EP0452360A4 - Methods and compositions for the prophylaxis and treatment of hepatitis b virus infections - Google Patents

Methods and compositions for the prophylaxis and treatment of hepatitis b virus infections

Info

Publication number
EP0452360A4
EP0452360A4 EP19900901415 EP90901415A EP0452360A4 EP 0452360 A4 EP0452360 A4 EP 0452360A4 EP 19900901415 EP19900901415 EP 19900901415 EP 90901415 A EP90901415 A EP 90901415A EP 0452360 A4 EP0452360 A4 EP 0452360A4
Authority
EP
European Patent Office
Prior art keywords
prophylaxis
hepatitis
compositions
treatment
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19900901415
Other versions
EP0452360A1 (en
Inventor
Peter M. Palese
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP0452360A1 publication Critical patent/EP0452360A1/en
Publication of EP0452360A4 publication Critical patent/EP0452360A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP19900901415 1988-12-12 1989-12-11 Methods and compositions for the prophylaxis and treatment of hepatitis b virus infections Withdrawn EP0452360A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28330388A 1988-12-12 1988-12-12
US283303 1988-12-12

Publications (2)

Publication Number Publication Date
EP0452360A1 EP0452360A1 (en) 1991-10-23
EP0452360A4 true EP0452360A4 (en) 1992-05-20

Family

ID=23085400

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19900901415 Withdrawn EP0452360A4 (en) 1988-12-12 1989-12-11 Methods and compositions for the prophylaxis and treatment of hepatitis b virus infections

Country Status (5)

Country Link
EP (1) EP0452360A4 (en)
KR (1) KR910700054A (en)
AU (1) AU4829190A (en)
CA (1) CA2005192A1 (en)
WO (1) WO1990006671A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD293498A5 (en) * 1989-07-20 1991-09-05 Zi Fuer Molekularbiologie Der Adw,De METHOD FOR PRODUCING A MEDIUM FOR THE TREATMENT OR PROPHYLAXIS OF HEPATITE INFECTIONS IN HUMANS AND ANIMALS
JPH05506211A (en) * 1990-02-09 1993-09-16 アメリカ合衆国 6-halo- and 2-amino-6-halo-purines 2',3'-dideoxynucleosides and their use as antiviral agents
GB9204015D0 (en) * 1992-02-25 1992-04-08 Wellcome Found Therapeutic nucleosides
TWI229674B (en) 1998-12-04 2005-03-21 Astra Pharma Prod Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses
WO2018181102A1 (en) * 2017-03-29 2018-10-04 ヤマサ醤油株式会社 Nucleoside derivative or salt thereof, and pharmaceutical composition containing same

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0236935A2 (en) * 1986-03-06 1987-09-16 Takeda Chemical Industries, Ltd. Carboxylic purine nucleosides, their production and use
US4728736A (en) * 1984-03-28 1988-03-01 Southern Research Institute Carbocyclic analogs of purine ribofuranosides
EP0349242A2 (en) * 1988-06-27 1990-01-03 The Wellcome Foundation Limited Therapeutic nucleosides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4728736A (en) * 1984-03-28 1988-03-01 Southern Research Institute Carbocyclic analogs of purine ribofuranosides
EP0236935A2 (en) * 1986-03-06 1987-09-16 Takeda Chemical Industries, Ltd. Carboxylic purine nucleosides, their production and use
EP0349242A2 (en) * 1988-06-27 1990-01-03 The Wellcome Foundation Limited Therapeutic nucleosides

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
J. MED. CHEM., vol. 27, no. 11, 1984, pages 1416-1421, American Chemical Society; Y. F. SHEALY et al.: "Synthesis and antiviral activity of carbocyclic analogues of 2'-deoxyribofuranosides of 2-amino-6-substituted-purines and of 2-amino-6-substituted-8-azapurines" *
J. MED. CHEM., vol. 27, no. 5, 1984, pages 670-674, American Chemical Society; Y. F. SHEALY et al.: "Synthesis and antiviral evaluation of carbocyclic analogues of ribofuranosides of 2-amino-6-substituted-purines and of 2-amino-6-substituted-8-azapurines" *
PROC. NATL. ACAD. SCI. USA, vol. 86, no. 21, November 1989, pages 8541-8544; P. M. PRICE et al.: "Inhibition of the replication of hepatitis B virus by the carbocyclic analogue of 2'-deoxyguanosine" *

Also Published As

Publication number Publication date
WO1990006671A2 (en) 1990-06-28
KR910700054A (en) 1991-03-13
AU4829190A (en) 1990-07-10
CA2005192A1 (en) 1990-06-12
EP0452360A1 (en) 1991-10-23

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19910611

AK Designated contracting states

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A4 Supplementary search report drawn up and despatched

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18D Application deemed to be withdrawn

Effective date: 19941018