date
EP0724593A1 EP0724593A1 (fr) 1996-08-07
EP0724593A4 true EP0724593A4 (fr) 1997-11-26

Family

ID=22129863

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94920179A Withdrawn EP0724593A4 (fr) 1993-06-11 1994-06-10 Matrices en boucle a axe superenroule

Country Status (3)

Country Link
EP (1) EP0724593A4 (fr)
JP (1) JPH08511542A (fr)
WO (1) WO1994029332A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837816A (en) * 1995-05-10 1998-11-17 Chiron Corporation Interleukin-2 receptor subunit ectodomain fusion protein comprising a leucine zipper domain
US6271198B1 (en) 1996-11-06 2001-08-07 Genentech, Inc. Constrained helical peptides and methods of making same
WO1999025732A2 (fr) * 1997-11-13 1999-05-27 Europäisches Laboratorium für Molekularbiologie (EMBL) Conception, par derivation de dimeres bispirales, d'antagonistes des recepteurs specifiques de cytokines en faisceau de quatre helices
US6709814B1 (en) 1998-04-02 2004-03-23 Rigel Pharmaceuticals, Inc. Peptides causing formation of compact structures
NZ507063A (en) * 1998-04-02 2003-11-28 Rigel Pharmaceuticals Inc Self-dimerising peptides causing the formation of compact structures
GB0019638D0 (en) * 2000-08-09 2000-09-27 European Molecular Biology Lab Embl Peptide mimetics
EP1877054A2 (fr) * 2005-03-30 2008-01-16 Sirtris Pharmaceuticals, Inc. Nicotinamide riboside et analogues
JP6934860B2 (ja) * 2015-09-01 2021-09-15 オンコクール・エムエル・ゲーエムベーハー コイルドコイルコネクタ
DK3423578T3 (da) 2016-03-04 2020-07-20 Morphosys Ag Polypeptidbibliotek
WO2019086694A1 (fr) 2017-11-06 2019-05-09 Geert Mudde Vaccin et antigène il31

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993003160A1 (fr) * 1991-08-09 1993-02-18 E.I. Du Pont De Nemours And Company Proteines de reserve synthetiques a structure definie contenant des taux programmables d'acides amines essentiels en vue de l'amelioration de la valeur nutritionnelle de plantes

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993003160A1 (fr) * 1991-08-09 1993-02-18 E.I. Du Pont De Nemours And Company Proteines de reserve synthetiques a structure definie contenant des taux programmables d'acides amines essentiels en vue de l'amelioration de la valeur nutritionnelle de plantes

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
B.Y. ZHU ET AL: "Design, synthesis and structural charcterisation of model heterodimeric coiled-coil proteins", INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH, vol. 40, 1992, COPENHAGEN DK, pages 171 - 179, XP002041098 *
BAXEVANIS A D ET AL: "INTERACTIONS OF COILED COILS IN TRANSCRIPTION FACTORS: WHERE IS THE SPECIFICITY?", CURRENT OPINION IN GENETICS & DEVELOPMENT, vol. 3, 1993, pages 278 - 285, XP002022679 *
P.T.P. KAUMAYA ET AL.: "Predetermined supersecondary motifs in the dovo design of protein antigenic determinants", PEPTIDES: CHEMISTRY, STRUCTURE AND BIOLOGY - PROCEEDINGS OF THE AMERICAN PEPTIDE SYMPOSIUM, vol. 11, 1990, ESCOM - LEIDEN, NL, pages 709 - 713, XP002041096 *
See also references of WO9429332A1 *
T.J. GIBSON ET AL: "Proposed structure for the DNA-binding domain of the Helix-Loop-Helix family of eukaryotic gene regulatory proteins", PROTEIN ENGINEERING., vol. 6, no. 1, February 1993 (1993-02-01), ENGLAND GB, pages 41 - 50, XP002041097 *

Also Published As

Publication number Publication date
EP0724593A1 (fr) 1996-08-07
WO1994029332A1 (fr) 1994-12-22
JPH08511542A (ja) 1996-12-03

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19960108

AK Designated contracting states

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Designated state(s): BE CH DE FR GB IT LI NL

A4 Supplementary search report drawn up and despatched

Effective date: 19971009

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STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 20000101