EP0697871A4 - Treatment process with biologically active tropane derivatives - Google Patents

Treatment process with biologically active tropane derivatives

Info

Publication number
EP0697871A4
EP0697871A4 EP94915779A EP94915779A EP0697871A4 EP 0697871 A4 EP0697871 A4 EP 0697871A4 EP 94915779 A EP94915779 A EP 94915779A EP 94915779 A EP94915779 A EP 94915779A EP 0697871 A4 EP0697871 A4 EP 0697871A4
Authority
EP
European Patent Office
Prior art keywords
biologically active
treatment process
tropane derivatives
active tropane
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94915779A
Other languages
German (de)
French (fr)
Other versions
EP0697871A1 (en
Inventor
Huw M L Davies
Stevens R Childers
Barbara Bennett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wake Forest University
Original Assignee
Wake Forest University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/063,431 external-priority patent/US6008227A/en
Application filed by Wake Forest University filed Critical Wake Forest University
Publication of EP0697871A1 publication Critical patent/EP0697871A1/en
Publication of EP0697871A4 publication Critical patent/EP0697871A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP94915779A 1993-05-18 1994-04-04 Treatment process with biologically active tropane derivatives Withdrawn EP0697871A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/063,431 US6008227A (en) 1992-03-13 1993-05-18 Process for blocking 5-HT and dopamine uptake with biologically active tropane derivatives
US63431 1993-05-18
PCT/US1994/003661 WO1994026274A1 (en) 1993-05-18 1994-04-04 Treatment process with biologically active tropane derivatives

Publications (2)

Publication Number Publication Date
EP0697871A1 EP0697871A1 (en) 1996-02-28
EP0697871A4 true EP0697871A4 (en) 1998-04-22

Family

ID=22049138

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94915779A Withdrawn EP0697871A4 (en) 1993-05-18 1994-04-04 Treatment process with biologically active tropane derivatives

Country Status (5)

Country Link
EP (1) EP0697871A4 (en)
JP (1) JP2906085B2 (en)
AU (1) AU673265B2 (en)
CA (1) CA2163095A1 (en)
WO (1) WO1994026274A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE362931T1 (en) * 1995-10-13 2007-06-15 Neurosearch As 8-AZABICYCLO(3.2.1)OCT-2EN DERIVATIVES, THEIR PRODUCTION AND APPLICATION
US7105678B2 (en) 1995-11-03 2006-09-12 Organix, Inc. Boat tropanes
CA2285516C (en) * 1999-05-12 2010-12-07 President And Fellows Of Harvard College Dopamine transporter imaging agents
GB9920074D0 (en) * 1999-08-24 1999-10-27 Babraham Inst Animal model and uses thereof
DK1513529T3 (en) * 2002-05-30 2012-03-26 Neurosearch As THREE-TERM MONOAMIN RECOVERY INHIBITORS FOR TREATMENT OF CHRONIC PAIN
WO2007028770A1 (en) * 2005-09-05 2007-03-15 Neurosearch A/S Monoamine neurotransmitter re-uptake inhibitors for neuroprotection in patients suffering from an advanced stage of a mental disease

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993018033A1 (en) * 1992-03-13 1993-09-16 Wake Forest University Biologically active tropane derivatives
US5288872A (en) * 1992-03-13 1994-02-22 Wake Forest University Compounds for treatment of neurodegenerative diseases
EP0604354A2 (en) * 1992-12-23 1994-06-29 Neurosearch A/S Antidepressant and antiparkinsonian compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3813404A (en) * 1972-11-15 1974-05-28 Sterling Drug Inc Tropane-2-carboxylates and derivatives

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993018033A1 (en) * 1992-03-13 1993-09-16 Wake Forest University Biologically active tropane derivatives
US5288872A (en) * 1992-03-13 1994-02-22 Wake Forest University Compounds for treatment of neurodegenerative diseases
EP0604354A2 (en) * 1992-12-23 1994-06-29 Neurosearch A/S Antidepressant and antiparkinsonian compounds

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DAVIES H.M.L. ET AL: "Synthesis of 2beta-Acyl-3beta-aryl-8-azabicyclo[3.2.1.]octanes and Their Binding Affinities at Dopamine and Serotonin Transport Sites in Rat Striatum and Frontal Cortex", J. MED. CHEM., vol. 37, no. 9, 1 April 1994 (1994-04-01), pages 1262 - 1268, XP002056000 *
See also references of WO9426274A1 *

Also Published As

Publication number Publication date
JP2906085B2 (en) 1999-06-14
WO1994026274A1 (en) 1994-11-24
AU673265B2 (en) 1996-10-31
CA2163095A1 (en) 1994-11-24
EP0697871A1 (en) 1996-02-28
JPH08510238A (en) 1996-10-29
AU6767194A (en) 1994-12-12

Similar Documents

Publication Publication Date Title
HUT64764A (en) Carbapenem-derivatives with antibiotic effect and medical preparatives containing them and process for the production thereof
HU910354D0 (en) Process for producing 4-isoxazole-carboxamide derivatives and paharmaceutical preparatives containing such active agents
LTIP599A (en) Novel, biologically active eburnamenine derivatives and a process for preparing the same
EP0697871A4 (en) Treatment process with biologically active tropane derivatives
AU4947493A (en) Hollow textile body and process for making it
IL107768A0 (en) Treatment of agricultural produce
GB9308802D0 (en) Treatment
AU5538794A (en) Biologically active compounds and process therefor
ZA945190B (en) Carboxymethylidenecycloheptimidazole derivatives method or manufacturing the same and therapeutic agents containing these compounds
AU4096689A (en) The use of lactam derivatives in the treatment of addiction
GB2241958B (en) Treatment process
GB2243602B (en) Treatment process
GB9415113D0 (en) Plant treatment
ZA948930B (en) Treatment of compost
IE893379L (en) Composition and treatment with biologically active peptides¹and certain anions
GB9316508D0 (en) Biologically active molecules
GB9310608D0 (en) Biologically active dermatological treatment
GB9218907D0 (en) Biologically active molecules
IE901329L (en) Composition and treatment with biologically active peptides¹and antibiotic
GB8806451D0 (en) Biologically active molecules
GB2279548B (en) Crop treatment
GB9218772D0 (en) Biologically active dermatological treatment
HU911248D0 (en) Phytoactive preparatives and process for producing them as well as their active agents
ZA948336B (en) Treatment
GB9310836D0 (en) Treatment

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19951114

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

A4 Supplementary search report drawn up and despatched

Effective date: 19980309

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

17Q First examination report despatched

Effective date: 19980519

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20000706