EP0654043A4 - Procede pour preparer une proteine marquee par un radionucleide de metal. - Google Patents
Procede pour preparer une proteine marquee par un radionucleide de metal.Info
- Publication number
- EP0654043A4 EP0654043A4 EP94915454A EP94915454A EP0654043A4 EP 0654043 A4 EP0654043 A4 EP 0654043A4 EP 94915454 A EP94915454 A EP 94915454A EP 94915454 A EP94915454 A EP 94915454A EP 0654043 A4 EP0654043 A4 EP 0654043A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- radionuclide
- preparing
- metal
- labelled protein
- labelled
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/081—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the protein being an albumin, e.g. human serum albumin [HSA], bovine serum albumin [BSA], ovalbumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP94915454A EP0654043A4 (fr) | 1993-05-03 | 1994-05-02 | Procede pour preparer une proteine marquee par un radionucleide de metal. |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP93201249 | 1993-05-03 | ||
EP93201249 | 1993-05-03 | ||
EP94915454A EP0654043A4 (fr) | 1993-05-03 | 1994-05-02 | Procede pour preparer une proteine marquee par un radionucleide de metal. |
PCT/US1994/005022 WO1994025488A1 (fr) | 1993-05-03 | 1994-05-02 | Procede pour preparer une proteine marquee par un radionucleide de metal |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0654043A1 EP0654043A1 (fr) | 1995-05-24 |
EP0654043A4 true EP0654043A4 (fr) | 1997-07-16 |
Family
ID=8213808
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP94915454A Withdrawn EP0654043A4 (fr) | 1993-05-03 | 1994-05-02 | Procede pour preparer une proteine marquee par un radionucleide de metal. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0654043A4 (fr) |
AU (1) | AU6670894A (fr) |
CA (1) | CA2141739A1 (fr) |
MX (1) | MXPA94003278A (fr) |
WO (1) | WO1994025488A1 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5746996A (en) * | 1994-06-03 | 1998-05-05 | Immunomedics, Inc. | Thiolation of peptides for radionuclide-based radiodetection and radiotherapy |
GB9621137D0 (en) * | 1996-10-10 | 1996-11-27 | Chas A Blatchford And Sons Lim | An above-knee lower limb prosthesis and a shin component for the prosthesis |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2752720A1 (de) * | 1976-12-03 | 1978-06-08 | Squibb & Sons Inc | Substituierte aminosaeuren |
EP0248506A1 (fr) * | 1986-03-05 | 1987-12-09 | Mallinckrodt, Inc. (a Delaware corporation) | Marquage de molécules de support par les ions métalliques |
WO1989007456A1 (fr) * | 1988-02-09 | 1989-08-24 | Mallinckrodt, Inc. | Procede de preparation d'une proteine marquee par un nucleide radio-metallique |
WO1989012625A1 (fr) * | 1988-06-15 | 1989-12-28 | Centocor, Inc. | Agents d'accouplement bifonctionnels et compostions marquees par radionucleide preparees a partir desdits agents |
WO1991007991A1 (fr) * | 1989-11-30 | 1991-06-13 | Mallinckrodt Medical, Inc. | Procede de preparation d'une proteine marquee par un radionuclide de metal |
WO1992007876A1 (fr) * | 1990-10-24 | 1992-05-14 | Henning Berlin Gmbh Chemie- Und Pharmawerk | Conjugue ligand-proteine de transport |
US5162505A (en) * | 1989-09-19 | 1992-11-10 | Centocor | Proteins modified with positively charged carriers and compositions prepared therefrom |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4479930A (en) * | 1982-07-26 | 1984-10-30 | Trustees Of The University Of Massachusetts | Amines coupled wth dicyclic dianhydrides capable of being radiolabeled product |
US4877868A (en) * | 1986-03-12 | 1989-10-31 | Neorx Corporation | Radionuclide antibody coupling |
-
1994
- 1994-05-02 CA CA002141739A patent/CA2141739A1/fr not_active Abandoned
- 1994-05-02 WO PCT/US1994/005022 patent/WO1994025488A1/fr not_active Application Discontinuation
- 1994-05-02 EP EP94915454A patent/EP0654043A4/fr not_active Withdrawn
- 1994-05-02 AU AU66708/94A patent/AU6670894A/en not_active Abandoned
- 1994-05-03 MX MX9403278A patent/MXPA94003278A/es unknown
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2752720A1 (de) * | 1976-12-03 | 1978-06-08 | Squibb & Sons Inc | Substituierte aminosaeuren |
EP0248506A1 (fr) * | 1986-03-05 | 1987-12-09 | Mallinckrodt, Inc. (a Delaware corporation) | Marquage de molécules de support par les ions métalliques |
WO1989007456A1 (fr) * | 1988-02-09 | 1989-08-24 | Mallinckrodt, Inc. | Procede de preparation d'une proteine marquee par un nucleide radio-metallique |
WO1989012625A1 (fr) * | 1988-06-15 | 1989-12-28 | Centocor, Inc. | Agents d'accouplement bifonctionnels et compostions marquees par radionucleide preparees a partir desdits agents |
US5162505A (en) * | 1989-09-19 | 1992-11-10 | Centocor | Proteins modified with positively charged carriers and compositions prepared therefrom |
WO1991007991A1 (fr) * | 1989-11-30 | 1991-06-13 | Mallinckrodt Medical, Inc. | Procede de preparation d'une proteine marquee par un radionuclide de metal |
WO1992007876A1 (fr) * | 1990-10-24 | 1992-05-14 | Henning Berlin Gmbh Chemie- Und Pharmawerk | Conjugue ligand-proteine de transport |
Non-Patent Citations (3)
Title |
---|
CHEMICAL ABSTRACTS, vol. 103, no. 25, 23 December 1985, Columbus, Ohio, US; abstract no. 215767, XP002027314 * |
HAYASHI YOSHIO ET AL.: "APPLICATION OF A NEW HETEROBIFUNCTIONAL CONJUGATING REAGENT, DNPVB AND A NEW SH-INTRODUCING REAGENT, MTPTT.", PEPT. CHEM., vol. 22ND, 1985, pages 19 - 22 * |
See also references of WO9425488A1 * |
Also Published As
Publication number | Publication date |
---|---|
CA2141739A1 (fr) | 1994-11-10 |
EP0654043A1 (fr) | 1995-05-24 |
WO1994025488A1 (fr) | 1994-11-10 |
AU6670894A (en) | 1994-11-21 |
MXPA94003278A (es) | 2005-04-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19950113 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI NL PT SE |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: VERBRUGGEN, ALFONS M. |
|
RHK1 | Main classification (correction) |
Ipc: C07K 15/00 |
|
RHK1 | Main classification (correction) |
Ipc: A61K 49/02 |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19970603 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI NL PT SE |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 19970815 |