EP0548376A4 - - Google Patents
Info
- Publication number
- EP0548376A4 EP0548376A4 EP19920915918 EP92915918A EP0548376A4 EP 0548376 A4 EP0548376 A4 EP 0548376A4 EP 19920915918 EP19920915918 EP 19920915918 EP 92915918 A EP92915918 A EP 92915918A EP 0548376 A4 EP0548376 A4 EP 0548376A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- heparin
- cytokine
- administering
- active ingredients
- drug containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 108090000695 Cytokines Proteins 0.000 abstract 2
- 102000004127 Cytokines Human genes 0.000 abstract 2
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 2
- 108010002352 Interleukin-1 Proteins 0.000 abstract 2
- 108010002350 Interleukin-2 Proteins 0.000 abstract 2
- 229960002897 heparin Drugs 0.000 abstract 2
- 229920000669 heparin Polymers 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 229940041181 antineoplastic drug Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2006—IL-1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2013—IL-2
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17973991 | 1991-07-19 | ||
| JP179739/91 | 1991-07-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP0548376A1 EP0548376A1 (en) | 1993-06-30 |
| EP0548376A4 true EP0548376A4 (OSRAM) | 1994-02-02 |
Family
ID=16071023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP92915918A Withdrawn EP0548376A1 (en) | 1991-07-19 | 1992-07-16 | Antitumor drug |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP0548376A1 (OSRAM) |
| WO (1) | WO1993001825A1 (OSRAM) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10682626B2 (en) | 2013-03-14 | 2020-06-16 | Zeomem Sweden Ab | Method for producing a crystalline film of zeolite and/or zeolite like crystals on a porous substrate |
| GB201714269D0 (en) | 2017-09-05 | 2017-10-18 | Hedlund Jonas | Methods for preparing supported zeolite films |
| WO2021041532A1 (en) * | 2019-08-26 | 2021-03-04 | Dana-Farber Cancer Institute, Inc. | Use of heparin to promote type 1 interferon signaling |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02157231A (ja) * | 1988-12-07 | 1990-06-18 | Bio Kagaku Kenkyusho:Kk | 細胞増殖抑制剤 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5892620A (ja) * | 1981-11-28 | 1983-06-02 | Sunstar Inc | インタ−フエロン安定配合組成物 |
| JPS59176213A (ja) * | 1982-12-20 | 1984-10-05 | プレジデント アンド フエロ−ズ オブ ハ−バ−ド カリツジ | 脈管形成抑制剤 |
| JP3022566B2 (ja) * | 1987-10-02 | 2000-03-21 | ザ ロックフェラー ユニバーシティ | 大食細胞誘導炎症性神経細胞 |
| JPH02213A (ja) * | 1987-10-19 | 1990-01-05 | Taiho Yakuhin Kogyo Kk | 生理活性ペプチド持続製剤 |
| DE3808353A1 (de) * | 1988-03-12 | 1989-09-21 | Basf Ag | Kombinationen von polysulfatierten heparinen bei der bekaempfung von retrovirusinfektionen |
| JPH0240399A (ja) * | 1988-07-27 | 1990-02-09 | Takeda Chem Ind Ltd | 線維芽細胞増殖因子ムテインの複合体あるいは組成物 |
| JPH02111726A (ja) * | 1988-10-19 | 1990-04-24 | Dainippon Pharmaceut Co Ltd | ヒト インターロイキン1を安定化する方法 |
| JPH03127740A (ja) * | 1989-10-11 | 1991-05-30 | Teijin Ltd | 悪性腫瘍治療剤 |
-
1992
- 1992-07-16 WO PCT/JP1992/000905 patent/WO1993001825A1/ja not_active Ceased
- 1992-07-16 EP EP92915918A patent/EP0548376A1/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02157231A (ja) * | 1988-12-07 | 1990-06-18 | Bio Kagaku Kenkyusho:Kk | 細胞増殖抑制剤 |
Non-Patent Citations (4)
| Title |
|---|
| DATABASE WPI Section Ch Week 9030, Derwent World Patents Index; Class B04, AN 90-228676 * |
| R. DZIARSKI: "Enhancement of mixed leukocyte reaction and cytotoxic antitumor responses by heparin.", J. IMMUNOL., vol. 143, no. 1, 1989, pages 356 - 365 * |
| R. DZIARSKI: "Synergistic enhancement of T cell responses and Interleukin-1 receptor expression by Interleukin-1 and heparin or dextran sulfate.", CELL. IMMUNOL., vol. 145, no. 1, November 1992 (1992-11-01), pages 100 - 110 * |
| See also references of WO9301825A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0548376A1 (en) | 1993-06-30 |
| WO1993001825A1 (fr) | 1993-02-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 19930311 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): DE FR GB IT MC |
|
| RBV | Designated contracting states (corrected) |
Designated state(s): DE FR GB IT |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 19931216 |
|
| AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): DE FR GB IT MC |
|
| 17Q | First examination report despatched |
Effective date: 19951228 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 19971108 |