EP0608648B1 - Hochdosierte Vitamine A-Zusammensetzungen - Google Patents

Hochdosierte Vitamine A-Zusammensetzungen Download PDF

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Publication number
EP0608648B1
EP0608648B1 EP93403121A EP93403121A EP0608648B1 EP 0608648 B1 EP0608648 B1 EP 0608648B1 EP 93403121 A EP93403121 A EP 93403121A EP 93403121 A EP93403121 A EP 93403121A EP 0608648 B1 EP0608648 B1 EP 0608648B1
Authority
EP
European Patent Office
Prior art keywords
vitamin
days
compositions
therapeutic composition
high dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP93403121A
Other languages
English (en)
French (fr)
Other versions
EP0608648A1 (de
Inventor
Georges Serge Grimberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP0608648A1 publication Critical patent/EP0608648A1/de
Application granted granted Critical
Publication of EP0608648B1 publication Critical patent/EP0608648B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/062—Ascomycota
    • A61K36/066—Clavicipitaceae

Definitions

  • compositions formed of combinations of vitamins A and of various active principles having a therapeutic activity with a view to alleviating the disorders occurring in the ENT sphere.
  • the medicament described in patent FR-A-2 228 470 contains vitamin A, sulfur, cystine and yeast. His prescription is 900,000 IU of vitamin A for a fortnight. This therapy recommended fifteen to twenty days a month for three months makes the patient absorb a quantity of vitamin A of 2,700,000 IU at least.
  • FR-A-2 647 784 describes a new therapeutic composition of vitamin A but at a physiological dose and it does not meet the conditions necessary for the treatment of acute or influenza rhinitis.
  • the present invention contains a high dose of vitamin A which is two to three times the dose of the medicament described in FR-A-2 228 470 and twenty to thirty times greater than the medicament described in FR-A-2 647 784 and the duration of treatment is three to four days or it follows that there is no risk and that rhinitis heals in three or four days.
  • compositions which also contain vitamin A and mention may be made, for example, of the composition according to FR-A-2 431 863.
  • a dose of this composition contains a relatively small proportion of vitamin A and is associated with a vitamin B complex because this composition can be used in dermatology as shown by the various examples cited in the document.
  • vitamin A is also known in the treatment of leukemia and one can quote for this purpose the review "European Journal of Haemathology” which, in volume 40 No 5 of May 1988, pages 460-465 shows the use of vitamin A combined with cytarabine (chemotherapy).
  • the use of vitamin A is known in the treatment of breast cancer and one can cite on this subject the journal “The Journal of Cancer Research and Clinical Oncology” which, in volume 116 No 5 of 1990, pages 503- 506 shows the use of vitamin A combined with tamoxifen (anti-estrogen used in hormone therapy) for the treatment of advanced breast cancer.
  • the twenty patients in the first group treated with the new drug formula are the only ones to have been cured in four days.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Claims (2)

  1. Neue, therapeutische Zusammensetzung, welche auf dem Gebiet der Hals-Nasen-Ohrenheilkunde auftretenden Störungen abhilft und eine drei- oder viertägige Behandlung ermöglicht, dadurch gekennzeichnet, daß sie eine Dosis 40 000 IE bis 60 000 IE Vitamin A 217,8 mg Basis-L. Cystine (L. Cystine base) 66 mg gewaschene Schwefelblume 232,2 mg totes Gärungsmittel (Levure morte)
    enthält.
  2. Neue, therapeutische Zusammensetzung nach Anspruch 1, dadurch gekennzeichnet, daß das tote Gärungsmittel eine Hefe der Gattung Saccharomyces ist.
EP93403121A 1993-01-28 1993-12-21 Hochdosierte Vitamine A-Zusammensetzungen Expired - Lifetime EP0608648B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9300861A FR2700695B1 (fr) 1993-01-28 1993-01-28 Composition thérapeutique nouvelle remédiant aux désordres survenant dans la sphère ORL.
FR9300861 1993-01-28

Publications (2)

Publication Number Publication Date
EP0608648A1 EP0608648A1 (de) 1994-08-03
EP0608648B1 true EP0608648B1 (de) 1997-05-21

Family

ID=9443444

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93403121A Expired - Lifetime EP0608648B1 (de) 1993-01-28 1993-12-21 Hochdosierte Vitamine A-Zusammensetzungen

Country Status (11)

Country Link
US (1) US5510111A (de)
EP (1) EP0608648B1 (de)
AT (1) ATE153241T1 (de)
CA (1) CA2112501C (de)
DE (1) DE69310889T2 (de)
DK (1) DK0608648T3 (de)
ES (1) ES2101982T3 (de)
FR (1) FR2700695B1 (de)
GR (1) GR3024253T3 (de)
IL (1) IL108191A (de)
MA (1) MA23098A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6187764B1 (en) * 1997-05-05 2001-02-13 Angelina Pinal Buttz A and D vitamins and their metabolites: A new treatment for seasonal allergic rhinitis and atopy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2431863A1 (fr) * 1978-07-24 1980-02-22 Martin Henri Nouveau medicament a base de vitamine a, de vitamines b, de soufre et de substances biologiques
FR2647784B1 (fr) * 1989-06-06 1991-10-04 Grimberg Georges Association de vitamine a a dose physiologique et de differents principes actifs ayant une activite therapeutique

Also Published As

Publication number Publication date
EP0608648A1 (de) 1994-08-03
IL108191A0 (en) 1994-04-12
ES2101982T3 (es) 1997-07-16
US5510111A (en) 1996-04-23
FR2700695B1 (fr) 1995-04-07
GR3024253T3 (en) 1997-10-31
IL108191A (en) 1998-08-16
CA2112501C (fr) 1996-08-13
FR2700695A1 (fr) 1994-07-29
DK0608648T3 (da) 1997-06-16
DE69310889T2 (de) 1998-01-29
CA2112501A1 (fr) 1994-07-29
MA23098A1 (fr) 1994-10-01
DE69310889D1 (de) 1997-06-26
ATE153241T1 (de) 1997-06-15

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