EP0686265A4 - Verfahren zum induzieren von immunität gegen die lyme-krankheit und ein kolorimetrischer test auf borreliazide aktivität von antisera - Google Patents

Verfahren zum induzieren von immunität gegen die lyme-krankheit und ein kolorimetrischer test auf borreliazide aktivität von antisera

Info

Publication number
EP0686265A4
EP0686265A4 EP94910185A EP94910185A EP0686265A4 EP 0686265 A4 EP0686265 A4 EP 0686265A4 EP 94910185 A EP94910185 A EP 94910185A EP 94910185 A EP94910185 A EP 94910185A EP 0686265 A4 EP0686265 A4 EP 0686265A4
Authority
EP
European Patent Office
Prior art keywords
antisera
methods
lyme disease
colorimetric assay
inducing immunity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94910185A
Other languages
English (en)
French (fr)
Other versions
EP0686265A1 (de
Inventor
Richard T Coughlin
Jianneng Ma
Dante J Marciani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cambridge Biotech Corp
Original Assignee
Cambridge Biotech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cambridge Biotech Corp filed Critical Cambridge Biotech Corp
Publication of EP0686265A1 publication Critical patent/EP0686265A1/de
Publication of EP0686265A4 publication Critical patent/EP0686265A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0225—Spirochetes, e.g. Treponema, Leptospira, Borrelia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1207—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP94910185A 1993-02-26 1994-02-28 Verfahren zum induzieren von immunität gegen die lyme-krankheit und ein kolorimetrischer test auf borreliazide aktivität von antisera Withdrawn EP0686265A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2537993A 1993-02-26 1993-02-26
US25379 1993-02-26
PCT/US1994/002095 WO1994019697A1 (en) 1993-02-26 1994-02-28 Methods of inducing immunity to lyme disease and a colorimetric assay for borreliacidal activity of antisera

Publications (2)

Publication Number Publication Date
EP0686265A1 EP0686265A1 (de) 1995-12-13
EP0686265A4 true EP0686265A4 (de) 2001-08-22

Family

ID=21825691

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94910185A Withdrawn EP0686265A4 (de) 1993-02-26 1994-02-28 Verfahren zum induzieren von immunität gegen die lyme-krankheit und ein kolorimetrischer test auf borreliazide aktivität von antisera

Country Status (5)

Country Link
EP (1) EP0686265A4 (de)
AU (1) AU689466B2 (de)
CA (1) CA2157004A1 (de)
NZ (1) NZ262821A (de)
WO (1) WO1994019697A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7008625B2 (en) 1993-11-01 2006-03-07 Research Foundation Of The State University Of New York Recombinant constructs of Borrelia burgdorferi
ES2272296T3 (es) 1999-06-18 2007-05-01 Research Foundation Of State University Of New York Grupos de borrelia burgdorferi que producen la enfermedad de lyme en humanos.
EP1311540B1 (de) 2000-08-18 2007-12-19 Research Foundation Of State University Of New York Veränderte borrelia burgdorferi ospa
BRPI0719360B1 (pt) 2006-11-03 2016-09-06 Intervet Int Bv vacina da doença de lyme canina, e, uso de organismos de uma genoespécie de borrelia
US9316652B2 (en) 2010-09-21 2016-04-19 Stichting Katholieke Universiteit Method for diagnosing Lyme disease using a cellular immunological test
RU2660572C1 (ru) * 2017-04-26 2018-07-06 Федеральное Государственное Бюджетное Образовательное Учреждение Высшего Образования "Красноярский Государственный Медицинский Университет Имени Профессора В.Ф. Войно-Ясенецкого" Министерства Здравоохранения Российской Федерации Способ оценки вероятности исходов эритемной формы иксодового клещевого боррелиоза

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0540457A1 (de) * 1991-10-22 1993-05-05 Symbicom Ab Verbesserungen der Diagnose und der Prophylaxe von Borrelia burgdorferi

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4806350A (en) * 1986-04-18 1989-02-21 Norden Laboratories, Inc. Vaccine formulation
US4721617A (en) * 1986-08-14 1988-01-26 Regents Of The University Of Minnesota Vaccine against lyme disease

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0540457A1 (de) * 1991-10-22 1993-05-05 Symbicom Ab Verbesserungen der Diagnose und der Prophylaxe von Borrelia burgdorferi

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BIOLOGICAL ABSTRACTS, 1 January 1900, Philadelphia, PA, US; abstract no. 1991-381408, HUM W T, ET AL: "CLONING EXPRESSION AND PURIFICATION OF BORRELIA-BURGDORFERI OSPA A CANDIDATE VACCINE FOR LYME DISEASE" XP002170803 *
See also references of WO9419697A1 *
W.T. HUM ET AL.: "CLONING EXPRESSION AND PURIFICATION OF BORRELIA BURGDORFERI OSPA A CANDIDATE VACCINE FOR LYME DISEASE.", ABSTRACTS OF THE GENERAL MEETING OF THE AMERICAN SOCIETY OF MICROBIOLOGY 1991, vol. 91, 5 May 1991 (1991-05-05), Dallas TX USA, pages 124 *

Also Published As

Publication number Publication date
NZ262821A (en) 1997-03-24
AU689466B2 (en) 1998-04-02
CA2157004A1 (en) 1994-09-01
EP0686265A1 (de) 1995-12-13
AU6272894A (en) 1994-09-14
WO1994019697A1 (en) 1994-09-01

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