EP0606427A1 - Appareil de traitement aux micro-ondes - Google Patents

Appareil de traitement aux micro-ondes

Info

Publication number
EP0606427A1
EP0606427A1 EP93914910A EP93914910A EP0606427A1 EP 0606427 A1 EP0606427 A1 EP 0606427A1 EP 93914910 A EP93914910 A EP 93914910A EP 93914910 A EP93914910 A EP 93914910A EP 0606427 A1 EP0606427 A1 EP 0606427A1
Authority
EP
European Patent Office
Prior art keywords
support structure
antenna
assembly
probe
catheter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93914910A
Other languages
German (de)
English (en)
Inventor
Alan Thompson
Arron Grist
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MICROWAVE ENGINEERING DESIGNS Ltd
Original Assignee
MICROWAVE ENGINEERING DESIGNS Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MICROWAVE ENGINEERING DESIGNS Ltd filed Critical MICROWAVE ENGINEERING DESIGNS Ltd
Publication of EP0606427A1 publication Critical patent/EP0606427A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • A61B2018/1861—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves with an instrument inserted into a body lumen or cavity, e.g. a catheter

Definitions

  • This invention relates to microwave treatment apparatus, particularly a catheter and to a reusable applicator assembly for use with a disposable catheter.
  • microwave heating is known for the treatment of both benign and malignant conditions.
  • disorders of the prostate may be treated by means of a microwave applicator contained in or carried upon a transurethral catheter - see for example European patent specifications numbers 0246176, 045 535 and 0462302.
  • transurethral and other small-diameter microwave catheters suffer from a number of disadvantages, amongst which are that they are not re-usable without sterilisation, and that it is difficult to position the microwave applicator at the optimum location for most effective and safest treatment.
  • the latter problem is particularly significant with transurethral microwave catheters; incorrect location of the applicator may result in injury to the lower urethral sphincter which could render the patient incontinent.
  • the present invention in its several aspects has amongst its objects the provision of a microwave applicator in a catheter or a reusable assembly therefor which avoids one or both of these prior-art disadvantages.
  • the invention provides an assembly for insertion in a probe to form a microwave thermal treatment device, comprising a microwave antenna and support structure for locating the antenna within the probe near a distal end thereof, the support structure comprising means for engaging a proximal end of the probe and adjustment means for effecting controlled relative movement between the engaging means and the support structure whereby to adjust the longitudinal position of the antenna within the probe.
  • the invention provides apparatus for microwave thermal treatment comprising a probe, a microwave antenna support structure for locating the antenna within the probe near a distal end thereof, the support structure comprising means engaging the probe at a proximal end thereof and adjustment means for effecting controlled relative movement between the engaging means and the support structure whereby to adjust the longitudinal position of the antenna relative to the probe.
  • this invention provides a reusable microwave applicator assembly for use in thermal treatment and adapted for use with a disposable catheter, the assembly comprising a microwave antenna, support structure for removably locating the antenna in the interior of the catheter near a distal end thereof to be introduced into a patient's body, said support structure comprising a duct which together with the interior of the catheter provides a means of circulating coolant through the catheter externally of the support structure.
  • the support structure may comprise at least one tube forming said duct, and a sleeve wherein the at least one tube and an electrical conductor for the antenna are contained.
  • the antenna may be of helical form, and the said duct may extend at least to the tip of the antenna.
  • a ridged plug for engaging the proximal end of the catheter to form a liquid-tight seal therewith.
  • the adjustment means may comprise a member within which the support structure is longitudinally movable, and means for engaging the member to constrain the support structure against movement, the member being connected or connectable to the catheter or probe.
  • the ridged plug may be carried by the member.
  • the invention also provides microwave thermal treatment equipment comprising an applicator assembly or apparatus as set forth above, a source of microwave frequency electric power and means for operatively connecting said source to the assembly or apparatus.
  • Figure 1 shows a reusable microwave applicator assembly according to the invention
  • Figure 2 is an enlarged and partially disassembled view of the assembly of Figure 1;
  • Figure 3 and 4 are sections through Figure 2 on lines 3"3 and 4-4 respectively;
  • Figure 5 is a side elevation of the assembly of Figure 2
  • Figure 6 is an enlarged view of part of the assembly of Figure 1.
  • the apparatus comprises a probe, specifically a transurethral catheter 10 having a blind distal end 12 (ie having no drainage holes) and a balloon 14, inflatable in a conventional manner via an inflation duct from an inflator connector 16.
  • a microwave applicator comprises a transmitting antenna 17 formed of helically wound copper tape, dimensioned as is known in the art to operate at an allocated medical microwave frequency (eg 434 MHz or 904/915 MHz or other appropriate frequency) .
  • an allocated medical microwave frequency eg 434 MHz or 904/915 MHz or other appropriate frequency
  • the antenna 17 is carried on a support structure 18 consisting of a microwave coaxial conductor 20 and two ptfe tubes 22,24 arranged in a triangular configuration ( Figure 4) and encased within a heat-shrink sleeve 26.
  • the sleeve 26 extends to the antenna 17 as shown in Figure 4; it is shown partially removed in Figure 1 only for reasons of clarity.
  • the outer casing of the conductor 20 is removed and the inner screened lead 28 is connected to the adjacent end of the antenna.
  • the screen lead 30 is sleeved in a piece of ptfe tube 31 and together with the pipes 22,24 are encased in a further short piece of heat shrink sleeve 32 on which the copper tape forming the antenna 17 is wound.
  • the support structure 18 extends back down the catheter to its proximal end 34 and through a tube 36.
  • the bore of the tube 36 is significantly larger than the diameter of the structure 20, so that a flow of coolant (eg deionized water) can also pass through the bore as hereafter described.
  • the tube 36 has a conical ridged plug 38 which can be inserted in the correspondingly-shaped proximal end 3 of the catheter 10 to form a liquid-tight seal.
  • the tube 36 in itself telescopically received in a tubular portion 40 of a manifold 42 within which the heat-shrink sleeve 26 terminates; (the sleeve is again shown foreshortened in Figure 1 for clarity).
  • the microwave conductor 20 is taken out through the manifold 42 to a suitable microwave-frequency connector 44.
  • the connector may alternatively be mounted in the manifold 42.
  • the pipes 22,24 are taken through the tube 40 to a cooling water inlet connection 46.
  • a cooling water outlet connection 48 communicates via a pipe 0 with the interior of the tube 40 and thus with the tube 36, permitting cooling water to flow out of the interior of the catheter to the outlet 48.
  • the conductor 20 and the tubes 22,24 are potted with epoxy resin within the manifold 42 in a conventional manner, and thus are firmly fixed therein.
  • the end of the tubular portion 40 carries a clamping nut 54 on a threaded portion (not shown) together with a rubber sealing washer between the nut and the end of the tube 40.
  • the washer when axially compressed by the nut 54 expands radially inwardly whereby to grip the tube 36 within it so that the parts 18, 36 and 42 cannot move longitudinally relative to each other.
  • the antenna 17 is thereby fixed longitudinally in the catheter when the clamping nut is tightened.
  • An additional separate blind conduit (not shown) preferably is provided in the catheter 10 to contain a thermocouple or other temperature sensor adjacent the antenna, together with its electrical connection, so that the temperature of the tissue in contact with the catheter during microwave treatment may be monitored.
  • the additional conduit is disposed along the outside of the catheter 10.
  • the re-usable assembly consisting of the antenna 17, support structure 18, tube 36 and manifold etc 40,42 are inserted in the disposable catheter 10, the latter having been sterilised.
  • the catheter is introduced into the patient's urethra until the balloon portion 14 enters his bladder.
  • the balloon is then inflated in the conventional manner to retain the catheter in position.
  • the catheter has been so inserted, the approximate position of the patient's prostate is shown dotted at 56, and that of the lower urethral sphincter sybolically at 58.
  • the position of the antenna relative to these organs is determined by any suitable technique eg ultrasonic imaging, and any necessary adjustment to its position is made by loosening the clamping nut 4 and sliding the manifold 42 and the support structure 18 relative to the tube 36 which is fixed in the proximal end of the catheter 10.
  • the clamping nut is tightened.
  • the necessary water connections 46,48 and the thermocouple connection are completed.
  • the antenna 17 is connected via connector 44 to a source of microwave power (not shown) of appropriate authorised medical frequency suited to the dimensions of the antenna.
  • the catheter may first be introduced into the urethra and the position of the postate and lower sphincter found relative to the end of the catheter by any suitable means eg ultrasound or by a fibre-optic probe introduced into the catheter.
  • the correct length of insertion of the structure 18 and antenna 17 can then be determined, and the telescopic tubes 36,40 adjusted accordingly.
  • a graduated scale may be provided on the tube 36 for this purpose.
  • the antenna is then introduced into the catheter and the plug 38 secured in the proximal end 34 thereof.
  • cooling water is passed along the tubes 22,24 and returns down the interior of the catheter to the outlet 48.
  • the distal ends of the tubes 22,24 may be bent as shown at 60 ( Figures 1 and 6) so as to impart increased turbulence to the water issuing from them, improving heat transfer from the walls of the catheter and thereby from the tissue in contact therewith.
  • the tubes 22,24 extend at least to the end of the antenna, and preferably slightly beyond towards the end of the catheter.
  • the catheter Upon completion of treatment the catheter is withdrawn from the patient and discarded, the applicator assembly being retained for re-use.
  • tubes 22,24 may be replaced by a single tube or by several tubes.
  • two tubes have the advantage of producing a conveniently-shaped structure 18 with the conductor 20, of approximately triangular section, as can be seen from Figure 4.
  • transurethral catheter Although described in the context of a transurethral catheter it will be understood that the invention is applicable also in other catheters or probes for insertion into the body.

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Electromagnetism (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Otolaryngology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiation-Therapy Devices (AREA)
  • Surgical Instruments (AREA)

Abstract

Appareil de traitement thermique aux micro-ondes comportant une sonde, une structure support de l'antenne micro-ondes permettant de placer ladite antenne à l'intérieur de la sonde, près de son extrémité distale. La structure support comprend des moyens de mise en contact avec la sonde à son extrémité proximale, ainsi que des moyens de réglage pour effectuer un mouvement relatif contrôlé entre les moyens de mise en contact et la structure support, permettant ainsi de régler la position longitudinale de l'antenne par rapport à la sonde. La structure support comprend également une gaine qui, avec l'intérieur d'un cathéter jetable formant la sonde, permet de faire circuler du liquide de refroidissement à travers le cathéter à l'extérieur de ladite structure.
EP93914910A 1992-07-15 1993-07-09 Appareil de traitement aux micro-ondes Withdrawn EP0606427A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB929215042A GB9215042D0 (en) 1992-07-15 1992-07-15 Microwave treatment apparatus
GB9215042 1992-07-15
PCT/GB1993/001439 WO1994002204A1 (fr) 1992-07-15 1993-07-09 Appareil de traitement aux micro-ondes

Publications (1)

Publication Number Publication Date
EP0606427A1 true EP0606427A1 (fr) 1994-07-20

Family

ID=10718752

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93914910A Withdrawn EP0606427A1 (fr) 1992-07-15 1993-07-09 Appareil de traitement aux micro-ondes

Country Status (4)

Country Link
EP (1) EP0606427A1 (fr)
AU (1) AU4511493A (fr)
GB (1) GB9215042D0 (fr)
WO (1) WO1994002204A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5628770A (en) * 1995-06-06 1997-05-13 Urologix, Inc. Devices for transurethral thermal therapy
US5788692A (en) * 1995-06-30 1998-08-04 Fidus Medical Technology Corporation Mapping ablation catheter
US5938692A (en) * 1996-03-26 1999-08-17 Urologix, Inc. Voltage controlled variable tuning antenna
US5800486A (en) * 1996-06-17 1998-09-01 Urologix, Inc. Device for transurethral thermal therapy with cooling balloon
US6245062B1 (en) 1998-10-23 2001-06-12 Afx, Inc. Directional reflector shield assembly for a microwave ablation instrument
US6122551A (en) * 1998-12-11 2000-09-19 Urologix, Inc. Method of controlling thermal therapy
US6272384B1 (en) 1999-05-27 2001-08-07 Urologix, Inc. Microwave therapy apparatus
US6673068B1 (en) 2000-04-12 2004-01-06 Afx, Inc. Electrode arrangement for use in a medical instrument
US20020087151A1 (en) 2000-12-29 2002-07-04 Afx, Inc. Tissue ablation apparatus with a sliding ablation instrument and method
WO2003070298A2 (fr) 2002-02-15 2003-08-28 Celsion Corporation Procede et appareil de traitement de tissus proches d'un conduit corporel par thermocompression et administration de medicaments
US10076384B2 (en) 2013-03-08 2018-09-18 Symple Surgical, Inc. Balloon catheter apparatus with microwave emitter

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4800899A (en) * 1984-10-22 1989-01-31 Microthermia Technology, Inc. Apparatus for destroying cells in tumors and the like
IL78755A0 (en) * 1986-05-12 1986-08-31 Biodan Medical Systems Ltd Applicator for insertion into a body opening for medical purposes
US4795434A (en) * 1987-09-10 1989-01-03 C. R. Bard, Inc. Apparatus for positioning a sensor in vivo
JPH0265941U (fr) * 1988-11-07 1990-05-17
WO1992010932A1 (fr) * 1990-12-17 1992-07-09 Microwave Medical Systems, Inc. Sonde therapeutique servant a emettre des micro-ondes et des rayonnements nucleaires

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9402204A1 *

Also Published As

Publication number Publication date
AU4511493A (en) 1994-02-14
GB9215042D0 (en) 1992-08-26
WO1994002204A1 (fr) 1994-02-03

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