EP0604624A4 - Multimeric forms of human rhinovirus receptor protein. - Google Patents

Multimeric forms of human rhinovirus receptor protein.

Info

Publication number
EP0604624A4
EP0604624A4 EP93915452A EP93915452A EP0604624A4 EP 0604624 A4 EP0604624 A4 EP 0604624A4 EP 93915452 A EP93915452 A EP 93915452A EP 93915452 A EP93915452 A EP 93915452A EP 0604624 A4 EP0604624 A4 EP 0604624A4
Authority
EP
European Patent Office
Prior art keywords
receptor protein
human rhinovirus
multimeric forms
rhinovirus receptor
multimeric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93915452A
Other languages
German (de)
French (fr)
Other versions
EP0604624A1 (en
Inventor
Jeffrey M Greve
Alan Mcclelland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Inc filed Critical Miles Inc
Publication of EP0604624A1 publication Critical patent/EP0604624A1/en
Publication of EP0604624A4 publication Critical patent/EP0604624A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/085—Picornaviridae, e.g. coxsackie virus, echovirus, enterovirus
    • C07K14/095—Rhinovirus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C07K17/08—Peptides being immobilised on, or in, an organic carrier the carrier being a synthetic polymer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP93915452A 1992-06-22 1993-06-22 Multimeric forms of human rhinovirus receptor protein. Withdrawn EP0604624A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US90306992A 1992-06-22 1992-06-22
US903069 1992-06-22
PCT/US1993/005972 WO1994000485A1 (en) 1992-06-22 1993-06-22 Multimeric forms of human rhinovirus receptor protein

Publications (2)

Publication Number Publication Date
EP0604624A1 EP0604624A1 (en) 1994-07-06
EP0604624A4 true EP0604624A4 (en) 1997-03-12

Family

ID=25416893

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93915452A Withdrawn EP0604624A4 (en) 1992-06-22 1993-06-22 Multimeric forms of human rhinovirus receptor protein.

Country Status (10)

Country Link
EP (1) EP0604624A4 (en)
JP (1) JPH06510208A (en)
KR (1) KR950702576A (en)
AU (1) AU675441B2 (en)
CA (1) CA2116109A1 (en)
FI (1) FI946006A0 (en)
HU (1) HUT75827A (en)
NO (1) NO944966D0 (en)
RU (1) RU94046450A (en)
WO (1) WO1994000485A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6514936B1 (en) 1988-09-01 2003-02-04 Bayer Corporation Antiviral methods using human rhinovirus receptor (ICAM-1)
ES2141076T3 (en) 1988-09-01 2000-03-16 Bayer Ag HUMAN RHINOVIRUS RECEPTOR PROTEIN INHIBITING VIRUS INFECTIVITY.
GB9414966D0 (en) * 1994-07-26 1994-09-14 Danbiosyst Uk Pharmaceutical compositions for the nasal administration of antiviral agents
GB9520641D0 (en) * 1995-10-10 1995-12-13 Medical Res Council Improvements in or relating to protection against intracellular infection
US6391452B1 (en) 1997-07-18 2002-05-21 Bayer Corporation Compositions for nasal drug delivery, methods of making same, and methods of removing residual solvent from pharmaceutical preparations
EA034861B1 (en) * 2012-03-31 2020-03-30 Р-Фарм Интернешнл, Ооо (Общество С Ограниченной Ответственностью) Osteoprotegerin derived composition and method of use thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0365837A2 (en) * 1988-09-28 1990-05-02 Dana Farber Cancer Institute Intercellular adhesion molecules, and their binding ligands
EP0387701A1 (en) * 1989-03-09 1990-09-19 Boehringer Ingelheim Pharmaceuticals Inc. Use of intercellular adhesion molecules, and their binding ligands in the treatment of asthma
EP0468257A1 (en) * 1990-07-20 1992-01-29 Bayer Corporation Multimeric form of human rhinovirus receptor protein

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0365837A2 (en) * 1988-09-28 1990-05-02 Dana Farber Cancer Institute Intercellular adhesion molecules, and their binding ligands
EP0387701A1 (en) * 1989-03-09 1990-09-19 Boehringer Ingelheim Pharmaceuticals Inc. Use of intercellular adhesion molecules, and their binding ligands in the treatment of asthma
EP0468257A1 (en) * 1990-07-20 1992-01-29 Bayer Corporation Multimeric form of human rhinovirus receptor protein

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GREVE J. M. ET AL.,: "Mechanism of receptor-mediated rhinovirus neutralization defined by two soluble forms of ICAM-1", J. VIROLOGY, vol. 65, November 1991 (1991-11-01), pages 6015 - 6023, XP000615280 *
MARTIN S. ET AL.,: "Erfolgreiche Blockade von Rhinovirusinfektionen durch ICAM-1-Immunglobulinchimäre in vitro", MEDIZINISCHE KLINIK, vol. 88, no. 4, 15 April 1993 (1993-04-15), pages 193 - 197, XP000615274 *
See also references of WO9400485A1 *

Also Published As

Publication number Publication date
NO944966L (en) 1994-12-21
FI946006A (en) 1994-12-21
CA2116109A1 (en) 1994-01-06
WO1994000485A1 (en) 1994-01-06
AU4543293A (en) 1994-01-24
FI946006A0 (en) 1994-12-21
NO944966D0 (en) 1994-12-21
KR950702576A (en) 1995-07-29
AU675441B2 (en) 1997-02-06
EP0604624A1 (en) 1994-07-06
RU94046450A (en) 1996-10-10
HUT75827A (en) 1997-05-28
JPH06510208A (en) 1994-11-17
HU9403720D0 (en) 1995-02-28

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Legal Events

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Owner name: BAYER CORPORATION

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Owner name: BAYER CORPORATION

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Effective date: 19970127

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Effective date: 20011222