EP0570452A1 - Improved surgical hardware with bacteriostatic silver coating, and method of using same - Google Patents

Improved surgical hardware with bacteriostatic silver coating, and method of using same

Info

Publication number
EP0570452A1
EP0570452A1 EP19920904466 EP92904466A EP0570452A1 EP 0570452 A1 EP0570452 A1 EP 0570452A1 EP 19920904466 EP19920904466 EP 19920904466 EP 92904466 A EP92904466 A EP 92904466A EP 0570452 A1 EP0570452 A1 EP 0570452A1
Authority
EP
European Patent Office
Prior art keywords
hardware
silver
surgical
silver coating
wound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19920904466
Other languages
German (de)
French (fr)
Inventor
Claude Vidal
Russell J. Redmond
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3M Co
Original Assignee
Minnesota Mining and Manufacturing Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minnesota Mining and Manufacturing Co filed Critical Minnesota Mining and Manufacturing Co
Publication of EP0570452A1 publication Critical patent/EP0570452A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/064—Surgical staples, i.e. penetrating the tissue

Definitions

  • This invention relates to surgical hardware of the type used to close wounds, and to an improved method of closing wounds using such hardware.
  • Various items of metal hardware have been developed to assist in closing wounds. At one time such hardware was made from solid silver. However, because of silver's high ductility and relatively low strength, silver hardware had to be made very coarse to have adequate mechanical properties. For many applications solid silver hardware was objectionably coarse. High strength metals such as stainless steel and titanium, permit more slender, clinically desirable hardware designs, and have for decades been the state of the art materials for surgical hardware.
  • Wound infection is always a serious concern because of its system-wide effect and retardation of normal wound healing, but when surgical hardware is required and used there are additional potential complications from wound infection including dehiscence or splitting of the wound, leakage from the wound, and formation of adhesions. While conventional steel and titanium hardware can be sterilized, it does not appear to have significant bacteriostatic effect, and may actually promote infection compared with other materials. Nevertheless, because these high strength metals permit the manufacture of such small, high strength hardware, these metals are still widely used.
  • the present invention provides an improved item of surgical hardware that provides the strength and compact size of a high strength metal such as stainless steel or titanium, and bacteriostatic properties to reduce the risk of wound infection.
  • This hardware allows wounds to be neatly and effectively closed, and provides some bacteriostatic action that reduces the risk of many of the complications encountered in the use of surgical hardware.
  • the invention relates to a staple, wire suture, clip, or other item of surgical hardware used in closing wounds.
  • the surgical hardware constructed according to the principles of the present invention comprises an item of surgical hardware that is made from a high strength metal, for example stainless steel or titanium, and which has a silver coating.
  • the silver coating may be either silver plating, or a coating of silver salt.
  • the method of closing wounds comprises closing the wounds with surgical hardware made from a high strength metal and which has a silver coating.
  • the hardware of the present invention provides all of the advantages of being constructed from a high strength metal, including high strength and compact size, and the additional benefit of bacteriostatic action which helps to reduce the risk of complications resulting from the use of the hardware.
  • the compact design permitted by the present invention ensures that the hardware has sufficient strength to hold the wound closed, and a sufficiently compact size that it does not unduly disturb the wound site or interfere with healing.
  • the cost of manufacturing hardware according to the principles of the present invention is only marginally higher than the cost of manufacturing conventional hardware.
  • the method of this invention provides a way to close wounds with reduced risk of infection and complications.
  • FIGURE 1 is a perspective view of an internal (soft tissue) staple constructed according to the principles of this invention
  • FIGURE 2 is a perspective view of a skin staple constructed according to the principles of this invention
  • FIGURE 3 is a perspective view of a fascia staple constructed according to the principles of this invention
  • FIGURE 4 is a. perspective view of a vascular staple constructed according to the principles of this invention
  • FIGURE 5 is a perspective view of a vascular clip constructed according to the principles of this invention
  • FIGURE 6 is a perspective view of a wire suture constructed according to the principles of this invention.
  • FIGURE 7 is a cross-sectional view of the wire suture, taken along the plane of line 7-7 in Figure 6.
  • Surgical staples constructed according to the principles of the present invention are indicated generally as 20, 22, 24, and 26 in Figures 1 - 4.
  • a surgical clip constructed according to the principles of the present invention is indicated generally as 28 in Figure 5.
  • a wire suture constructed according to the principles of the present invention is indicated generally as 30 in Figure 6.
  • the staples 20 - 26, the clip 28, and the suture 30 are made from a high strength surgical metal such as a stainless steel or titanium.
  • the staples 20 - 26, the clip 28, and the wire suture 30 have a silver coating. This is best shown in Figure 7 where the suture is shown as comprising high strength surgical metal 32 with a silver coating 34.
  • the silver coating provides a bacteriostatic action that inhibits infection. Thus infection is less likely to propagate when the surgical hardware of the present invention is used, and thus there is a reduced risk from infection-related complications from the use of such hardware.
  • the silver coating may be silver plating applied by a hot dip or electro-deposition process, or some other method.
  • the coating may be a silver salt applied to the exterior of the item of hardware, for example silver nitrate, or silver-zinc allantoinate.
  • the method of the present invention relates to an improved method of closing surgical wounds with reduced risk of infection.
  • the method comprises the step of closing the wound with a staple, wire suture, clip or other item of surgical hardware made from a high strength metal that has a silver coating.
  • the bacteriostatic effect of the hardware of this invention was tested by introducing a silver coated staple according to the principles of this invention, a stainless steel staple, and titanium staple into two difference agar media: Trypticase Soy Sheep Agar and Mueller Hinton Agar.
  • Each of the staples was screened against staph aureus, Escherichia coli, Pseudomonas aeriginosa, and strep faecales.
  • the plates were inoculated with a standard turbidity of a 0.5 McFarland standard.
  • the staples were placed on top of the agar and the plates were incubated at 35°C for 24 hours.
  • only the silver coated staple of the present invention showed any bacteriostatic action showing a zone of inhibition around the staple.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)

Abstract

L'invention se rapporte à une agrafe, un fil de suture, une attache ou autre article de matériel chirurgical, qui peut être utilisé pour fermer une plaie et qui est fabriqué à partir d'un métal très résistant de façon à présenter un profil extra-plat pour réduire au minimum les gênes occasionnées à la plaie, et qui possède un enrobage en argent bactériostatique destiné à réduire les risques d'infection de la plaie par le matériel. L'invention décrit également un procédé qui permet de fermer des plaies chirurgicales en réduisant les risques d'infection et qui consiste à fermer la plaie au moyen d'une agrafe, d'un fil de suture, d'une attache ou d'un autre article de matériel chirurgical fabriqué à partir d'un métal très résistant recouvert d'un enrobage d'argent.The invention relates to a staple, a suture, a tie or other article of surgical material, which can be used to close a wound and which is made from a very strong metal so as to have an extra profile. -flat to minimize discomfort caused to the wound, and which has a bacteriostatic silver coating intended to reduce the risk of infection of the wound by the material. The invention also describes a method of closing surgical wounds by reducing the risk of infection and comprising closing the wound with a staple, suture, tie, or another article of surgical material made from a very resistant metal covered with a silver coating.

Description

IMPROVED SURGICAL HARDWARE WITH BACTERIOSTATIC SILVER COATING. AND METHOD OF USING SAME
BACKGROUND OF THE INVENTION
This invention relates to surgical hardware of the type used to close wounds, and to an improved method of closing wounds using such hardware. Various items of metal hardware have been developed to assist in closing wounds. At one time such hardware was made from solid silver. However, because of silver's high ductility and relatively low strength, silver hardware had to be made very coarse to have adequate mechanical properties. For many applications solid silver hardware was objectionably coarse. High strength metals such as stainless steel and titanium, permit more slender, clinically desirable hardware designs, and have for decades been the state of the art materials for surgical hardware. Wound infection is always a serious concern because of its system-wide effect and retardation of normal wound healing, but when surgical hardware is required and used there are additional potential complications from wound infection including dehiscence or splitting of the wound, leakage from the wound, and formation of adhesions. While conventional steel and titanium hardware can be sterilized, it does not appear to have significant bacteriostatic effect, and may actually promote infection compared with other materials. Nevertheless, because these high strength metals permit the manufacture of such small, high strength hardware, these metals are still widely used.
SUMMARY OF THE INVENTION
The present invention provides an improved item of surgical hardware that provides the strength and compact size of a high strength metal such as stainless steel or titanium, and bacteriostatic properties to reduce the risk of wound infection. This hardware allows wounds to be neatly and effectively closed, and provides some bacteriostatic action that reduces the risk of many of the complications encountered in the use of surgical hardware. The invention relates to a staple, wire suture, clip, or other item of surgical hardware used in closing wounds. Generally, the surgical hardware constructed according to the principles of the present invention comprises an item of surgical hardware that is made from a high strength metal, for example stainless steel or titanium, and which has a silver coating. The silver coating may be either silver plating, or a coating of silver salt. Generally the method of closing wounds according to the present invention comprises closing the wounds with surgical hardware made from a high strength metal and which has a silver coating. The hardware of the present invention provides all of the advantages of being constructed from a high strength metal, including high strength and compact size, and the additional benefit of bacteriostatic action which helps to reduce the risk of complications resulting from the use of the hardware. The compact design permitted by the present invention ensures that the hardware has sufficient strength to hold the wound closed, and a sufficiently compact size that it does not unduly disturb the wound site or interfere with healing. The cost of manufacturing hardware according to the principles of the present invention is only marginally higher than the cost of manufacturing conventional hardware. The method of this invention provides a way to close wounds with reduced risk of infection and complications. These and other features and advantages will be in part apparent and in part pointed out hereinafter.
BRIEF DESCRIPTION OF THE DRAWINGS
FIGURE 1 is a perspective view of an internal (soft tissue) staple constructed according to the principles of this invention; FIGURE 2 is a perspective view of a skin staple constructed according to the principles of this invention; FIGURE 3 is a perspective view of a fascia staple constructed according to the principles of this invention; FIGURE 4 is a. perspective view of a vascular staple constructed according to the principles of this invention; FIGURE 5 is a perspective view of a vascular clip constructed according to the principles of this invention; FIGURE 6 is a perspective view of a wire suture constructed according to the principles of this invention; and
FIGURE 7 is a cross-sectional view of the wire suture, taken along the plane of line 7-7 in Figure 6.
Corresponding reference numerals indicate corresponding parts throughout the several views of the drawings.
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT
Surgical staples constructed according to the principles of the present invention are indicated generally as 20, 22, 24, and 26 in Figures 1 - 4. A surgical clip constructed according to the principles of the present invention is indicated generally as 28 in Figure 5. A wire suture constructed according to the principles of the present invention is indicated generally as 30 in Figure 6. Although the present invention is described with respect to staples, clips, and sutures, the invention is not so limited and relates to any item of surgical hardware of the type used to close wounds. The staples 20 - 26, the clip 28, and the suture 30 are made from a high strength surgical metal such as a stainless steel or titanium. Because they are constructed of a high strength material, these items have superior strength, and more importantly they can be designed to be small and compact so that they do not unnecessarily disturb the wound or interfere with proper healing. However, unlike any prior art item of surgical hardware, the staples 20 - 26, the clip 28, and the wire suture 30 have a silver coating. This is best shown in Figure 7 where the suture is shown as comprising high strength surgical metal 32 with a silver coating 34. The silver coating provides a bacteriostatic action that inhibits infection. Thus infection is less likely to propagate when the surgical hardware of the present invention is used, and thus there is a reduced risk from infection-related complications from the use of such hardware.
The silver coating may be silver plating applied by a hot dip or electro-deposition process, or some other method. Alternatively, the coating may be a silver salt applied to the exterior of the item of hardware, for example silver nitrate, or silver-zinc allantoinate.
The method of the present invention relates to an improved method of closing surgical wounds with reduced risk of infection. The method comprises the step of closing the wound with a staple, wire suture, clip or other item of surgical hardware made from a high strength metal that has a silver coating.
The bacteriostatic effect of the hardware of this invention was tested by introducing a silver coated staple according to the principles of this invention, a stainless steel staple, and titanium staple into two difference agar media: Trypticase Soy Sheep Agar and Mueller Hinton Agar. Each of the staples was screened against staph aureus, Escherichia coli, Pseudomonas aeriginosa, and strep faecales. The plates were inoculated with a standard turbidity of a 0.5 McFarland standard. The staples were placed on top of the agar and the plates were incubated at 35°C for 24 hours. As illustrated in the following table, only the silver coated staple of the present invention showed any bacteriostatic action showing a zone of inhibition around the staple.
Escherichia Pseudomonas Strep Staphaureus Coli Aeriginosa Faecales
In view of the above, it will be seen that the several objects of the invention are achieved and other advantageous results attained. As various changes could be made in the above constructions without departing from the scope of the invention, it is intended that all matter contained in the above description or shown in the accompanying drawings shall be interpreted as illustrative and not in a limited sense.

Claims

WHAT IS CLAIMED IS:
1. An improved staple, wire suture, clip, or other metallic item of surgical hardware of the type made from a high strength metal such as stainless steel or titanium, the improvement comprising a silver coating on the surface of the hardware.
2. The hardware according to claim I wherein the silver coating comprises silver plating.
3. The hardware according to claim 1 wherein the silver coating comprises silver salts.
4. A staple, wire suture, clip, or other item of surgical hardware used to close a wound, made from a high strength metal to have a low profile design to minimize interference and disturbance of the wound, and having a bacteriostatic silver coating to reduce the risk of wound infection from the hardware.
5. The hardware according to claim 4 wherein the silver coating comprises silver plating.
6. The hardware according to claim 4 wherein the silver coating comprises silver salts.
7. A method of closing surgical wounds with reduced risk of infection comprising the step of closing the wound with a staple, wire suture, clip or other item of surgical hardware made from a high strength metal that has a silver coating.
8. The method according to claim 4 wherein the silver coating comprises silver plating.
9. The method according to claim 4 wherein the silver coating comprises silver salts.
10. A surgical staple having bacteriostatic coating.
11. A surgical staple according to claim 1 wherein said bacteriostatic coating is silver.
EP19920904466 1991-02-06 1992-01-08 Improved surgical hardware with bacteriostatic silver coating, and method of using same Withdrawn EP0570452A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65335391A 1991-02-06 1991-02-06
US653353 1991-02-06

Publications (1)

Publication Number Publication Date
EP0570452A1 true EP0570452A1 (en) 1993-11-24

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
EP19920904466 Withdrawn EP0570452A1 (en) 1991-02-06 1992-01-08 Improved surgical hardware with bacteriostatic silver coating, and method of using same

Country Status (2)

Country Link
EP (1) EP0570452A1 (en)
WO (1) WO1992013491A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6861570B1 (en) 1997-09-22 2005-03-01 A. Bart Flick Multilayer conductive appliance having wound healing and analgesic properties
US6719987B2 (en) 2000-04-17 2004-04-13 Nucryst Pharmaceuticals Corp. Antimicrobial bioabsorbable materials
KR20020057446A (en) * 2001-01-04 2002-07-11 안정오 Operating Room with Gold or Silver
ES2261659T3 (en) 2001-04-23 2006-11-16 Nucryst Pharmaceuticals Corp. A MEDICINAL OR PREPARATION CONTAINING A METAL SUCH AS SILVER, GOLD, PLATINUM OR PALADIO AS AN ANTIMICROBIAL AGENT AND ITS USE FOR THE TREATMENT OF INFLAMMATORY STATES OF THE SKIN.
EP1465673B1 (en) 2001-12-20 2007-01-24 Noble Fiber Technologies, LLC Wound dressings comprising metallic silver
US6921546B2 (en) 2003-02-20 2005-07-26 Gemtron Corporation Antimicrobial glass and glass-like products and method of preparing same
ES2279231T3 (en) 2003-05-09 2007-08-16 Tyco Healthcare Group Lp ANASTOMOTIC STAPLE WITH CAPILLARY TUBE THAT DISPENSES FLUIDS.
CN2734238Y (en) * 2004-08-25 2005-10-19 任晓艳 Nano silver coated suture line
ES2748926T3 (en) 2004-10-18 2020-03-18 Covidien Lp Surgical fixings coated with wound treatment materials
EP2662051A1 (en) * 2012-05-11 2013-11-13 Dentsply IH AB Medical device having a surface comprising nanoparticles
RU2517121C2 (en) * 2012-08-21 2014-05-27 Государственное научное учреждение Институт экспериментальной ветеринарии Сибири и Дальнего Востока Российской академии сельскохозяйственных наук (ГНУ ИЭВСиДВ Россельхозакадемии) Method for improving quality of surgical suture
WO2023009082A1 (en) * 2021-07-30 2023-02-02 Dogan Oezcan Surgical skin staples with silver ion coating
RU2770277C1 (en) * 2021-08-23 2022-04-15 Федеральное государственное бюджетное учреждение науки Южный научный центр Российской академии наук (ЮНЦ РАН) Method for increasing the quantity and antibacterial activity of silver nanoparticles on a silk suture material

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DE3164658D1 (en) * 1980-03-27 1984-08-16 Nat Res Dev Orthopaedic implants
CA1170536A (en) * 1980-08-25 1984-07-10 United States Surgical Corporation Surgical staples
CH654738A5 (en) * 1985-02-26 1986-03-14 Ines Blaettler Surgical implants and repair plates
US4886505A (en) * 1985-06-07 1989-12-12 Becton, Dickinson And Company Antimicrobial surfaces and inhibition of microorganism growth thereby
US4728323A (en) * 1986-07-24 1988-03-01 Minnesota Mining And Manufacturing Company Antimicrobial wound dressings
US5019096A (en) * 1988-02-11 1991-05-28 Trustees Of Columbia University In The City Of New York Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same
GR1000814B (en) * 1989-06-30 1993-01-25 Ethicon Inc Image enhancing surgical staple

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Also Published As

Publication number Publication date
WO1992013491A1 (en) 1992-08-20

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