EP0302103A4 - Colony stimulating factors having reduced levels of carbohydrate. - Google Patents

Colony stimulating factors having reduced levels of carbohydrate.

Info

Publication number
EP0302103A4
EP0302103A4 EP19880902287 EP88902287A EP0302103A4 EP 0302103 A4 EP0302103 A4 EP 0302103A4 EP 19880902287 EP19880902287 EP 19880902287 EP 88902287 A EP88902287 A EP 88902287A EP 0302103 A4 EP0302103 A4 EP 0302103A4
Authority
EP
European Patent Office
Prior art keywords
carbohydrate
colony stimulating
reduced levels
stimulating factors
factors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19880902287
Other languages
German (de)
French (fr)
Other versions
EP0302103A1 (en
Inventor
Steven C Clark
Gordon G Wong
Robert E Donahue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetics Institute LLC
Original Assignee
Applied Bio Technology Inc
APPLIED BIOTECHNOLOGIES Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Bio Technology Inc, APPLIED BIOTECHNOLOGIES Inc filed Critical Applied Bio Technology Inc
Publication of EP0302103A1 publication Critical patent/EP0302103A1/en
Publication of EP0302103A4 publication Critical patent/EP0302103A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP19880902287 1987-02-06 1988-02-05 Colony stimulating factors having reduced levels of carbohydrate. Withdrawn EP0302103A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1179487A 1987-02-06 1987-02-06
US11794 1987-02-06

Publications (2)

Publication Number Publication Date
EP0302103A1 EP0302103A1 (en) 1989-02-08
EP0302103A4 true EP0302103A4 (en) 1989-06-21

Family

ID=21751992

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19880902287 Withdrawn EP0302103A4 (en) 1987-02-06 1988-02-05 Colony stimulating factors having reduced levels of carbohydrate.

Country Status (4)

Country Link
EP (1) EP0302103A4 (en)
JP (1) JPH01502196A (en)
AU (1) AU1369088A (en)
WO (1) WO1988005786A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5104650A (en) * 1985-02-05 1992-04-14 Cetus Corporation Uses of recombinant colony stimulating factor-1
US5422105A (en) * 1985-02-05 1995-06-06 Cetus Oncology Corporation Use of recombinant colony stimulating factor 1
US5837229A (en) * 1985-02-05 1998-11-17 Chiron Corporation Uses of recombinant colony stimulating factor-1
US5556620A (en) * 1985-02-05 1996-09-17 Cetus Oncology Corporation Use of recombinant colony stimulating factor-1 to enhance wound healing
AU615550B2 (en) * 1988-04-21 1991-10-03 Medvet Science Pty. Ltd. Human gm-csf variants
ES2105972B1 (en) * 1995-08-03 1998-06-01 Cantabria Ind Farmaceutica Sa A PROCEDURE FOR THE OBTAINING OF BIOLOGICAL RESPONSE MODIFIERS WITH RECOVERY ACTIVITY OF THE HEMATOPOYETIC FUNCTION FROM, EQUALLY AND INDISTINCATELY, TWO BACTERIAL STRAINS FIXING N2 AZOTOBACTER CHROOCOCCUM AND VINEL AZOTOBACTER.
CA2673560C (en) * 2006-12-22 2017-08-22 The Regents Of The University Of California New fusion molecule based on novel taa variant

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4518584A (en) * 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BIOCHEMISTRY, vol. 26, no. 15, 28th July 1987, pages 4861-4867, American Chemical Society, Washington, DC, US; K. KAUSHANSKY: "Role of carbohydrate in the function of human granulocyte-macrophage colony-stimulating factor" *
CHEMICAL ABSTRACTS, vol. 106, no. 17, 27th April 1987, page 562, abstract no. 136909t, Columbus, Ohio, US; W.A. BURGESS et al.: "Purification and properties of bacterially synthesized human granulocyte-macrophage colony stimulating factor", & BLOOD 1987, 69(1), 43-51 *
CHEMICAL ABSTRACTS, vol. 106, no. 17, 27th April 1987, page 77, abstract no. 131875u, Columbus, Ohio, US; J.H. SHIEH: "Purification and characterization of human colony-stimulating factor 1 from human pancreatic carcinoma (MIA PaCa-2) cells", & ARCH. BIOCHEM. BIOPHYS. 1987, 253(1), 205-13 *
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 84, no. 13, July 1987, pages 4428-4431; P. MOONEN et al.: "Increased biological activity of deglycosylated recombinant human granulocyte/macrophage colony-stimulating factor produced by yeast or animal cells" *
See also references of WO8805786A1 *
THE EMBO JOURNAL, vol. 5, no. 6, 1986, pages 1193-1197; A. Miyajima et al.: "Expression of murine and human granulocyte-macrophage colony-stimulating factors in S. cerevisiae: mutagenesis of the potential glycosylation sites" *

Also Published As

Publication number Publication date
JPH01502196A (en) 1989-08-03
AU1369088A (en) 1988-08-24
EP0302103A1 (en) 1989-02-08
WO1988005786A1 (en) 1988-08-11

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): DE FR GB

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: GENETICS INSTITUTE, INC.

17P Request for examination filed

Effective date: 19890210

A4 Supplementary search report drawn up and despatched

Effective date: 19890621

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN

18W Application withdrawn

Withdrawal date: 19910116

R18W Application withdrawn (corrected)

Effective date: 19910116