EP0347435A4 - Dna sequences, recombinant dna molecules and processes for producing soluble t4 proteins - Google Patents
Dna sequences, recombinant dna molecules and processes for producing soluble t4 proteinsInfo
- Publication number
- EP0347435A4 EP0347435A4 EP19880908543 EP88908543A EP0347435A4 EP 0347435 A4 EP0347435 A4 EP 0347435A4 EP 19880908543 EP19880908543 EP 19880908543 EP 88908543 A EP88908543 A EP 88908543A EP 0347435 A4 EP0347435 A4 EP 0347435A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- proteins
- processes
- producing soluble
- recombinant dna
- dna sequences
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70514—CD4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2812—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
- G01N33/56988—HIV or HTLV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15051—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- AIDS & HIV (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Analytical Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- General Physics & Mathematics (AREA)
- Transplantation (AREA)
- Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9432287A | 1987-09-04 | 1987-09-04 | |
US94322 | 1987-09-04 | ||
US14164988A | 1988-01-07 | 1988-01-07 | |
US141649 | 1988-01-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0347435A1 EP0347435A1 (en) | 1989-12-27 |
EP0347435A4 true EP0347435A4 (en) | 1991-11-21 |
Family
ID=26788733
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19880908543 Withdrawn EP0347435A4 (en) | 1987-09-04 | 1988-09-01 | Dna sequences, recombinant dna molecules and processes for producing soluble t4 proteins |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0347435A4 (en) |
JP (1) | JPH02501192A (en) |
KR (1) | KR890701605A (en) |
DK (1) | DK216589A (en) |
ES (1) | ES2013346A6 (en) |
GR (1) | GR1000489B (en) |
IL (1) | IL87647A0 (en) |
NO (1) | NO891818L (en) |
NZ (1) | NZ226040A (en) |
OA (1) | OA09625A (en) |
PT (1) | PT88425B (en) |
WO (1) | WO1989001940A1 (en) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU616639B2 (en) | 1986-08-21 | 1991-11-07 | Trustees Of Columbia University In The City Of New York, The | Dna encoding the t cell surface protein t4 and use of fragments of t4 in the treatment of aids |
US5958678A (en) * | 1986-08-21 | 1999-09-28 | The Trustees Of Columbia University In The City Of New York | DNA encoding the T cell surface protein T4 and use of fragments of T4 in the treatment of AIDS |
ZA887365B (en) * | 1987-10-02 | 1990-05-30 | Genentech Inc | Adheson variants |
US5336603A (en) * | 1987-10-02 | 1994-08-09 | Genentech, Inc. | CD4 adheson variants |
US6710169B2 (en) | 1987-10-02 | 2004-03-23 | Genentech, Inc. | Adheson variants |
PT89484B (en) * | 1988-01-22 | 1994-03-31 | Gen Hospital Corp | GENE CLONED CODES OF FUSAO PROTEINS IG-CD4 AND ITS UTILIZATION |
US6004781A (en) * | 1988-01-22 | 1999-12-21 | The General Hospital Corporation | Nucleic acid encoding Ig-CD4 fusion proteins |
AU3006789A (en) * | 1988-02-24 | 1989-08-24 | Smithkline Beckman Corporation | Expression of hiv binding proteins |
EP0346091A3 (en) * | 1988-06-10 | 1990-09-12 | Dana Farber Cancer Institute | Method of diagnosis for naturally occurring antibodies to cd4 |
WO1990005534A1 (en) * | 1988-11-23 | 1990-05-31 | Genentech, Inc. | Polypeptide derivatives |
WO1990012031A1 (en) * | 1989-04-05 | 1990-10-18 | The Upjohn Company | SOLUBLE CD4 PRODUCED IN $i(E. COLI) |
EP0408372A1 (en) * | 1989-07-13 | 1991-01-16 | Smithkline Beecham Corporation | Anti-viral therapy |
WO1991002743A1 (en) * | 1989-08-23 | 1991-03-07 | The General Hospital Corporation | Non-human primate cd4 polypeptides, fusions thereof, dna encoding, and uses thereof |
US5180820A (en) * | 1989-08-30 | 1993-01-19 | Barde Yves Alain | Brain-derived neurotrophic factor |
JPH0725794B2 (en) * | 1990-03-23 | 1995-03-22 | 呉羽化学工業株式会社 | Novel peptide |
WO1991018618A2 (en) * | 1990-05-25 | 1991-12-12 | Biogen, Inc. | Immunotherapeutic compositions for treating and preventing aids, arc and hiv infection |
WO1992009305A1 (en) * | 1990-11-27 | 1992-06-11 | Biogen, Inc. | Anti cd-4 antibodies blocking hiv-induced syncytia |
US7070991B2 (en) | 1991-02-08 | 2006-07-04 | Progenics Pharmaceuticals, Inc. | Cells expressing a CD4-IgG2 chimeric heterotetramer |
WO1992013947A1 (en) | 1991-02-08 | 1992-08-20 | Progenics Pharmaceuticals, Inc. | CD4-GAMMA2 AND CD4-IgG2 CHIMERAS |
AU1438592A (en) * | 1991-02-08 | 1992-09-07 | Progenics Pharmaceuticals, Inc. | Cd4-gamma1 and cd4-igg1 chimeras |
US5389529A (en) * | 1991-06-12 | 1995-02-14 | Regeneron Pharmaceuticals, Inc. | Modified lamβ signal sequence and processes for producing recombinant neurotrophins |
GB9219562D0 (en) | 1992-03-11 | 1992-10-28 | Prendergast Kennet F | Anti-viral peptides |
CA2204121C (en) * | 1994-11-04 | 2010-12-21 | Elizabeth Ehrenfeld | Medium for detecting target microbes in a sample |
US5635363A (en) | 1995-02-28 | 1997-06-03 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for the detection, quantitation and purification of antigen-specific T cells |
WO1996040726A1 (en) | 1995-06-07 | 1996-12-19 | Genta Incorporated | Novel carbamate-based cationic lipids |
ES2299276T3 (en) | 1998-12-31 | 2008-05-16 | Novartis Vaccines And Diagnostics, Inc. | MODIFIED HIV ENV POLIPEPTIDES. |
US7935805B1 (en) | 1998-12-31 | 2011-05-03 | Novartis Vaccines & Diagnostics, Inc | Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof |
CA2358385C (en) | 1998-12-31 | 2013-08-06 | Chiron Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
WO2000039302A2 (en) | 1998-12-31 | 2000-07-06 | Chiron Corporation | Improved expression of hiv polypeptides and production of virus-like particles |
WO2003004620A2 (en) | 2001-07-05 | 2003-01-16 | Chiron, Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
WO2003020876A2 (en) | 2001-08-31 | 2003-03-13 | Chiron Corporation | Polynucleotides encoding antigenic hiv type b polypeptides, polypeptides and uses thereof |
US20030170614A1 (en) | 2001-08-31 | 2003-09-11 | Megede Jan Zur | Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof |
CN113209124B (en) * | 2021-02-24 | 2022-04-15 | 四川大学 | Application of DNA tetrahedron in preparation of medicines for preventing and treating type 1 diabetes |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988001304A1 (en) * | 1986-08-21 | 1988-02-25 | The Trustees Of Columbia University In The City Of | Dna encoding the t cell surface protein t4 and use of fragments of t4 in the treatment of aids |
WO1989001779A1 (en) * | 1987-08-30 | 1989-03-09 | Gershoni Jonathan M | Molecular decoyants and methods of use thereof |
WO1989002922A1 (en) * | 1987-10-02 | 1989-04-06 | Genentech, Inc. | Adheson variants |
-
1988
- 1988-09-01 KR KR1019890700813A patent/KR890701605A/en not_active Application Discontinuation
- 1988-09-01 IL IL87647A patent/IL87647A0/en unknown
- 1988-09-01 WO PCT/US1988/002940 patent/WO1989001940A1/en not_active Application Discontinuation
- 1988-09-01 EP EP19880908543 patent/EP0347435A4/en not_active Withdrawn
- 1988-09-01 JP JP63507739A patent/JPH02501192A/en active Pending
- 1988-09-05 GR GR880100579A patent/GR1000489B/en unknown
- 1988-09-05 PT PT88425A patent/PT88425B/en not_active IP Right Cessation
- 1988-09-05 NZ NZ226040A patent/NZ226040A/en unknown
- 1988-09-05 ES ES8802727A patent/ES2013346A6/en not_active Expired - Lifetime
-
1989
- 1989-05-02 NO NO89891818A patent/NO891818L/en unknown
- 1989-05-03 DK DK216589A patent/DK216589A/en not_active Application Discontinuation
-
1990
- 1990-03-01 OA OA59745A patent/OA09625A/en unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988001304A1 (en) * | 1986-08-21 | 1988-02-25 | The Trustees Of Columbia University In The City Of | Dna encoding the t cell surface protein t4 and use of fragments of t4 in the treatment of aids |
WO1989001779A1 (en) * | 1987-08-30 | 1989-03-09 | Gershoni Jonathan M | Molecular decoyants and methods of use thereof |
WO1989002922A1 (en) * | 1987-10-02 | 1989-04-06 | Genentech, Inc. | Adheson variants |
Non-Patent Citations (1)
Title |
---|
See also references of WO8901940A1 * |
Also Published As
Publication number | Publication date |
---|---|
KR890701605A (en) | 1989-12-21 |
GR1000489B (en) | 1992-07-30 |
NZ226040A (en) | 1992-02-25 |
PT88425A (en) | 1989-07-31 |
NO891818D0 (en) | 1989-05-02 |
DK216589A (en) | 1989-07-04 |
ES2013346A6 (en) | 1990-05-01 |
GR880100579A (en) | 1989-06-22 |
EP0347435A1 (en) | 1989-12-27 |
WO1989001940A1 (en) | 1989-03-09 |
IL87647A0 (en) | 1989-02-28 |
NO891818L (en) | 1989-07-03 |
OA09625A (en) | 1993-04-30 |
AU2482988A (en) | 1989-03-31 |
DK216589D0 (en) | 1989-05-03 |
JPH02501192A (en) | 1990-04-26 |
PT88425B (en) | 1992-10-30 |
AU626007B2 (en) | 1992-07-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19890420 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE FR GB IT LI LU NL SE |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: GILBERT, WALTER Inventor name: SATO, VICKI, L. Inventor name: MARAGANORE, JOHN, M. Inventor name: FLAVELL, RICHARD, A. Inventor name: FISHER, RICHARD, A. Inventor name: LIU, THERESA, R. |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19910930 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE FR GB IT LI LU NL SE |
|
17Q | First examination report despatched |
Effective date: 19920217 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 19930108 |