EP0644769A4 - Biologisch aktive peptide mit n-terminalen substitutionen. - Google Patents
Biologisch aktive peptide mit n-terminalen substitutionen.Info
- Publication number
- EP0644769A4 EP0644769A4 EP93915173A EP93915173A EP0644769A4 EP 0644769 A4 EP0644769 A4 EP 0644769A4 EP 93915173 A EP93915173 A EP 93915173A EP 93915173 A EP93915173 A EP 93915173A EP 0644769 A4 EP0644769 A4 EP 0644769A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- biologically active
- active peptides
- terminal substitutions
- substitutions
- terminal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/463—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from amphibians
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US89120192A | 1992-06-01 | 1992-06-01 | |
US891201 | 1992-06-01 | ||
PCT/US1993/005192 WO1993024138A1 (en) | 1992-06-01 | 1993-05-27 | Biologically active peptides having n-terminal substitutions |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0644769A1 EP0644769A1 (de) | 1995-03-29 |
EP0644769A4 true EP0644769A4 (de) | 1995-08-09 |
Family
ID=25397782
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP93915173A Ceased EP0644769A4 (de) | 1992-06-01 | 1993-05-27 | Biologisch aktive peptide mit n-terminalen substitutionen. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0644769A4 (de) |
JP (1) | JPH08500818A (de) |
AU (1) | AU674525B2 (de) |
CA (1) | CA2137087A1 (de) |
WO (1) | WO1993024138A1 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6348445B1 (en) | 1992-06-01 | 2002-02-19 | Magainin Pharmaceuticals, Inc. | Biologically active peptides with reduced toxicity in animals and a method for preparing same |
US5654274A (en) * | 1992-06-01 | 1997-08-05 | Magainin Pharmaceuticals, Inc. | Biologically active peptides having N-terminal substitutions |
US5593866A (en) * | 1992-08-21 | 1997-01-14 | The University Of British Columbia | Cationic peptides and method for production |
US5856178A (en) * | 1993-08-30 | 1999-01-05 | Utah State University | DNA cassettes for expression of lytic peptides in mammalian cells and transgenic organisms containing same |
AU693518B2 (en) * | 1994-01-18 | 1998-07-02 | Magainin Pharmaceuticals, Inc. | Ion-channel forming amphiphilic peptides having n-terminal modifications |
US5589364A (en) * | 1994-07-29 | 1996-12-31 | Magainin Pharmaceuticals Inc. | Recombinant production of biologically active peptides and proteins |
WO1996008270A2 (en) * | 1994-09-13 | 1996-03-21 | Magainin Pharmaceuticals Inc. | Method for inhibiting sexually transmitted diseases using magaining antimicrobials or squalamine compounds |
US6057291A (en) | 1995-06-02 | 2000-05-02 | University Of British Columbia | Antimicrobial cationic peptides |
ES2316154T3 (es) | 1995-08-23 | 2009-04-01 | University Of British Columbia | Peptidos cationicos antimicrobianos y procedimientos de seleccion de los mismos. |
JP2001510164A (ja) * | 1997-07-15 | 2001-07-31 | マガイニン ファーマシューティカルズ インコーポレイテッド | 動物に対する毒性を減じた生物活性ペプチドおよび同ペプチドを調製する方法。 |
NL1008139C2 (nl) * | 1998-01-27 | 1999-07-28 | Stichting Tech Wetenschapp | Antimicrobiële peptiden. |
GB9818938D0 (en) | 1998-08-28 | 1998-10-21 | Alpharma As | Bioactive peptides |
US8283315B2 (en) | 1998-08-28 | 2012-10-09 | Lytix Biopharma As | Inhibition of tumour growth |
NL1010692C2 (nl) * | 1998-12-01 | 2000-06-06 | Stichting Tech Wetenschapp | Antivirale peptiden. |
US20060228331A1 (en) | 2003-10-10 | 2006-10-12 | Novo Nordisk A/S | IL-21 Derivatives and variants |
EP2263684A1 (de) * | 2003-10-10 | 2010-12-22 | Novo Nordisk A/S | IL-21 Derivate |
US8475784B2 (en) | 2006-10-26 | 2013-07-02 | Novo Nordisk A/S | IL-21 variants |
DK2252627T3 (en) | 2008-01-24 | 2017-08-14 | Esperance Pharmaceuticals | MERGER CONSTRUCTION WITH LYTIC DOMAIN AND METHOD FOR PRODUCING AND USING SAME. |
BR112015009752A2 (pt) | 2012-10-30 | 2017-07-11 | Esperance Pharmaceuticals Inc | conjugados de anticorpo/fármaco e métodos de uso |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992001462A1 (en) * | 1990-07-19 | 1992-02-06 | The Scripps Research Institute | Amphiphilic peptide compositions and analogues thereof |
WO1992022317A1 (en) * | 1991-06-12 | 1992-12-23 | Magainin Pharmaceuticals, Inc. | Composition and treatment with biologically active peptides having c-terminal substitutions |
WO1993005802A1 (en) * | 1991-09-13 | 1993-04-01 | Magainin Pharmaceuticals Inc. | Biologically active amphiphilic peptide compositions and uses therefor |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0514464A4 (en) * | 1990-02-08 | 1993-04-28 | Magainin Sciences, Inc. | Biologically active amphiphilic peptides and method of inhibiting growth of target cells, virus or virally-infected cell |
JPH06507402A (ja) * | 1991-03-20 | 1994-08-25 | ワーナー−ランバート・コンパニー | 治療活性を有するα−置換ポリペプチド |
WO1993000359A1 (en) * | 1991-06-27 | 1993-01-07 | The Du Pont Merck Pharmaceutical Company | Modified peptides transportable into the central nervous system |
-
1993
- 1993-05-27 AU AU45258/93A patent/AU674525B2/en not_active Ceased
- 1993-05-27 JP JP6500832A patent/JPH08500818A/ja active Pending
- 1993-05-27 WO PCT/US1993/005192 patent/WO1993024138A1/en not_active Application Discontinuation
- 1993-05-27 CA CA002137087A patent/CA2137087A1/en not_active Abandoned
- 1993-05-27 EP EP93915173A patent/EP0644769A4/de not_active Ceased
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992001462A1 (en) * | 1990-07-19 | 1992-02-06 | The Scripps Research Institute | Amphiphilic peptide compositions and analogues thereof |
WO1992022317A1 (en) * | 1991-06-12 | 1992-12-23 | Magainin Pharmaceuticals, Inc. | Composition and treatment with biologically active peptides having c-terminal substitutions |
WO1993005802A1 (en) * | 1991-09-13 | 1993-04-01 | Magainin Pharmaceuticals Inc. | Biologically active amphiphilic peptide compositions and uses therefor |
Non-Patent Citations (1)
Title |
---|
See also references of WO9324138A1 * |
Also Published As
Publication number | Publication date |
---|---|
AU4525893A (en) | 1993-12-30 |
CA2137087A1 (en) | 1993-12-09 |
AU674525B2 (en) | 1997-01-02 |
JPH08500818A (ja) | 1996-01-30 |
EP0644769A1 (de) | 1995-03-29 |
WO1993024138A1 (en) | 1993-12-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19941125 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
A4 | Supplementary search report drawn up and despatched | ||
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
17Q | First examination report despatched |
Effective date: 19980401 |
|
GRAG | Despatch of communication of intention to grant |
Free format text: ORIGINAL CODE: EPIDOS AGRA |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED |
|
18R | Application refused |
Effective date: 19990509 |