EP0429522A1 - Phosphosugar-based anti-inflammatory and/or immunosuppressive drugs. - Google Patents
Phosphosugar-based anti-inflammatory and/or immunosuppressive drugs.Info
- Publication number
- EP0429522A1 EP0429522A1 EP89909685A EP89909685A EP0429522A1 EP 0429522 A1 EP0429522 A1 EP 0429522A1 EP 89909685 A EP89909685 A EP 89909685A EP 89909685 A EP89909685 A EP 89909685A EP 0429522 A1 EP0429522 A1 EP 0429522A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- phosphosugar
- phosphate
- mannose
- polysaccharide
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
- C07H11/04—Phosphates; Phosphites; Polyphosphates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Description
Claims
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU9942/88 | 1988-08-19 | ||
AUPI994288 | 1988-08-19 | ||
PCT/AU1989/000350 WO1990001938A1 (en) | 1988-08-19 | 1989-08-18 | Phosphosugar-based anti-inflammatory and/or immunosuppressive drugs |
Publications (3)
Publication Number | Publication Date |
---|---|
EP0429522A1 true EP0429522A1 (en) | 1991-06-05 |
EP0429522A4 EP0429522A4 (en) | 1991-09-11 |
EP0429522B1 EP0429522B1 (en) | 1996-06-26 |
Family
ID=3773299
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP89909685A Expired - Lifetime EP0429522B1 (en) | 1988-08-19 | 1989-08-18 | Phosphosugar-based anti-inflammatory and/or immunosuppressive drugs |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0429522B1 (en) |
AT (1) | ATE139699T1 (en) |
DE (1) | DE68926746T2 (en) |
WO (1) | WO1990001938A1 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5308838A (en) * | 1982-05-07 | 1994-05-03 | Carrington Laboratories, Inc. | Uses of aloe products |
US5646123A (en) * | 1991-06-10 | 1997-07-08 | Alberta Research Council | Time dependent administration of oligosaccharide glycosides related to blood group determinants having a type I or type II core structure in reducing inflammation in a sensitized mammal arising form exposure to an antigen |
GB2299025B (en) * | 1992-03-17 | 1996-11-27 | British Tech Group | Dispenser containing a formulation of mannose phosphate useful in the treatment of fibrotic disorders of the eye |
GB9205800D0 (en) * | 1992-03-17 | 1992-04-29 | British Tech Group | Treatment of fibrotic disorders |
US5747461A (en) * | 1994-07-26 | 1998-05-05 | Markov; Angel K. | Synergistic administration of cyclosporine and fructose diphosphate |
SE9403137D0 (en) | 1994-09-20 | 1994-09-20 | Perstorp Ab | Derivatives of carbohydrates and compositions containing them |
GB9516012D0 (en) * | 1995-08-04 | 1995-10-04 | Univ Manchester | Pharmaceutical composition |
US6566339B1 (en) | 1995-08-04 | 2003-05-20 | Renovo Limited | Pharmaceutical composition |
US6093388A (en) * | 1996-08-12 | 2000-07-25 | Btg International Limited | Mannose-6-phosphate composition and its use in treating fibrotic disorders |
AUPO309896A0 (en) | 1996-10-18 | 1996-11-14 | Australian National University, The | Novel phosphosugars and phosphosugar-containing compounds having anti-inflammatory activity |
CA2548219A1 (en) | 2003-12-18 | 2005-06-30 | Yehudit Amor | Method for analyzing a glycomolecule |
US7276486B2 (en) * | 2004-03-15 | 2007-10-02 | Kimberly-Clark Worldwide, Inc. | Compositions for vaginal treatment |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58121216A (en) * | 1982-01-13 | 1983-07-19 | Grelan Pharmaceut Co Ltd | Phosphorus-containing mannan |
JPS63119427A (en) * | 1986-11-05 | 1988-05-24 | Kao Corp | Antiallergic agent |
US4761402A (en) * | 1985-08-19 | 1988-08-02 | Bioglucans, L.P. | Methods and compositions for prophylactic and therapeutic treatment of infections |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE334250C (en) * | 1918-05-11 | 1921-03-14 | Farbenfab Vorm Bayer F & Co | Process for the preparation of fructose monophosphoric acid |
US4122179A (en) * | 1976-06-03 | 1978-10-24 | Enrico Corvi Mora | Acid addition salts of vincamine and apovincamine |
IT1143956B (en) * | 1980-03-12 | 1986-10-29 | Foscama Biomed Chim Farma | FRUCTOSE-1,6-DIPHOSPHATE PREPARATION WITH PROTECTIVE ACTION OF THE ERYTHROCYTE MEMBRANE IN PATIENTS SUBJECT TO EXTRACORPOREA CIRCULATION |
IT1164363B (en) * | 1983-08-03 | 1987-04-08 | Foscama Biomed Chim Farma | THERAPEUTIC PROCEDURE FOR THE USE OF EMBORNED LIPOSOMES FRUCTOSE 1.6 DIPHOSPHATE AND PROCEDURE FOR THE PREPARATION OF THE SAME |
IT1209519B (en) * | 1984-04-10 | 1989-08-30 | Poli Ind Chimica Spa | CARDIOTROPHIC ACTIVITY COMPOUNDS. |
ES8602951A1 (en) * | 1985-03-15 | 1985-12-16 | Vinas Lab | New derivative of fructose, its preparation and its uses. |
US4703040A (en) * | 1985-04-03 | 1987-10-27 | Markov Angel K | Treatment of adult respiratory distress syndrome (ARDS) using fructose diphosphate (FDP) |
NL8601551A (en) * | 1985-06-28 | 1987-01-16 | Sandoz Ag | NEW SACCHARIDES, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
DE3731953A1 (en) * | 1987-09-23 | 1989-04-06 | Sandoz Ag | NEW SACCHARID, METHOD FOR THEIR PRODUCTION AND THEIR USE |
IT1204764B (en) * | 1986-01-17 | 1989-03-10 | Foscama Biomed Chim Farma | THERAPEUTIC USE OF FRUCTOSE-1,6-DIPHOSPHATE FOR THE PROTECTION AGAINST TOXICITY INDUCED BY THE ADMINISTRATION OF ANTHRACYCLINIC ANTI-TUMORAL AGENTS |
-
1989
- 1989-08-18 AT AT89909685T patent/ATE139699T1/en not_active IP Right Cessation
- 1989-08-18 EP EP89909685A patent/EP0429522B1/en not_active Expired - Lifetime
- 1989-08-18 DE DE68926746T patent/DE68926746T2/en not_active Expired - Lifetime
- 1989-08-18 WO PCT/AU1989/000350 patent/WO1990001938A1/en active IP Right Grant
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58121216A (en) * | 1982-01-13 | 1983-07-19 | Grelan Pharmaceut Co Ltd | Phosphorus-containing mannan |
US4761402A (en) * | 1985-08-19 | 1988-08-02 | Bioglucans, L.P. | Methods and compositions for prophylactic and therapeutic treatment of infections |
JPS63119427A (en) * | 1986-11-05 | 1988-05-24 | Kao Corp | Antiallergic agent |
Non-Patent Citations (5)
Title |
---|
H.DAVID FISCHER et al, "Binding of Phosphorylated Oligosaccharides toImmobilized Phosphomannosyl Receptors" see pages 9938 to 9943 * |
PATENT ABSTRACTS OF JAPAN, vol. 12, no. 365 (C-532)[3212], 29th September 1988; & JP-A-63 119 427 (KAO) 24-05-1988 * |
PATENT ABSTRACTS OF JAPAN, vol. 7, no. 225 (C-189)[1370], 6th October 1983; & JP-A-58 121 216 (GRELAN SEIYAKU) 19-07-1983 * |
See also references of WO9001938A1 * |
THE JOURNAL OF IMMUNOLOGY, vol. 134, no. 1, January 1985, pages 65-69; H.-D. HAUBECK et al.: "Natural killer cell-mediated cytotoxicity does not depend on recognition of mannose 6-phosphate residues" * |
Also Published As
Publication number | Publication date |
---|---|
ATE139699T1 (en) | 1996-07-15 |
EP0429522B1 (en) | 1996-06-26 |
EP0429522A4 (en) | 1991-09-11 |
DE68926746D1 (en) | 1996-08-01 |
WO1990001938A1 (en) | 1990-03-08 |
DE68926746T2 (en) | 1996-11-28 |
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