EP0643586A4 - Compositions useful in diagnosis and prophylaxis of lyme disease. - Google Patents

Compositions useful in diagnosis and prophylaxis of lyme disease.

Info

Publication number
EP0643586A4
EP0643586A4 EP93914155A EP93914155A EP0643586A4 EP 0643586 A4 EP0643586 A4 EP 0643586A4 EP 93914155 A EP93914155 A EP 93914155A EP 93914155 A EP93914155 A EP 93914155A EP 0643586 A4 EP0643586 A4 EP 0643586A4
Authority
EP
European Patent Office
Prior art keywords
prophylaxis
diagnosis
compositions useful
lyme disease
lyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93914155A
Other languages
German (de)
French (fr)
Other versions
EP0643586A1 (en
Inventor
William T Golde
John T Roehrig
Thomnas Burkot
Joseph F Piesman
Barbara J B Johnson
Leonard W Mayer
Mark G Keen
Ann R Hunt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centers of Disease Control and Prevention CDC
SmithKline Beecham Corp
Original Assignee
Centers of Disease Control and Prevention CDC
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centers of Disease Control and Prevention CDC, SmithKline Beecham Corp filed Critical Centers of Disease Control and Prevention CDC
Publication of EP0643586A1 publication Critical patent/EP0643586A1/en
Publication of EP0643586A4 publication Critical patent/EP0643586A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0225—Spirochetes, e.g. Treponema, Leptospira, Borrelia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1207—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
EP93914155A 1992-05-26 1993-05-26 Compositions useful in diagnosis and prophylaxis of lyme disease. Withdrawn EP0643586A4 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US88901592A 1992-05-26 1992-05-26
US889015 1992-05-26
US94446492A 1992-09-14 1992-09-14
US944464 1992-09-14
US99289692A 1992-12-18 1992-12-18
US992896 1992-12-18
PCT/US1993/004984 WO1993024145A1 (en) 1992-05-26 1993-05-26 Compositions useful in diagnosis and prophylaxis of lyme disease

Publications (2)

Publication Number Publication Date
EP0643586A1 EP0643586A1 (en) 1995-03-22
EP0643586A4 true EP0643586A4 (en) 1996-06-26

Family

ID=27420533

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93914155A Withdrawn EP0643586A4 (en) 1992-05-26 1993-05-26 Compositions useful in diagnosis and prophylaxis of lyme disease.

Country Status (5)

Country Link
EP (1) EP0643586A4 (en)
JP (1) JPH08503194A (en)
AU (1) AU4392093A (en)
CA (1) CA2135800A1 (en)
WO (1) WO1993024145A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0880543A4 (en) * 1995-10-26 2000-08-02 Rhode Island Education Tick (ixodes scapularis) vector saliva-induced lyme disease spirochete (borrelia burgdorferi) antigens as vaccine candidates
CA2668405C (en) 2006-11-03 2015-05-05 Schering-Plough Ltd. Canine lyme disease vaccine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0506868T4 (en) * 1989-12-22 2004-04-26 Mikrogen Molekularbiol Entw Immunologically active proteins from Borrelia burgdorferi, associated with test kits and vaccine

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
E. FIKRIG ET AL.: "ROLES OF OspA, OspB, AND FLAGELLIN IN PROTECTIVE IMMUNITY TO LYME BORRELIOSIS IN LABORATORY MICE.", INFECTION AND IMMUNITY, vol. 60, no. 2, February 1992 (1992-02-01), WASHINGTON US, pages 657 - 661, XP002001270 *
J.L. BENACH ET AL.: "A MURINE IgM MONOCLONAL ANTIBODY BINDS AN ANTIGENIC DETERMINANT IN OUTER SURFACE PROTEIN A, AN IMMUNODOMINANT BASIC PROTEIN OF THE LYME DISEASE SPIROCHETE.", JOURNAL OF IMMUNOLOGY, vol. 140, no. 1, 1 January 1988 (1988-01-01), BALTIMORE US, pages 265 - 272, XP002001274 *
J.T. ROEHRIG ET AL.: "THE HAMSTER IMMUNE RESPONSE TO TICK-TRANSMITTED BORRELIA BURGDORFERI DIFFERS FROM THE RESPONSE TO NEEDLE-INOCULATED, CULTURED ORGANISMS.", JOURNAL OF IMMUNOLOGY, vol. 149, no. 11, 1 December 1992 (1992-12-01), BALTIMORE US, pages 3648 - 3653, XP002001275 *
K. HANSEN ET AL.: "IMMUNOCHEMICAL CHARACTERIZATION OF AND ISOLATION OF THE GENE FOR A BORRELIA BURGDORFERI IMMUNODOMINANT 60-KILODALTON ANTIGEN COMMON TO A WIDE RANGE OF BACTERIA.", INFECTION AND IMMUNITY, vol. 56, no. 8, August 1988 (1988-08-01), WASHINGTON US, pages 2047 - 2053, XP002001271 *
R. WALLICH ET AL.: "THE BORRELIA BURGDORFERI FLAGELLUM-ASSOCIATED 41-KILODALTON ANTIGEN (FLAGELLIN): MOLECULAR CLONING, EXPRESSION, AND AMPLIFICATION OF THE GENE.", INFECTION AND IMMUNITY, vol. 58, no. 6, June 1990 (1990-06-01), WASHINGTON US, pages 1711 - 1719, XP002001272 *
R.S. LANE ET AL.: "ANTIGENIC CHARACTERISTICS OF BORRELIA BURGDORFERI ISOLATES FROM IXODID TICKS IN CALIFORNIA.", JOURNAL OF CLINICAL MICROBIOLOGY, vol. 27, no. 10, October 1989 (1989-10-01), WASHINGTON, D.C., US, pages 2344 - 2349, XP000568737 *
See also references of WO9324145A1 *
V.G. BUNDOC ET AL.: "CLONAL POLYMORPHISMS OF THE OUTER MEMBRANE PROTEIN OspB OF BORRELIA BURGDORFERI.", INFECTION AND IMMUNITY, vol. 57, no. 9, September 1989 (1989-09-01), WASHINGTON US, pages 2733 - 2741, XP002001273 *
W.T. GOLDE ET AL.: "THE MAJOR HISTOCOMPATIBILITY COMPLEX-RESTRICTED RESPONSE OF RECOMBINANT INBRED STRAINS OF MICE TO NATURAL TICK TRANSMISSION OF BORRELIA BURGDORFERI.", THE JOURNAL OF EXPERIMENTAL MEDICINE, vol. 177, no. 1, January 1993 (1993-01-01), NEW YORK, N.Y., US, pages 9 - 17, XP000568811 *

Also Published As

Publication number Publication date
WO1993024145A1 (en) 1993-12-09
JPH08503194A (en) 1996-04-09
EP0643586A1 (en) 1995-03-22
AU4392093A (en) 1993-12-30
CA2135800A1 (en) 1993-12-09

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 19941201

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Effective date: 19960521