EP0626972A4 - Process of preparing 3-acylandrostadienes. - Google Patents

Process of preparing 3-acylandrostadienes.

Info

Publication number
EP0626972A4
EP0626972A4 EP93904948A EP93904948A EP0626972A4 EP 0626972 A4 EP0626972 A4 EP 0626972A4 EP 93904948 A EP93904948 A EP 93904948A EP 93904948 A EP93904948 A EP 93904948A EP 0626972 A4 EP0626972 A4 EP 0626972A4
Authority
EP
European Patent Office
Prior art keywords
acylandrostadienes
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93904948A
Other languages
English (en)
Other versions
EP0626972A1 (en
Inventor
Neil Howard Baine
Michael A. Mcguire
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP0626972A1 publication Critical patent/EP0626972A1/en
Publication of EP0626972A4 publication Critical patent/EP0626972A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0066—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by a carbon atom forming part of an amide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP93904948A 1992-02-07 1993-02-05 Process of preparing 3-acylandrostadienes. Withdrawn EP0626972A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83227992A 1992-02-07 1992-02-07
US832279 1992-02-07
PCT/US1993/001071 WO1993016098A1 (en) 1992-02-07 1993-02-05 Process of preparing 3-acylandrostadienes

Publications (2)

Publication Number Publication Date
EP0626972A1 EP0626972A1 (en) 1994-12-07
EP0626972A4 true EP0626972A4 (en) 1995-01-04

Family

ID=25261205

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93904948A Withdrawn EP0626972A4 (en) 1992-02-07 1993-02-05 Process of preparing 3-acylandrostadienes.

Country Status (13)

Country Link
EP (1) EP0626972A4 (lt)
JP (1) JPH07505618A (lt)
KR (1) KR950700320A (lt)
CN (1) CN1078474A (lt)
AU (1) AU3612893A (lt)
CA (1) CA2129347A1 (lt)
IL (1) IL104601A0 (lt)
MA (1) MA22787A1 (lt)
MX (1) MX9300677A (lt)
SI (1) SI9300067A (lt)
TW (1) TW241266B (lt)
WO (1) WO1993016098A1 (lt)
ZA (1) ZA93802B (lt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL104602A (en) * 1992-02-07 1997-07-13 Smithkline Beecham Corp Process for the preparation of 3-carbonylandrostadiene- 17-carboxamides and intermediates for this process
US5641765A (en) * 1992-11-18 1997-06-24 Smithkline Beecham Corporation 17-αand 17-βsubstituted acyl-3-carboxy-3,5-dienes and use in inhibiting 5-α-reductase
US5683995A (en) * 1992-11-18 1997-11-04 Smithkline Beecham Corporation 17 substituted acyl-3-carboxy 3,5-diene steroidals as α-reductase inhibitors

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0465141A2 (en) * 1990-06-28 1992-01-08 Merck & Co. Inc. N-monosubstituted adamantyl/norbornanyl 17beta-carbamides of3-carboxy-androst-3,5-dienes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946834A (en) * 1988-12-23 1990-08-07 Smithkline Beecham Corporation Phosphonic acid substituted steroids as steroid 5α-reductase inhibitors
US5032586A (en) * 1989-08-24 1991-07-16 Smithkline Beecham Corporation 7-keto or hydroxy 3,5-diene steroids as inhibitors of steroid 5-alpha reductase

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0465141A2 (en) * 1990-06-28 1992-01-08 Merck & Co. Inc. N-monosubstituted adamantyl/norbornanyl 17beta-carbamides of3-carboxy-androst-3,5-dienes

Also Published As

Publication number Publication date
JPH07505618A (ja) 1995-06-22
WO1993016098A1 (en) 1993-08-19
CN1078474A (zh) 1993-11-17
TW241266B (lt) 1995-02-21
ZA93802B (en) 1993-11-05
AU3612893A (en) 1993-09-03
SI9300067A (en) 1993-09-30
MX9300677A (es) 1994-07-29
KR950700320A (ko) 1995-01-16
CA2129347A1 (en) 1993-08-19
MA22787A1 (fr) 1993-10-01
EP0626972A1 (en) 1994-12-07
IL104601A0 (en) 1993-07-08

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 19940729

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Ipc: C07J 41/00

A4 Supplementary search report drawn up and despatched

Effective date: 19941122

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Effective date: 19960903