EP0538267A4 - Monoclonal anti-igm antibodies, their production and use, and hybridomas for producing the same - Google Patents

Monoclonal anti-igm antibodies, their production and use, and hybridomas for producing the same

Info

Publication number
EP0538267A4
EP0538267A4 EP19910909436 EP91909436A EP0538267A4 EP 0538267 A4 EP0538267 A4 EP 0538267A4 EP 19910909436 EP19910909436 EP 19910909436 EP 91909436 A EP91909436 A EP 91909436A EP 0538267 A4 EP0538267 A4 EP 0538267A4
Authority
EP
European Patent Office
Prior art keywords
hybridomas
producing
production
same
monoclonal anti
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19910909436
Other languages
English (en)
Other versions
EP0538267A1 (en
Inventor
Michael G Rosenblum
Nicholas J Donato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Development Foundation
Original Assignee
Research Development Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Development Foundation filed Critical Research Development Foundation
Publication of EP0538267A1 publication Critical patent/EP0538267A1/en
Publication of EP0538267A4 publication Critical patent/EP0538267A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6873—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting an immunoglobulin; the antibody being an anti-idiotypic antibody
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP19910909436 1990-04-27 1991-04-24 Monoclonal anti-igm antibodies, their production and use, and hybridomas for producing the same Withdrawn EP0538267A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51597490A 1990-04-27 1990-04-27
US515974 1990-04-27

Publications (2)

Publication Number Publication Date
EP0538267A1 EP0538267A1 (en) 1993-04-28
EP0538267A4 true EP0538267A4 (en) 1994-06-01

Family

ID=24053580

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19910909436 Withdrawn EP0538267A4 (en) 1990-04-27 1991-04-24 Monoclonal anti-igm antibodies, their production and use, and hybridomas for producing the same

Country Status (12)

Country Link
EP (1) EP0538267A4 (ru)
JP (1) JPH06504424A (ru)
CN (1) CN1057072A (ru)
CA (1) CA2079901A1 (ru)
IE (1) IE911172A1 (ru)
IL (1) IL97827A0 (ru)
NZ (1) NZ237784A (ru)
PT (1) PT97482B (ru)
RU (1) RU2105062C1 (ru)
TW (1) TW349995B (ru)
WO (1) WO1991017257A1 (ru)
ZA (1) ZA912695B (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2322562B1 (en) 2008-09-05 2016-03-30 Sekisui Medical Co., Ltd. Monoclonal antibody, and immunoassay using same
CN108384761B (zh) * 2018-03-30 2020-08-11 四川迈克生物新材料技术有限公司 抗人IgM单克隆抗体、其杂交瘤细胞株及应用
WO2023088443A1 (zh) * 2021-11-20 2023-05-25 东莞市朋志生物科技有限公司 一种抗人IgM抗体及其制备方法和用途

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4792447A (en) * 1981-07-23 1988-12-20 Board Of Regents, The University Of Texas System Anti-immunoglobulin toxin conjugates useful in the treatment of B cell tumors
WO1992007574A1 (en) * 1990-10-25 1992-05-14 Tanox Biosystems, Inc. Glycoproteins associated with membrane-bound immunoglobulins as antibody targets on b cells

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4792447A (en) * 1981-07-23 1988-12-20 Board Of Regents, The University Of Texas System Anti-immunoglobulin toxin conjugates useful in the treatment of B cell tumors
WO1992007574A1 (en) * 1990-10-25 1992-05-14 Tanox Biosystems, Inc. Glycoproteins associated with membrane-bound immunoglobulins as antibody targets on b cells

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
ARMTIAGE RJ. ET AL.: "FUNCTIONAL INTERACTION BETWEEN B CELL SUBPOPULATIONS DEFINED BY CD23 EXPRESSION", EUR. J. IMMUNOL., vol. 18, no. 11, November 1988 (1988-11-01), pages 1753 - 1760 *
CHARLES L. SIDMAN ET AL.: "PROLIFERATIVE RESPONSE TO ANTI-IGM AN", JOURNAL OF IMMUNOLOGY, vol. 121, no. 6, December 1978 (1978-12-01), BALTIMORE US, pages 2129 - 2136 *
CHEMICAL ABSTRACTS, vol. 103, no. 17, 28 October 1985, Columbus, Ohio, US; abstract no. 134580t *
DATABASE MEDLINE US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; *
See also references of WO9117257A1 *
TIMOTHY A. SPRINGER ET AL.: "MOAB'S SPECIFIC FOR RAT IGG1, IGG2, AND IGG2B SUBCLASSES, AND KAPPA CHAIN MONOTYPIC AND ALLOTYPIC DETERMINANTS: REAGENTS FOR USE WITH RAT MOAB'S.", HYBRIDOMA, vol. 1, no. 3, 1982, pages 257 - 273 *
UMEMOTO NAOJI ET AL.: "CONJUGATES OF MITOMYCIN C WITH TH IMMUNOGLOBULIN M MONOMER FRAGMENT OF A MONOCLONAL ANTI-mm46 IMMUNOGLOBULIN M ANTIBODY WITH OR WITHOUT SERUM ALBUMIN AS INTERMEDIARY.", J. APPL. BIOCHEM., vol. 6, no. 5, 1984, pages 297 - 307, XP008123489 *

Also Published As

Publication number Publication date
CA2079901A1 (en) 1991-10-28
NZ237784A (en) 1992-09-25
TW349995B (en) 1999-01-11
EP0538267A1 (en) 1993-04-28
ZA912695B (en) 1993-02-24
PT97482A (pt) 1992-01-31
PT97482B (pt) 1998-08-31
IE911172A1 (en) 1991-11-06
AU7866491A (en) 1991-11-27
IL97827A0 (en) 1992-06-21
AU650659B2 (en) 1994-06-30
CN1057072A (zh) 1991-12-18
RU2105062C1 (ru) 1998-02-20
WO1991017257A1 (en) 1991-11-14
JPH06504424A (ja) 1994-05-26

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