EP0421406A3 - Apparatus and method for separating or measuring particles to be examined in a sample fluid - Google Patents

Apparatus and method for separating or measuring particles to be examined in a sample fluid Download PDF

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Publication number
EP0421406A3
EP0421406A3 EP19900119008 EP90119008A EP0421406A3 EP 0421406 A3 EP0421406 A3 EP 0421406A3 EP 19900119008 EP19900119008 EP 19900119008 EP 90119008 A EP90119008 A EP 90119008A EP 0421406 A3 EP0421406 A3 EP 0421406A3
Authority
EP
European Patent Office
Prior art keywords
examined
separating
sample fluid
measuring particles
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP19900119008
Other versions
EP0421406B1 (en
EP0421406A2 (en
Inventor
Naoki Yuguchi
Yoshito Yoneyama
Junichi Yamayoshi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Canon Inc
Original Assignee
Canon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1260707A external-priority patent/JP2749906B2/en
Priority claimed from JP2157015A external-priority patent/JPH0448245A/en
Application filed by Canon Inc filed Critical Canon Inc
Publication of EP0421406A2 publication Critical patent/EP0421406A2/en
Publication of EP0421406A3 publication Critical patent/EP0421406A3/en
Application granted granted Critical
Publication of EP0421406B1 publication Critical patent/EP0421406B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G01N2015/0238—Single particle scatter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
EP90119008A 1989-10-04 1990-10-04 Apparatus and method for separating or measuring particles to be examined in a sample fluid Expired - Lifetime EP0421406B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP1260707A JP2749906B2 (en) 1989-10-04 1989-10-04 Particle measurement device
JP260707/89 1989-10-04
JP157015/89 1990-06-15
JP2157015A JPH0448245A (en) 1990-06-15 1990-06-15 Particle measuring instrument

Publications (3)

Publication Number Publication Date
EP0421406A2 EP0421406A2 (en) 1991-04-10
EP0421406A3 true EP0421406A3 (en) 1992-01-15
EP0421406B1 EP0421406B1 (en) 1996-02-14

Family

ID=26484605

Family Applications (1)

Application Number Title Priority Date Filing Date
EP90119008A Expired - Lifetime EP0421406B1 (en) 1989-10-04 1990-10-04 Apparatus and method for separating or measuring particles to be examined in a sample fluid

Country Status (2)

Country Link
EP (1) EP0421406B1 (en)
DE (1) DE69025370T2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0610900A (en) * 1992-04-27 1994-01-21 Canon Inc Method and device for moving liquid and measuring device utilizing these method and device
US5958342A (en) * 1996-05-17 1999-09-28 Incyte Pharmaceuticals, Inc. Jet droplet device
US7590853B1 (en) 1996-08-12 2009-09-15 Intertrust Technologies Corporation Systems and methods using cryptography to protect secure computing environments
FR2764384B1 (en) * 1997-06-06 1999-07-16 Commissariat Energie Atomique SURFACE TREATMENT OF A SUBSTRATE LIMITING ITS NATURAL FLUORESCENCE
FR2764386B1 (en) * 1997-06-06 1999-07-16 Commissariat Energie Atomique ELECTRODES HOLDER COMPRISING AT LEAST ONE ELECTRODE COVERED BY A DEPOSIT AND READING SYSTEM THEREOF
GB0106349D0 (en) * 2001-03-14 2001-05-02 Facility Monitoring Systems Lt Detector for particle counting
DE10222228A1 (en) 2002-05-16 2003-11-27 Roche Diagnostics Gmbh Micropump with heating elements for pulsed operation
WO2011154042A1 (en) 2010-06-10 2011-12-15 Albert-Ludwigs-Universität Freiburg Apparatus and method for dispensing cells or particles confined in a free flying droplet
DE102015202574A1 (en) 2015-02-12 2016-08-18 Albert-Ludwigs-Universität Freiburg Apparatus and method for dispensing particles aligned using an acoustic field in free-flying drops
DE102016015746A1 (en) 2016-06-21 2017-12-28 Cytena Gmbh Apparatus and method for detecting cells or particles in a fluid container
DE102016211038A1 (en) 2016-06-21 2017-12-21 Cytena Gmbh Apparatus and method for detecting cells or particles in a fluid container
LU100777B1 (en) 2018-04-23 2019-10-23 Cytena Gmbh A method of assaying a liquid containing at least one cell and / or at least one particle
WO2023191806A1 (en) * 2022-04-01 2023-10-05 Hewlett-Packard Development Company, L.P. Cell-isolating dispensers

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3380584A (en) * 1965-06-04 1968-04-30 Atomic Energy Commission Usa Particle separator
US4318483A (en) * 1979-08-20 1982-03-09 Ortho Diagnostics, Inc. Automatic relative droplet charging time delay system for an electrostatic particle sorting system using a relatively moveable stream surface sensing system
EP0119573A1 (en) * 1983-03-21 1984-09-26 Miles Laboratories, Inc. Microdroplet dispensing apparatus and method
US4546360A (en) * 1983-12-16 1985-10-08 Xerox Corporation Electrothermic ink jet
WO1987000282A1 (en) * 1985-07-10 1987-01-15 Harald Steen A flow chamber device for flow cytometers
EP0268237A2 (en) * 1986-11-17 1988-05-25 Abbott Laboratories Apparatus and process for reagent fluid dispensing and printing
US4934564A (en) * 1989-03-23 1990-06-19 Eastman Kodak Company Drop jet metering method and system

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3380584A (en) * 1965-06-04 1968-04-30 Atomic Energy Commission Usa Particle separator
US4318483A (en) * 1979-08-20 1982-03-09 Ortho Diagnostics, Inc. Automatic relative droplet charging time delay system for an electrostatic particle sorting system using a relatively moveable stream surface sensing system
EP0119573A1 (en) * 1983-03-21 1984-09-26 Miles Laboratories, Inc. Microdroplet dispensing apparatus and method
US4546360A (en) * 1983-12-16 1985-10-08 Xerox Corporation Electrothermic ink jet
WO1987000282A1 (en) * 1985-07-10 1987-01-15 Harald Steen A flow chamber device for flow cytometers
EP0268237A2 (en) * 1986-11-17 1988-05-25 Abbott Laboratories Apparatus and process for reagent fluid dispensing and printing
US4934564A (en) * 1989-03-23 1990-06-19 Eastman Kodak Company Drop jet metering method and system

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF IMAGING TECHNOLOGY, vol. 14, no. 5, October 1988, pages 120-124, SPSE - The Society of Imaging Science and Technology, Springfield, VA, US; A. ASAI et al.: "Bubble generation mechanism in the bubble jet recording process" *

Also Published As

Publication number Publication date
EP0421406B1 (en) 1996-02-14
EP0421406A2 (en) 1991-04-10
DE69025370D1 (en) 1996-03-28
DE69025370T2 (en) 1996-09-12

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