EP0572508A4 - Acide nucleique codant le substrat-1 recepteur d'insuline (irs-1), proteine d'irs-1, maladies et therapie associees au metabolisme de l'irs-1. - Google Patents

Acide nucleique codant le substrat-1 recepteur d'insuline (irs-1), proteine d'irs-1, maladies et therapie associees au metabolisme de l'irs-1.

Info

Publication number
EP0572508A4
EP0572508A4 EP92906151A EP92906151A EP0572508A4 EP 0572508 A4 EP0572508 A4 EP 0572508A4 EP 92906151 A EP92906151 A EP 92906151A EP 92906151 A EP92906151 A EP 92906151A EP 0572508 A4 EP0572508 A4 EP 0572508A4
Authority
EP
European Patent Office
Prior art keywords
irs
metabolism
diseases
protein
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP92906151A
Other languages
German (de)
English (en)
Other versions
EP0572508A1 (fr
Inventor
C Ronald Kahn
Morris F White
Paul Louis Rothenberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Joslin Diabetes Center Inc
Original Assignee
Joslin Diabetes Center Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Joslin Diabetes Center Inc filed Critical Joslin Diabetes Center Inc
Publication of EP0572508A1 publication Critical patent/EP0572508A1/fr
Publication of EP0572508A4 publication Critical patent/EP0572508A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EP92906151A 1991-01-18 1992-01-17 Acide nucleique codant le substrat-1 recepteur d'insuline (irs-1), proteine d'irs-1, maladies et therapie associees au metabolisme de l'irs-1. Withdrawn EP0572508A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US643982 1984-08-24
US64398291A 1991-01-18 1991-01-18

Publications (2)

Publication Number Publication Date
EP0572508A1 EP0572508A1 (fr) 1993-12-08
EP0572508A4 true EP0572508A4 (fr) 1995-03-29

Family

ID=24582950

Family Applications (1)

Application Number Title Priority Date Filing Date
EP92906151A Withdrawn EP0572508A4 (fr) 1991-01-18 1992-01-17 Acide nucleique codant le substrat-1 recepteur d'insuline (irs-1), proteine d'irs-1, maladies et therapie associees au metabolisme de l'irs-1.

Country Status (2)

Country Link
EP (1) EP0572508A4 (fr)
WO (1) WO1992013083A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2264481B (en) * 1992-02-26 1996-06-19 Samsonite Corp Luggage case
WO1994029345A1 (fr) * 1993-06-10 1994-12-22 Novo Nordisk A/S Adn mutant codant le substrat 1 du recepteur d'insuline
US5861266A (en) * 1994-02-28 1999-01-19 New York University Treatment of diabetes mellitus and insulin receptor signal transduction
US5858701A (en) * 1994-10-03 1999-01-12 Joslin Diabetes Center, Inc. DNA encoding an insulin receptor substrate
US5891674A (en) * 1997-06-19 1999-04-06 Incyte Pharmaceuticals, Inc. Insulin receptor tyrosine kinase substrate
DE19739360C2 (de) * 1997-09-09 1999-12-09 Deutsches Krebsforsch Verfahren zur Diagnose von frühen Krebsvorstufen der Leber und Niere
US6525185B1 (en) 1998-05-07 2003-02-25 Affymetrix, Inc. Polymorphisms associated with hypertension
FR2826010B1 (fr) * 2001-06-14 2005-02-25 Mahmood Salman Al Oligonucleotides antisens capables d'inhiber la formation des tubes capillaires par les cellules endotheliales
US9682144B2 (en) 2011-06-30 2017-06-20 Gene Signal International, Sa Composition comprising inhibitors of IRS-1 and of VEGF
US10052343B1 (en) 2017-02-03 2018-08-21 Gene Signal International Sa Sterile formulation comprising a stable phosphorothioate oligonucleotide
CN111662369B (zh) * 2020-07-10 2022-06-03 华中农业大学 一种中黑盲蝽insulin receptor substrate 1基因及其应用

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MORRIS F. WHITE ET AL.: "Characterization of an endogenous substrate of the insulin receptor in cultured cells", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 262, no. 20, 15 July 1987 (1987-07-15), BALTIMORE, MD US, pages 9769 - 9777 *
See also references of WO9213083A1 *

Also Published As

Publication number Publication date
EP0572508A1 (fr) 1993-12-08
WO1992013083A1 (fr) 1992-08-06

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