EP0421406A3 - Apparatus and method for separating or measuring particles to be examined in a sample fluid - Google Patents
Apparatus and method for separating or measuring particles to be examined in a sample fluid Download PDFInfo
- Publication number
- EP0421406A3 EP0421406A3 EP19900119008 EP90119008A EP0421406A3 EP 0421406 A3 EP0421406 A3 EP 0421406A3 EP 19900119008 EP19900119008 EP 19900119008 EP 90119008 A EP90119008 A EP 90119008A EP 0421406 A3 EP0421406 A3 EP 0421406A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- examined
- separating
- sample fluid
- measuring particles
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012530 fluid Substances 0.000 title 1
- 239000002245 particle Substances 0.000 title 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
- B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/02—Investigating particle size or size distribution
- G01N15/0205—Investigating particle size or size distribution by optical means
- G01N2015/0238—Single particle scatter
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Clinical Laboratory Science (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1260707A JP2749906B2 (en) | 1989-10-04 | 1989-10-04 | Particle measurement device |
JP260707/89 | 1989-10-04 | ||
JP157015/89 | 1990-06-15 | ||
JP2157015A JPH0448245A (en) | 1990-06-15 | 1990-06-15 | Particle measuring instrument |
Publications (3)
Publication Number | Publication Date |
---|---|
EP0421406A2 EP0421406A2 (en) | 1991-04-10 |
EP0421406A3 true EP0421406A3 (en) | 1992-01-15 |
EP0421406B1 EP0421406B1 (en) | 1996-02-14 |
Family
ID=26484605
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP90119008A Expired - Lifetime EP0421406B1 (en) | 1989-10-04 | 1990-10-04 | Apparatus and method for separating or measuring particles to be examined in a sample fluid |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP0421406B1 (en) |
DE (1) | DE69025370T2 (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0610900A (en) * | 1992-04-27 | 1994-01-21 | Canon Inc | Method and device for moving liquid and measuring device utilizing these method and device |
US5958342A (en) * | 1996-05-17 | 1999-09-28 | Incyte Pharmaceuticals, Inc. | Jet droplet device |
US7590853B1 (en) | 1996-08-12 | 2009-09-15 | Intertrust Technologies Corporation | Systems and methods using cryptography to protect secure computing environments |
FR2764384B1 (en) * | 1997-06-06 | 1999-07-16 | Commissariat Energie Atomique | SURFACE TREATMENT OF A SUBSTRATE LIMITING ITS NATURAL FLUORESCENCE |
FR2764386B1 (en) * | 1997-06-06 | 1999-07-16 | Commissariat Energie Atomique | ELECTRODES HOLDER COMPRISING AT LEAST ONE ELECTRODE COVERED BY A DEPOSIT AND READING SYSTEM THEREOF |
GB0106349D0 (en) * | 2001-03-14 | 2001-05-02 | Facility Monitoring Systems Lt | Detector for particle counting |
DE10222228A1 (en) | 2002-05-16 | 2003-11-27 | Roche Diagnostics Gmbh | Micropump with heating elements for pulsed operation |
WO2011154042A1 (en) | 2010-06-10 | 2011-12-15 | Albert-Ludwigs-Universität Freiburg | Apparatus and method for dispensing cells or particles confined in a free flying droplet |
DE102015202574A1 (en) | 2015-02-12 | 2016-08-18 | Albert-Ludwigs-Universität Freiburg | Apparatus and method for dispensing particles aligned using an acoustic field in free-flying drops |
DE102016015746A1 (en) | 2016-06-21 | 2017-12-28 | Cytena Gmbh | Apparatus and method for detecting cells or particles in a fluid container |
DE102016211038A1 (en) | 2016-06-21 | 2017-12-21 | Cytena Gmbh | Apparatus and method for detecting cells or particles in a fluid container |
LU100777B1 (en) | 2018-04-23 | 2019-10-23 | Cytena Gmbh | A method of assaying a liquid containing at least one cell and / or at least one particle |
WO2023191806A1 (en) * | 2022-04-01 | 2023-10-05 | Hewlett-Packard Development Company, L.P. | Cell-isolating dispensers |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3380584A (en) * | 1965-06-04 | 1968-04-30 | Atomic Energy Commission Usa | Particle separator |
US4318483A (en) * | 1979-08-20 | 1982-03-09 | Ortho Diagnostics, Inc. | Automatic relative droplet charging time delay system for an electrostatic particle sorting system using a relatively moveable stream surface sensing system |
EP0119573A1 (en) * | 1983-03-21 | 1984-09-26 | Miles Laboratories, Inc. | Microdroplet dispensing apparatus and method |
US4546360A (en) * | 1983-12-16 | 1985-10-08 | Xerox Corporation | Electrothermic ink jet |
WO1987000282A1 (en) * | 1985-07-10 | 1987-01-15 | Harald Steen | A flow chamber device for flow cytometers |
EP0268237A2 (en) * | 1986-11-17 | 1988-05-25 | Abbott Laboratories | Apparatus and process for reagent fluid dispensing and printing |
US4934564A (en) * | 1989-03-23 | 1990-06-19 | Eastman Kodak Company | Drop jet metering method and system |
-
1990
- 1990-10-04 EP EP90119008A patent/EP0421406B1/en not_active Expired - Lifetime
- 1990-10-04 DE DE69025370T patent/DE69025370T2/en not_active Expired - Fee Related
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3380584A (en) * | 1965-06-04 | 1968-04-30 | Atomic Energy Commission Usa | Particle separator |
US4318483A (en) * | 1979-08-20 | 1982-03-09 | Ortho Diagnostics, Inc. | Automatic relative droplet charging time delay system for an electrostatic particle sorting system using a relatively moveable stream surface sensing system |
EP0119573A1 (en) * | 1983-03-21 | 1984-09-26 | Miles Laboratories, Inc. | Microdroplet dispensing apparatus and method |
US4546360A (en) * | 1983-12-16 | 1985-10-08 | Xerox Corporation | Electrothermic ink jet |
WO1987000282A1 (en) * | 1985-07-10 | 1987-01-15 | Harald Steen | A flow chamber device for flow cytometers |
EP0268237A2 (en) * | 1986-11-17 | 1988-05-25 | Abbott Laboratories | Apparatus and process for reagent fluid dispensing and printing |
US4934564A (en) * | 1989-03-23 | 1990-06-19 | Eastman Kodak Company | Drop jet metering method and system |
Non-Patent Citations (1)
Title |
---|
JOURNAL OF IMAGING TECHNOLOGY, vol. 14, no. 5, October 1988, pages 120-124, SPSE - The Society of Imaging Science and Technology, Springfield, VA, US; A. ASAI et al.: "Bubble generation mechanism in the bubble jet recording process" * |
Also Published As
Publication number | Publication date |
---|---|
EP0421406B1 (en) | 1996-02-14 |
EP0421406A2 (en) | 1991-04-10 |
DE69025370D1 (en) | 1996-03-28 |
DE69025370T2 (en) | 1996-09-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 19910102 |
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AK | Designated contracting states |
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PUAL | Search report despatched |
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EN | Fr: translation not filed | ||
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STAA | Information on the status of an ep patent application or granted ep patent |
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26N | No opposition filed | ||
GBPC | Gb: european patent ceased through non-payment of renewal fee |
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