EP0571554A1 - Grundstruktur immunogener polypeptide mit epitopen für hcv, antikörper, polynukleotidsequenzen, impfstoffe und verfahren - Google Patents

Grundstruktur immunogener polypeptide mit epitopen für hcv, antikörper, polynukleotidsequenzen, impfstoffe und verfahren

Info

Publication number
EP0571554A1
EP0571554A1 EP92907699A EP92907699A EP0571554A1 EP 0571554 A1 EP0571554 A1 EP 0571554A1 EP 92907699 A EP92907699 A EP 92907699A EP 92907699 A EP92907699 A EP 92907699A EP 0571554 A1 EP0571554 A1 EP 0571554A1
Authority
EP
European Patent Office
Prior art keywords
recited
hcv
polypeptide
antibody
basic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP92907699A
Other languages
English (en)
French (fr)
Inventor
Girish J. Kotwal
Bahige M. Baroudy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gamble James N Institute of Medical Research
Original Assignee
Gamble James N Institute of Medical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gamble James N Institute of Medical Research filed Critical Gamble James N Institute of Medical Research
Publication of EP0571554A1 publication Critical patent/EP0571554A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • C07K16/109Hepatitis C virus; Hepatitis G virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
EP92907699A 1991-01-14 1992-01-14 Grundstruktur immunogener polypeptide mit epitopen für hcv, antikörper, polynukleotidsequenzen, impfstoffe und verfahren Withdrawn EP0571554A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63980991A 1991-01-14 1991-01-14
US639809 1991-01-14

Publications (1)

Publication Number Publication Date
EP0571554A1 true EP0571554A1 (de) 1993-12-01

Family

ID=24565635

Family Applications (1)

Application Number Title Priority Date Filing Date
EP92907699A Withdrawn EP0571554A1 (de) 1991-01-14 1992-01-14 Grundstruktur immunogener polypeptide mit epitopen für hcv, antikörper, polynukleotidsequenzen, impfstoffe und verfahren

Country Status (3)

Country Link
EP (1) EP0571554A1 (de)
AU (1) AU1459792A (de)
WO (1) WO1992012992A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9105871D0 (en) * 1991-03-20 1991-05-08 Inst Cientifico Tecnol Navarra Synthetic peptides
DE4209215A1 (de) * 1991-07-04 1993-01-07 Boehringer Mannheim Gmbh Hcv peptidantigene und verfahren zur bestimmung von hcv
CA2120340A1 (en) * 1991-10-02 1994-04-15 Kaichiro Ishibashi Reagents for testing for hepatitis c and method of testing for the same
DE4240980A1 (de) * 1992-08-07 1994-02-10 Boehringer Mannheim Gmbh HCV Peptidantigene und Verfahren zur Bestimmung von HCV
JPH06311885A (ja) * 1992-08-25 1994-11-08 Mitsubishi Kasei Corp C型肝炎ウイルス遺伝子に相補的なアンチセンス化合物
US6174868B1 (en) * 1992-09-10 2001-01-16 Isis Pharmaceuticals, Inc. Compositions and methods for treatment of hepatitis C virus-associated diseases
WO1994005813A1 (en) * 1992-09-10 1994-03-17 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Compositions and methods for treatment of hepatitis c virus-associated diseases
JPH10503364A (ja) * 1994-05-10 1998-03-31 ザ ジェネラル ホスピタル コーポレーション C型肝炎ウイルスのアンチセンス阻害
AU707811B2 (en) * 1995-05-05 1999-07-22 Australian Water Technologies Pty Ltd Method for the detection of viable Cryptosporidium parvum oocysts
AUPN283195A0 (en) * 1995-05-05 1995-06-01 Australian Water Technologies Pty Ltd Method for the detection of viable cryptosporidium parvum cells
IT1285158B1 (it) * 1996-09-17 1998-06-03 Angeletti P Ist Richerche Bio Polipeptidi solubili con l'attivita' di serino-proteasi di ns3 del virus dell'epatite c, e procedimento per la loro preparazione e il
AU4497999A (en) * 1998-04-28 1999-11-16 Ingrid-Corina Bergter Radioimmunopharmaca for treating hepatitis c

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GEP20002164B (en) * 1989-05-18 2000-07-10 Novartis Vaccines & Diagnostic Oligomers, method for detecting of hcv sequence, kit for its detecting, method for production of the blood free from hcv
CA2032907C (en) * 1989-12-22 2002-05-14 Richard R. Lesniewski Hepatitis c assay
KR940000755B1 (ko) * 1990-02-16 1994-01-29 유나이티드 바이오메디칼 인코오포레이티드 Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드
ZA912040B (en) * 1990-03-30 1991-12-24 Akzo Nv Peptides immunochemically reactive with antibodies directed against hepatitis non-a,non-b virus
EP0543924B1 (de) * 1990-08-10 1997-06-18 Chiron Corporation Nanbv diagnostik: für die untersuchung auf hepatitis c verwendbare polynukleotide
JP3114731B2 (ja) * 1990-08-14 2000-12-04 国立感染症研究所長 C型肝炎ウイルス抗体検出用ペプチド抗原及びその使用方法
EP0479376B1 (de) * 1990-10-05 1995-01-25 Akzo Nobel N.V. Mit Antikörper gegen Hepatitis-Virus non-A, non-B immunochemisch reagierende Peptide
EP0485209A1 (de) * 1990-11-08 1992-05-13 Immuno Japan Inc. Mit Non-A Non-B Hepatitis Virus verwandtes Antigen, Aufspürsysteme für Antikörper, Polynukleotide und Polypeptide
DE69030124T2 (de) * 1990-12-14 1997-09-18 Innogenetics Nv Synthetische Antigene zum Nachweis von Antikörpern gegen Hepatitis C-Virus

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9212992A2 *

Also Published As

Publication number Publication date
AU1459792A (en) 1992-08-27
WO1992012992A2 (en) 1992-08-06
WO1992012992A3 (en) 1993-03-18

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