EP0714399A4 - Hsv-2 ul26 gene, capsid proteins, immunoassays and protease inhibitors - Google Patents

Hsv-2 ul26 gene, capsid proteins, immunoassays and protease inhibitors

Info

Publication number
EP0714399A4
EP0714399A4 EP94925924A EP94925924A EP0714399A4 EP 0714399 A4 EP0714399 A4 EP 0714399A4 EP 94925924 A EP94925924 A EP 94925924A EP 94925924 A EP94925924 A EP 94925924A EP 0714399 A4 EP0714399 A4 EP 0714399A4
Authority
EP
European Patent Office
Prior art keywords
hsv
immunoassays
gene
protease inhibitors
capsid proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94925924A
Other languages
German (de)
French (fr)
Other versions
EP0714399A1 (en
Inventor
Anthony G Dilella
Christine Marie Debouck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP0714399A1 publication Critical patent/EP0714399A1/en
Publication of EP0714399A4 publication Critical patent/EP0714399A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56994—Herpetoviridae, e.g. cytomegalovirus, Epstein-Barr virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01—DNA viruses
    • G01N2333/03—Herpetoviridae, e.g. pseudorabies virus
    • G01N2333/035—Herpes simplex virus I or II
EP94925924A 1993-08-20 1994-08-19 Hsv-2 ul26 gene, capsid proteins, immunoassays and protease inhibitors Withdrawn EP0714399A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US110522 1987-10-20
US11052293A 1993-08-20 1993-08-20
US26453794A 1994-06-23 1994-06-23
US264537 1994-06-23
PCT/US1994/009303 WO1995006055A1 (en) 1993-08-20 1994-08-19 Hsv-2 ul26 gene, capsid proteins, immunoassays and protease inhibitors

Publications (2)

Publication Number Publication Date
EP0714399A1 EP0714399A1 (en) 1996-06-05
EP0714399A4 true EP0714399A4 (en) 1999-01-27

Family

ID=26808107

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94925924A Withdrawn EP0714399A4 (en) 1993-08-20 1994-08-19 Hsv-2 ul26 gene, capsid proteins, immunoassays and protease inhibitors

Country Status (7)

Country Link
EP (1) EP0714399A4 (en)
JP (1) JPH09503385A (en)
CN (1) CN1133594A (en)
AU (1) AU7568294A (en)
CA (1) CA2169748A1 (en)
MX (1) MXPA94006367A (en)
WO (1) WO1995006055A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6083711A (en) * 1996-05-15 2000-07-04 Smithkline Beecham Corporation Proteases compositions capable of binding to said site, and methods of use thereof
WO1998000567A1 (en) * 1996-07-01 1998-01-08 Université de Montréal Identification of a transforming fragment of herpes simplex type 2 and detection thereof in clinical specimens
JP2001508649A (en) * 1996-11-04 2001-07-03 スミスクライン・ビーチャム・コーポレイション Novel coding sequence from herpes simplex virus type 2
US6143513A (en) * 1999-06-23 2000-11-07 Biacore Ab Method and kit for detecting betalactam-containing compounds
ATE494907T1 (en) 2002-07-18 2011-01-15 Univ Washington PHARMACEUTICAL COMPOSITIONS CONTAINING IMMUNOLOGICALLY ACTIVE HERPES SIMPLEX VIRUS PROTEIN FRAGMENTS
US8460674B2 (en) 2009-02-07 2013-06-11 University Of Washington HSV-1 epitopes and methods for using same
US9044447B2 (en) 2009-04-03 2015-06-02 University Of Washington Antigenic peptide of HSV-2 and methods for using same
NZ597182A (en) 2009-05-22 2014-07-25 Genocea Biosciences Inc Vaccines against herpes simplex virus type 2: compositions and methods for eliciting an immune response
CN101974613A (en) * 2010-10-15 2011-02-16 成都医学院 Kit and method for screening anti-herpes simplex virus-I (anti-HSV-I) medicament
WO2012074881A2 (en) 2010-11-24 2012-06-07 Genocea Biosciences, Inc. Vaccines against herpes simplex virus type 2: compositions and methods for eliciting an immune response
EP2782597B1 (en) 2011-11-23 2022-04-13 Genocea Biosciences, Inc. Nucleic acid vaccines against herpes simplex virus type 2: compositions and methods for eliciting an immune response
CN107305212B (en) * 2016-04-25 2019-08-30 赵芳 A kind of immunological detection method and kit of organophosphate and carbamate pesticide
CN107305213A (en) * 2016-04-25 2017-10-31 赵芳 A kind of method and kit for detecting organophosphate and carbamate pesticide
WO2018064232A1 (en) 2016-09-28 2018-04-05 Genocea Biosciences, Inc. Methods and compositions for treating herpes

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4430437A (en) * 1980-08-27 1984-02-07 The United States Of America As Represented By The Department Of Health And Human Services Test methods employing monoclonal antibodies against Herpes simplex virus types 1 and 2 nucleocapsids proteins
EP0514830A2 (en) * 1991-05-24 1992-11-25 Arch Development Corporation Methods and compositions of a preparation and use of a herpes protease
WO1993001291A1 (en) * 1991-07-05 1993-01-21 The Johns Hopkins University Herpes virus proteinase and method of assaying
EP0526652A1 (en) * 1991-02-25 1993-02-10 Iatron Laboratories, Inc. Method of type-specific detection of herpes simplex virus
WO1994029456A2 (en) * 1993-06-08 1994-12-22 Abbott Laboratories Herpes simplex virus type-2 protease

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4709011A (en) * 1982-02-18 1987-11-24 University Patents, Inc. Materials and methods for herpes simplex virus vaccination
US4891315A (en) * 1982-10-25 1990-01-02 American Cyanamid Company Production of herpes simplex viral porteins
US4618578A (en) * 1984-07-17 1986-10-21 Chiron Corporation Expression of glycoprotein D of herpes simplex virus
US5324664A (en) * 1988-08-08 1994-06-28 The Upjohn Company Herpes virus thymidien kinase-encoding DNA
US5122449A (en) * 1988-10-07 1992-06-16 Eastman Kodak Company Use of a protease in the extraction of chlamydial, gonococcal and herpes antigens

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4430437A (en) * 1980-08-27 1984-02-07 The United States Of America As Represented By The Department Of Health And Human Services Test methods employing monoclonal antibodies against Herpes simplex virus types 1 and 2 nucleocapsids proteins
EP0526652A1 (en) * 1991-02-25 1993-02-10 Iatron Laboratories, Inc. Method of type-specific detection of herpes simplex virus
EP0514830A2 (en) * 1991-05-24 1992-11-25 Arch Development Corporation Methods and compositions of a preparation and use of a herpes protease
WO1993001291A1 (en) * 1991-07-05 1993-01-21 The Johns Hopkins University Herpes virus proteinase and method of assaying
WO1994029456A2 (en) * 1993-06-08 1994-12-22 Abbott Laboratories Herpes simplex virus type-2 protease

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9506055A1 *

Also Published As

Publication number Publication date
AU7568294A (en) 1995-03-21
MXPA94006367A (en) 2004-09-09
EP0714399A1 (en) 1996-06-05
CA2169748A1 (en) 1995-03-02
JPH09503385A (en) 1997-04-08
WO1995006055A1 (en) 1995-03-02
CN1133594A (en) 1996-10-16

Similar Documents

Publication Publication Date Title
MXPA99002203A (en) Novel acetamide derivatives and protease inhibitors.
AU4236796A (en) Cysteine protease and serine protease inhibitors
EP0650844A3 (en) Shuttle-type-printers and methods for operating same.
DE69727586D1 (en) Cysteine protease inhibitoren
HK1014950A1 (en) Hiv protease inhibitors.
ZA957263B (en) Improved proteolytic enzyme cleaner.
HUP0000427A3 (en) Benzamidoaldehydes and their use as cysteine protease inhibitors
ZA971810B (en) Alkylphenylbisacylphosphine oxides and photoinitiator mixtures.
EP0611168A3 (en) Hop extract and use thereof.
IL97428A0 (en) Chymotrypsin-like proteases and their inhibitors
ZA977694B (en) Heterocyclic metalloprotease inhibitors.
AU6121394A (en) Methods and reagents for inhibiting furin endoprotease
ZA9710646B (en) Aminoguanidines and alkoxyguanidines as protease inhibitors
ZA978098B (en) Designer proteases
EP0714399A4 (en) Hsv-2 ul26 gene, capsid proteins, immunoassays and protease inhibitors
GB9405242D0 (en) Developers for ps plates and replinishers therefor
NZ331486A (en) Serine protease inhibitors
AU2861695A (en) Mn gene and protein
AU5340399A (en) Proteases and associated proteins
HK1021541A1 (en) Serine protease inhibitors
AU7139598A (en) Protease inhibitors
DE69713352D1 (en) Substituierte [2-(1-piperazinyl)ethoxy]methyl-derivate
EP0777746A4 (en) Assay for the detection of proteases
EP0758891A4 (en) HALOMETHYL AMIDES AS IL-1-g(b) PROTEASE INHIBITORS
AU7518694A (en) Retroviral protease inhibitors and combinations thereof

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19960306

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

AX Request for extension of the european patent

Free format text: SI PAYMENT 960306

RAX Requested extension states of the european patent have changed

Free format text: SI PAYMENT 960306

A4 Supplementary search report drawn up and despatched

Effective date: 19981215

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

RHK1 Main classification (correction)

Ipc: C12N 15/57

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19990302