EP0671950A4 - Immunological purging of tumor cells from bone marrow using microspheres and monoclonal antibodies. - Google Patents

Immunological purging of tumor cells from bone marrow using microspheres and monoclonal antibodies.

Info

Publication number
EP0671950A4
EP0671950A4 EP93923903A EP93923903A EP0671950A4 EP 0671950 A4 EP0671950 A4 EP 0671950A4 EP 93923903 A EP93923903 A EP 93923903A EP 93923903 A EP93923903 A EP 93923903A EP 0671950 A4 EP0671950 A4 EP 0671950A4
Authority
EP
European Patent Office
Prior art keywords
microspheres
purging
immunological
monoclonal antibodies
tumor cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93923903A
Other languages
German (de)
French (fr)
Other versions
EP0671950A1 (en
Inventor
Stuart F Schlossman
Lee M Nadler
Arnold S Freedman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dana Farber Cancer Institute Inc
Original Assignee
Dana Farber Cancer Institute Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dana Farber Cancer Institute Inc filed Critical Dana Farber Cancer Institute Inc
Publication of EP0671950A1 publication Critical patent/EP0671950A1/en
Publication of EP0671950A4 publication Critical patent/EP0671950A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3061—Blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP93923903A 1992-10-19 1993-10-18 Immunological purging of tumor cells from bone marrow using microspheres and monoclonal antibodies. Withdrawn EP0671950A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96310492A 1992-10-19 1992-10-19
US963104 1992-10-19
PCT/US1993/009891 WO1994008621A1 (en) 1992-10-19 1993-10-18 Immunological purging of tumor cells from bone marrow using microspheres and monoclonal antibodies

Publications (2)

Publication Number Publication Date
EP0671950A1 EP0671950A1 (en) 1995-09-20
EP0671950A4 true EP0671950A4 (en) 1996-07-31

Family

ID=25506759

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93923903A Withdrawn EP0671950A4 (en) 1992-10-19 1993-10-18 Immunological purging of tumor cells from bone marrow using microspheres and monoclonal antibodies.

Country Status (5)

Country Link
EP (1) EP0671950A4 (en)
JP (1) JPH08502489A (en)
AU (1) AU681605B2 (en)
CA (1) CA2147010A1 (en)
WO (1) WO1994008621A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100124741A1 (en) * 2008-11-18 2010-05-20 Quest Disgnostics Investments Incorporated METHODS FOR DETECTING IgH/BCL-1 CHROMOSOMAL TRANSLOCATION
EP3527659A1 (en) * 2018-02-14 2019-08-21 Universidad del Pais Vasco Method for obtaining a spermatozoid cell population with improved fitness

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986005188A1 (en) * 1985-03-05 1986-09-12 Dana-Farber Cancer Institute, Inc. Monoclonal antibodies and assay
WO1990010692A1 (en) * 1989-03-15 1990-09-20 University Of Florida Monoclonal antibody for use in detection and treatment of childhood leukemia

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986005188A1 (en) * 1985-03-05 1986-09-12 Dana-Farber Cancer Institute, Inc. Monoclonal antibodies and assay
WO1990010692A1 (en) * 1989-03-15 1990-09-20 University Of Florida Monoclonal antibody for use in detection and treatment of childhood leukemia

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE MEDLINE FILE SEVER STN KARLSRUHE; BERREBI ET AL: "FURTHER CHARACTERIZATION OF PROLYMPHOCYTIC LEUKEMIA CELLS AS A TUMOR OF ACTIVATED B CELLS", XP002003405 *
DE FABRITIIS ET AL: "ELIMINATION OF CLONOGENIC BURKITT'S LYMPHOMA CELLS FROM HUMAN BONE MARROW USING 4-HYDROPEROXYCYCLOPHOSPHAMIDE IN COMBINATION WITH MONOCLONAL ANTIBODIES AND COMPLEMENT", BLOOD, vol. 65, no. 5, May 1985 (1985-05-01), pages 1064 - 1070, XP002003403 *
See also references of WO9408621A1 *
STASHENKO ET AL: "CHARACTERIZATION OF A HUMAN B LYMPHOCYTE-SPECIFIC ANTIGEN", THE JOURNAL OF IMMUNOLOGY, vol. 125, no. 4, October 1980 (1980-10-01), pages 1678 - 1685, XP002003404 *

Also Published As

Publication number Publication date
JPH08502489A (en) 1996-03-19
AU5361694A (en) 1994-05-09
EP0671950A1 (en) 1995-09-20
AU681605B2 (en) 1997-09-04
CA2147010A1 (en) 1994-04-28
WO1994008621A1 (en) 1994-04-28

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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