AU6670894A - Method for preparing a metal-radionuclide-labelled protein - Google Patents

Method for preparing a metal-radionuclide-labelled protein

Info

Publication number
AU6670894A
AU6670894A AU66708/94A AU6670894A AU6670894A AU 6670894 A AU6670894 A AU 6670894A AU 66708/94 A AU66708/94 A AU 66708/94A AU 6670894 A AU6670894 A AU 6670894A AU 6670894 A AU6670894 A AU 6670894A
Authority
AU
Australia
Prior art keywords
radionuclide
preparing
metal
labelled protein
labelled
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU66708/94A
Inventor
Alfons M. Verbruggen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Inc
Original Assignee
Mallinckrodt Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Medical Inc filed Critical Mallinckrodt Medical Inc
Publication of AU6670894A publication Critical patent/AU6670894A/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/081Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the protein being an albumin, e.g. human serum albumin [HSA], bovine serum albumin [BSA], ovalbumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU66708/94A 1993-05-03 1994-05-02 Method for preparing a metal-radionuclide-labelled protein Abandoned AU6670894A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP93201249 1993-05-03
EP93201249 1993-05-03
PCT/US1994/005022 WO1994025488A1 (en) 1993-05-03 1994-05-02 Method for preparing a metal-radionuclide-labelled protein

Publications (1)

Publication Number Publication Date
AU6670894A true AU6670894A (en) 1994-11-21

Family

ID=8213808

Family Applications (1)

Application Number Title Priority Date Filing Date
AU66708/94A Abandoned AU6670894A (en) 1993-05-03 1994-05-02 Method for preparing a metal-radionuclide-labelled protein

Country Status (5)

Country Link
EP (1) EP0654043A4 (en)
AU (1) AU6670894A (en)
CA (1) CA2141739A1 (en)
MX (1) MXPA94003278A (en)
WO (1) WO1994025488A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5746996A (en) * 1994-06-03 1998-05-05 Immunomedics, Inc. Thiolation of peptides for radionuclide-based radiodetection and radiotherapy
GB9621137D0 (en) * 1996-10-10 1996-11-27 Chas A Blatchford And Sons Lim An above-knee lower limb prosthesis and a shin component for the prosthesis

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4116962A (en) * 1976-12-03 1978-09-26 E. R. Squibb & Sons, Inc. Pyrrolidine and piperidine-2-carboxylic acid derivatives
US4479930A (en) * 1982-07-26 1984-10-30 Trustees Of The University Of Massachusetts Amines coupled wth dicyclic dianhydrides capable of being radiolabeled product
US4732974A (en) * 1986-03-05 1988-03-22 Mallinckrodt, Inc. Metal ion labeling of carrier molecules
US4877868A (en) * 1986-03-12 1989-10-31 Neorx Corporation Radionuclide antibody coupling
DE68923274T2 (en) * 1988-02-09 1995-11-09 Mallinckrodt Inc METHOD FOR PRODUCING A PROTEIN MARKED WITH METAL RADIONUCLIDE.
US5218128A (en) * 1988-06-15 1993-06-08 Centocor, Inc. Bifunctional coupling agents and radionuclide labeled compositions prepared therefrom
US5162505A (en) * 1989-09-19 1992-11-10 Centocor Proteins modified with positively charged carriers and compositions prepared therefrom
CA2069868A1 (en) * 1989-11-30 1991-05-31 Wilhelmus T. Goedemans Method for preparing a metal-radionuclide-labelled protein
DE4033714C3 (en) * 1990-10-24 1995-09-07 Brahms Diagnostica Gmbh New hapten analysis based on the principle of an antigen-antibody reaction

Also Published As

Publication number Publication date
MXPA94003278A (en) 2005-04-01
CA2141739A1 (en) 1994-11-10
EP0654043A4 (en) 1997-07-16
EP0654043A1 (en) 1995-05-24
WO1994025488A1 (en) 1994-11-10

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