EP0343388A3 - Expression of interferon-gamma in methylotrophic yeasts - Google Patents

Expression of interferon-gamma in methylotrophic yeasts Download PDF

Info

Publication number
EP0343388A3
EP0343388A3 EP19890107460 EP89107460A EP0343388A3 EP 0343388 A3 EP0343388 A3 EP 0343388A3 EP 19890107460 EP19890107460 EP 19890107460 EP 89107460 A EP89107460 A EP 89107460A EP 0343388 A3 EP0343388 A3 EP 0343388A3
Authority
EP
European Patent Office
Prior art keywords
interferon
gamma
expression
methylotrophic yeasts
methylotrophic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19890107460
Other languages
German (de)
English (en)
French (fr)
Other versions
EP0343388A2 (en
Inventor
Gregory Patrick Thill
Geneva Ruth Davis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phillips Petroleum Co
Original Assignee
Phillips Petroleum Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phillips Petroleum Co filed Critical Phillips Petroleum Co
Publication of EP0343388A2 publication Critical patent/EP0343388A2/en
Publication of EP0343388A3 publication Critical patent/EP0343388A3/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP19890107460 1988-04-25 1989-04-25 Expression of interferon-gamma in methylotrophic yeasts Withdrawn EP0343388A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18521988A 1988-04-25 1988-04-25
US185219 1988-04-25

Publications (2)

Publication Number Publication Date
EP0343388A2 EP0343388A2 (en) 1989-11-29
EP0343388A3 true EP0343388A3 (en) 1990-09-12

Family

ID=22680096

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19890107460 Withdrawn EP0343388A3 (en) 1988-04-25 1989-04-25 Expression of interferon-gamma in methylotrophic yeasts

Country Status (6)

Country Link
EP (1) EP0343388A3 (da)
JP (1) JPH02242694A (da)
AU (1) AU3337589A (da)
DK (1) DK200089A (da)
IL (1) IL90021A0 (da)
NO (1) NO891715L (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2000231863A1 (en) * 2000-03-16 2001-09-24 Shantha Biotechnics (P) Ltd. A process for the production of human interferon alpha from genetically engineered yeast
CA2484251C (en) 2002-04-30 2015-06-23 University Of South Florida Materials and methods for inhibition of respiratory syncytial virus infection
US7595303B1 (en) 2002-09-05 2009-09-29 University Of South Florida Genetic adjuvants for immunotherapy
CN100340656C (zh) * 2002-09-06 2007-10-03 上海擎天生物制药技术开发有限公司 人γ－干扰素在毕赤酵母菌中的高效表达、发酵和纯化

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0077670A2 (en) * 1981-10-19 1983-04-27 Genentech, Inc. Human immune interferon
EP0139878A2 (en) * 1981-04-17 1985-05-08 Meloy Laboratories, Inc. Production of immune interferon and its mRNA
EP0183071A2 (en) * 1984-10-30 1986-06-04 Phillips Petroleum Company Regulatory region for heterologous gene expression in yeast
EP0188677A2 (en) * 1984-10-30 1986-07-30 Phillips Petroleum Company Genes from pichia histidine pathway and uses thereof
EP0226846A1 (en) * 1985-11-26 1987-07-01 Phillips Petroleum Company Yeast production of hepatitis B Surface antigen
EP0226752A1 (en) * 1985-10-25 1987-07-01 Research Corporation Technologies, Inc. Method for high-level expression of polypeptides in yeast of the genus Pichia
EP0256421A2 (en) * 1986-08-12 1988-02-24 Phillips Petroleum Company Secretion of heterologous proteins from yeast

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0139878A2 (en) * 1981-04-17 1985-05-08 Meloy Laboratories, Inc. Production of immune interferon and its mRNA
EP0077670A2 (en) * 1981-10-19 1983-04-27 Genentech, Inc. Human immune interferon
EP0183071A2 (en) * 1984-10-30 1986-06-04 Phillips Petroleum Company Regulatory region for heterologous gene expression in yeast
EP0188677A2 (en) * 1984-10-30 1986-07-30 Phillips Petroleum Company Genes from pichia histidine pathway and uses thereof
EP0226752A1 (en) * 1985-10-25 1987-07-01 Research Corporation Technologies, Inc. Method for high-level expression of polypeptides in yeast of the genus Pichia
EP0226846A1 (en) * 1985-11-26 1987-07-01 Phillips Petroleum Company Yeast production of hepatitis B Surface antigen
EP0256421A2 (en) * 1986-08-12 1988-02-24 Phillips Petroleum Company Secretion of heterologous proteins from yeast

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NATURE *

Also Published As

Publication number Publication date
EP0343388A2 (en) 1989-11-29
NO891715D0 (no) 1989-04-25
IL90021A0 (en) 1989-12-15
NO891715L (no) 1989-10-26
AU3337589A (en) 1989-10-26
JPH02242694A (ja) 1990-09-27
DK200089D0 (da) 1989-04-25
DK200089A (da) 1989-10-26

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