EP0429585A4 - Cytochalasin compositions and therapeutic methods - Google Patents
Cytochalasin compositions and therapeutic methodsInfo
- Publication number
- EP0429585A4 EP0429585A4 EP19900907829 EP90907829A EP0429585A4 EP 0429585 A4 EP0429585 A4 EP 0429585A4 EP 19900907829 EP19900907829 EP 19900907829 EP 90907829 A EP90907829 A EP 90907829A EP 0429585 A4 EP0429585 A4 EP 0429585A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- cytochalasin
- compositions
- therapeutic methods
- therapeutic
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/4035—Isoindoles, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34501089A | 1989-04-28 | 1989-04-28 | |
US345010 | 1989-04-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0429585A1 EP0429585A1 (fr) | 1991-06-05 |
EP0429585A4 true EP0429585A4 (en) | 1992-03-25 |
Family
ID=23353087
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19900907829 Withdrawn EP0429585A4 (en) | 1989-04-28 | 1990-04-27 | Cytochalasin compositions and therapeutic methods |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0429585A4 (fr) |
JP (1) | JPH03505744A (fr) |
CA (1) | CA2031520A1 (fr) |
WO (1) | WO1990013293A1 (fr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5250563A (en) * | 1991-09-25 | 1993-10-05 | Merck & Co., Inc. | Inhibitors of HIV protease |
US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5811447A (en) * | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
EP0616530A1 (fr) * | 1991-12-09 | 1994-09-28 | Usher, Thomas Clemens | Utilisation de cytochalasines pour inhiber la replication virale |
US5981568A (en) | 1993-01-28 | 1999-11-09 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5342926A (en) * | 1993-06-08 | 1994-08-30 | The Regents Of The University Of California | Analogs of cytochalasin B as radiopharmaceuticals for nuclear imaging of trans-membrane glucose transport |
EP1512398A1 (fr) | 1997-03-31 | 2005-03-09 | Boston Scientific Limited | Stent intravasculaire avec des inhibiteurs cytosquelettiques pour la prévention de la restenose |
US6787132B1 (en) * | 1997-12-04 | 2004-09-07 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Combined chemo-immunotherapy with liposomal drugs and cytokines |
ATE442128T1 (de) * | 1997-12-04 | 2009-09-15 | Yissum Res Dev Co | Kombinierte chemo-immunotherapie mit liposomalen arzneistoffen und cytokinen |
DE10115740A1 (de) | 2001-03-26 | 2002-10-02 | Ulrich Speck | Zubereitung für die Restenoseprophylaxe |
DE10244847A1 (de) | 2002-09-20 | 2004-04-01 | Ulrich Prof. Dr. Speck | Medizinische Vorrichtung zur Arzneimittelabgabe |
JP5397692B2 (ja) * | 2007-11-28 | 2014-01-22 | 国立大学法人名古屋大学 | 悪性黒色腫抗原の発現上昇剤及びその用途 |
US11007176B2 (en) | 2019-02-19 | 2021-05-18 | Tzu Chi University | Use of actin depolymerizing agents for the treatment of anxiety disorders |
CN110563634B (zh) * | 2019-09-09 | 2020-12-08 | 湖南省中医药研究院 | 吲哚细胞松弛素类化合物及其制备方法和应用 |
CN111249445B (zh) * | 2020-02-27 | 2022-11-15 | 广东医科大学 | 一种细胞松弛素h软胶囊及其制备方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0291151A1 (fr) * | 1984-08-13 | 1988-11-17 | Harry H. Leveen | Compositions contenant des dérivés de phlorizine pour le traitement du cancer |
EP0297946A2 (fr) * | 1987-06-19 | 1989-01-04 | Syracuse University | Méthodes de purification de cytochalasine et ses compositions |
-
1990
- 1990-04-27 JP JP2507126A patent/JPH03505744A/ja active Pending
- 1990-04-27 EP EP19900907829 patent/EP0429585A4/en not_active Withdrawn
- 1990-04-27 CA CA002031520A patent/CA2031520A1/fr not_active Abandoned
- 1990-04-27 WO PCT/US1990/002342 patent/WO1990013293A1/fr not_active Application Discontinuation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0291151A1 (fr) * | 1984-08-13 | 1988-11-17 | Harry H. Leveen | Compositions contenant des dérivés de phlorizine pour le traitement du cancer |
EP0297946A2 (fr) * | 1987-06-19 | 1989-01-04 | Syracuse University | Méthodes de purification de cytochalasine et ses compositions |
Non-Patent Citations (3)
Title |
---|
CANCER IMMUNOLOGY IMMUNOTHERAPY, vol. 32, no. 6, 1991, pages 400-405, Springer Verlag; D. BOGYO et al.: "Cytochalasin-B-induced immunosuppression of murine allogeneic anti-tumor response and the effect of recombinant human interleukin-2" * |
CELLULAR IMMUNOLOGY, vol. 69, 1982, pages 235-247, Academic Press, Inc.; S. STOSIC-GRUJICIC et al.: "Modulation of interleukin 1 production by activated macrophages: in vitro action of hydrocortisone, colchicine and cytochalasin B1" * |
See also references of WO9013293A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO1990013293A1 (fr) | 1990-11-15 |
JPH03505744A (ja) | 1991-12-12 |
EP0429585A1 (fr) | 1991-06-05 |
CA2031520A1 (fr) | 1990-10-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB IT LI LU NL SE |
|
17P | Request for examination filed |
Effective date: 19910506 |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19920206 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB IT LI LU NL SE |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 19920422 |