EP0391892A4 - Nonglycosylated analogs of human colony stimulating factors - Google Patents

Nonglycosylated analogs of human colony stimulating factors

Info

Publication number
EP0391892A4
EP0391892A4 EP19870907559 EP87907559A EP0391892A4 EP 0391892 A4 EP0391892 A4 EP 0391892A4 EP 19870907559 EP19870907559 EP 19870907559 EP 87907559 A EP87907559 A EP 87907559A EP 0391892 A4 EP0391892 A4 EP 0391892A4
Authority
EP
European Patent Office
Prior art keywords
nonglycosylated
analogs
colony stimulating
stimulating factors
human colony
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19870907559
Other versions
EP0391892A1 (en
Inventor
Michael Deeley
Virginia L. Price
David Urdal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunex Corp
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Publication of EP0391892A1 publication Critical patent/EP0391892A1/en
Publication of EP0391892A4 publication Critical patent/EP0391892A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP19870907559 1987-10-30 1987-10-30 Nonglycosylated analogs of human colony stimulating factors Withdrawn EP0391892A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1987/002799 WO1989003881A1 (en) 1987-10-30 1987-10-30 Nonglycosylated analogs of human colony stimulating factors

Publications (2)

Publication Number Publication Date
EP0391892A1 EP0391892A1 (en) 1990-10-17
EP0391892A4 true EP0391892A4 (en) 1990-11-28

Family

ID=22202635

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19870907559 Withdrawn EP0391892A4 (en) 1987-10-30 1987-10-30 Nonglycosylated analogs of human colony stimulating factors

Country Status (3)

Country Link
EP (1) EP0391892A4 (en)
JP (1) JPH03502322A (en)
WO (1) WO1989003881A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5153310A (en) * 1989-02-28 1992-10-06 Du Pont Merck Pharmaceutical Company Il-2 analogs containing n-linked glycosylation sites
EP0646643B1 (en) * 1993-06-30 2001-12-05 Lucky Ltd. Modified human granulocyte macrophage-colony stimulating factor gene and expression thereof in yeast
CN1044720C (en) * 1993-07-07 1999-08-18 株式会社乐喜 Modified human granulocyte macrophagecolony stimulating factor gene and expression thereof in yeast
NZ321039A (en) 1995-10-04 2001-03-30 Immunex Corp Use of flt3-ligand to augment immunizing effects of known cytokines by stimulating myeloid precursor cells, monocytic cells, macrophages, B-cells and dendritic cells from CD34+ bone marrow progenitors
CN102351952B (en) * 2011-10-19 2015-07-01 中国医学科学院基础医学研究所 Low-saccharification mutant interferon lambda1 as well as expression and purification methods and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0212914A2 (en) * 1985-08-06 1987-03-04 Immunex Corporation Amplifying the expression of recombinant DNA products

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63502795A (en) * 1985-10-03 1988-10-20 バイオジェン インコーポレイテッド Granulocyte-macrophage colony-stimulating factor-like polypeptides, DNA sequences, recombinant DNA molecules and methods for producing high yields of human granulocyte-macrophage colony-stimulating factor-like polypeptides in microbial cells.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0212914A2 (en) * 1985-08-06 1987-03-04 Immunex Corporation Amplifying the expression of recombinant DNA products

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BIOTECHNOLOGY, vol. 5, no. 8, August 1987, pages 831-834, New York, US; J.F. ERNST et al.: "0-glycosylation and novel processing events during secretion of aplha-factor/GM-CSF fusions by saccharomyces cerevisiae" *
See also references of WO8903881A1 *

Also Published As

Publication number Publication date
JPH03502322A (en) 1991-05-30
WO1989003881A1 (en) 1989-05-05
EP0391892A1 (en) 1990-10-17

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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