EP0548245A4 - - Google Patents

Info

Publication number
EP0548245A4
EP0548245A4 EP19910917284 EP91917284A EP0548245A4 EP 0548245 A4 EP0548245 A4 EP 0548245A4 EP 19910917284 EP19910917284 EP 19910917284 EP 91917284 A EP91917284 A EP 91917284A EP 0548245 A4 EP0548245 A4 EP 0548245A4
Authority
EP
European Patent Office
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19910917284
Other versions
EP0548245A1 (en
Inventor
Alfons M. Verbruggen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Inc
Original Assignee
Mallinckrodt Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Medical Inc filed Critical Mallinckrodt Medical Inc
Publication of EP0548245A1 publication Critical patent/EP0548245A1/en
Publication of EP0548245A4 publication Critical patent/EP0548245A4/xx
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0476—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP91917284A 1990-06-18 1991-06-14 Metal-radionuclide complex comprising isonitrile ligands Withdrawn EP0548245A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP90201569 1990-06-18
EP90201569 1990-06-18

Publications (2)

Publication Number Publication Date
EP0548245A1 EP0548245A1 (en) 1993-06-30
EP0548245A4 true EP0548245A4 (Direct) 1994-01-26

Family

ID=8205034

Family Applications (1)

Application Number Title Priority Date Filing Date
EP91917284A Withdrawn EP0548245A1 (en) 1990-06-18 1991-06-14 Metal-radionuclide complex comprising isonitrile ligands

Country Status (5)

Country Link
EP (1) EP0548245A1 (Direct)
JP (1) JPH05508162A (Direct)
AU (1) AU8542591A (Direct)
CA (1) CA2085364A1 (Direct)
WO (1) WO1991019516A1 (Direct)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2679452B1 (fr) * 1991-07-22 1993-11-12 Cis Bio International Produit radiopharmaceutique ayant notamment un tropisme cerebral, comportant un complexe nitruro d'un metal de transition, et son procede de preparation.
EP1286704B1 (en) * 2000-06-02 2014-07-23 Board of Regents, The University of Texas System ETHYLENEDICYSTEINE (EC)-glucose analog CONJUGATES
US10925977B2 (en) 2006-10-05 2021-02-23 Ceil>Point, LLC Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1305160C (en) * 1985-12-23 1992-07-14 Paul Louis Bergstein Ether isonitriles and radiolabeled complexes thereof
US4885100A (en) * 1987-09-11 1989-12-05 E. I. Du Pont De Nemours And Company Tris(isonitrile)copper(I) adducts for preparing radionuclide complexes

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO9119516A1 *
T. R. CARROLL ET AL: "SYNTHESIS AND PHARMACOKINETICS OF A NEW SERIES OF TECHNETIUM-99M ISONITRILE COMPLEXES", JOURNAL OF NUCLEAR MEDICINE., vol. 29, no. 5, May 1988 (1988-05-01), NEW YORK US, pages 934 *

Also Published As

Publication number Publication date
WO1991019516A1 (en) 1991-12-26
CA2085364A1 (en) 1991-12-19
EP0548245A1 (en) 1993-06-30
JPH05508162A (ja) 1993-11-18
AU8542591A (en) 1992-01-07

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19921211

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU NL SE

A4 Supplementary search report drawn up and despatched

Effective date: 19931207

AK Designated contracting states

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Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU NL SE

17Q First examination report despatched

Effective date: 19940413

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19940824