EP0262060B1 - Zentrifugenvorrichtung zum Durchführen von Analysen - Google Patents

Zentrifugenvorrichtung zum Durchführen von Analysen Download PDF

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Publication number
EP0262060B1
EP0262060B1 EP87420250A EP87420250A EP0262060B1 EP 0262060 B1 EP0262060 B1 EP 0262060B1 EP 87420250 A EP87420250 A EP 87420250A EP 87420250 A EP87420250 A EP 87420250A EP 0262060 B1 EP0262060 B1 EP 0262060B1
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EP
European Patent Office
Prior art keywords
rotor
centrifuge
rotation
plate
axis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP87420250A
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English (en)
French (fr)
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EP0262060A2 (de
EP0262060A3 (en
Inventor
Jean-Pierre Simon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kis Photo Industrie SARL
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Kis Photo Industrie SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8613552A external-priority patent/FR2605104B1/fr
Priority claimed from FR8613550A external-priority patent/FR2604925B1/fr
Priority claimed from FR8613551A external-priority patent/FR2605108B1/fr
Application filed by Kis Photo Industrie SARL filed Critical Kis Photo Industrie SARL
Publication of EP0262060A2 publication Critical patent/EP0262060A2/de
Publication of EP0262060A3 publication Critical patent/EP0262060A3/fr
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Publication of EP0262060B1 publication Critical patent/EP0262060B1/de
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Expired - Lifetime legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/02—Centrifuges consisting of a plurality of separate bowls rotating round an axis situated between the bowls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B15/00—Other accessories for centrifuges
    • B04B15/02—Other accessories for centrifuges for cooling, heating, or heat insulating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B9/00—Drives specially designed for centrifuges; Arrangement or disposition of transmission gearing; Suspending or balancing rotary bowls
    • B04B9/08—Arrangement or disposition of transmission gearing ; Couplings; Brakes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B9/00—Drives specially designed for centrifuges; Arrangement or disposition of transmission gearing; Suspending or balancing rotary bowls
    • B04B9/14—Balancing rotary bowls ; Schrappers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/111666—Utilizing a centrifuge or compartmented rotor

Definitions

  • the present invention relates to a centrifuge device for carrying out analyzes, in particular biological and medical, of samples contained in an analysis unit; the latter comprises, in a manner known per se, a reading cell for any spectrophotometric measurement in absorbance.
  • the means according to the invention allow the different analysis boxes to be pivoted gradually, smoothly, relative to the support plate. By thus avoiding any accelerated rotation of an analysis unit, one thus avoids any secondary centrifugation of the latter, relative to its own axis, which would adversely affect the quality of the analysis.
  • Figure 1 is a partially exploded perspective view of an automatic device for carrying out biological and medical analyzes, according to the invention.
  • FIG. 2 is a cross section of the planar field holographic grating spectophotometer, forming part of the device according to FIG. 1.
  • FIG. 3 is a cross section of the centrifuge system according to the invention.
  • Figure 4 is a cross section of the device, including materializing the thermostat and ventilation system.
  • Figure 5 is a cross section of the optical assembly, forming part of the spectrophotometric measurement assembly;
  • Figure 6 is a schematic perspective view of the entire device according to the invention, integrated within a housing.
  • Figure 7 is a top view, on an enlarged scale, of the pivoting means according to the invention.
  • FIGS. 8 and 9 are views illustrating the operating mode of the pivoting means according to FIG. 7.
  • Figures 10 and 11 are cross-sections illustrating the operation of a dynamic balancing device according to the invention, in the absence of an analysis unit to be centrifuged, respectively in the stop phase and in the centrifugation phase .
  • Figures 12 and 13 are cross sections illustrating the operation of the same device, in the presence of an analysis unit to be centrifuged, respectively in the stop phase and in the centrifugation phase.
  • FIG 14 shows, as in Figure 3, another centrifuge system according to the invention.
  • the automatic device for carrying out biological and medical analyzes is integrated within a box of generally parallelepiped shape having the general reference (1), observable within FIG. 6.
  • This box has on its face upper two covers respectively (2) and (3), one (2) acting as a liquid crystal screen (4) and releasing, when in the open position, a touch keyboard (5), the other (3) allowing access to the various individual supports of the centrifuge device which will be described later.
  • This cover (3) releases, when in the open position, a semi-circular orifice serving as access to the loading (7) of the analysis boxes (50) on the rotary upper plate of the centrifuge device.
  • the cover (3) has a sealing member (6), intended to fit perfectly into the access orifice (7).
  • the covers (2) and (3) can be locked by means of a locking button (8).
  • the results of the analysis are printed by means of a printer (9) located in the immediate vicinity of the liquid crystal screen (4) and the keyboard (5).
  • the entire device is in a known manner governed by a microcomputer whose software of the PROM type is observed in reference (10).
  • the housing (1) also has at its upper face a hatch (11) for changing the lamp of the optical system, also described later.
  • the upper plate (22) has five receptacles (23) each intended to receive an analysis unit (50). Within the base (24) of each of these said receptacles, a slot (25) is provided on the one hand, intended to cooperate with a part of the locking plate (21) and a semi-circular orifice (26), intended to cooperate with the pivot axis described later.
  • a circular plate (27) serving as an individual support for an analysis unit (50) has under its underside a mortise (28), intended to cooperate with a tenon (29), formed at the upper end of an axis pivot (30). Each support (27) also has two positioning pins (31), intended to cooperate with the positioning orifices provided within each of the analysis boxes.
  • the support plate (19) has a plurality of orifices (32), each intended to leave a passage for the pivot axis (30).
  • Each of these orifices (32), located on the periphery of the plate (19), is tangent by two radial ramps (33), rising from the center of the plate towards its periphery, each of these ramps (33) being intended to receive a ball said balancing ball (34).
  • These balls (34) are intended to allow dynamic balancing of the rotary assembly of the centrifuge device.
  • the support plate comprises a plurality of pairs of ascending ramps (33), from the center to the periphery, each of these ramps being radial.
  • the number of receptacles (23) present is equal to five, therefore the number of pairs of ramps (33) also.
  • Each pair of ramps (33) is arranged, in the vicinity of the periphery of the support plate (19), on either side of an orifice (32), allowing the passage of an axis (30) for pivoting the housings (50) to be centrifuged in the receptacles (23) of the upper plate (22).
  • Each of said ramps (33) receives a ball (34), made of steel, the diameter of which is a function of the mass of the desired ball. Because the ramps are ascending from the center to the periphery of the plate (19), the angle of inclination being twelve degrees (12 °) relative to the horizontal, when said plate does not rotate, the balls are located in the vicinity of the center of said plate (19), in contact with a crown (80) of limitation of the lower path of the balls, said crown surrounding the conical insert (20), for fixing on the axis of the motor (13).
  • the locking plate (21) is in the form of a corolla, the number of petals (35) coincides with the number of receptacles (23) of the upper plate (22), five in this case.
  • Each of these petals (35) or radial elements is terminated, at its free end, by a lug or stop (36) extending towards the upper plate (22), and intended to cooperate with a slot (35), formed at within the base (24) of each of the receptacles (22) of said tray (22), and this, only in the case where the receptacle (23) considered does not contain a housing (50) to be centrifuged.
  • each petal (35) has on its underside, that is to say, on the side of the support plate (19), a stop (81) or retaining means, come from the molding, and located in the vicinity of the base of the petal (35).
  • This stop (81) is intended to retain the ball (34) towards the crown (80), when the corresponding receptacle (23) receives a casing to be centrifuged, during the centrifugation phases.
  • Each of the petals (35) is subjected to a stress transmitted via the lug (36) when a receptacle (23) receives a centrifuge box, because the plate (21) is made of a plastic material flexible with elastic memory, and that the molding gives it a shape such that it naturally tends to cause the cooperation of the lug (36), with the slot (25), upwards.
  • any lowering of the lug (36) causes the concomitant lowering of the stopper (81) for retaining balls (34).
  • the two extreme positions of the plate (21) are visible respectively in FIGS. 10 and 11.
  • the casings (50) when it is desired to centrifuge the casings (50), the latter are positioned within the receptacles (23), by means of the positioning pins (31), and the various centrifugation phases can be immediately carried out, without worry about balancing the device.
  • the mass of the housings (50) to be centrifuged being known
  • the mass of the balancing balls (34) is adapted, using balls of known diameter (the density of the balls remaining constant, the only parameter being able to vary the mass is the diameter), so that the sum of the moments, relative to the axis of the motor (13), of the centrifugal forces applying on the balls (34) in the low position and on the housing (50 ) to be centrifuged correspondingly, ie equal to the moments with respect to the same axis of the centrifugal forces applying to the balls in the high position of the same pair of ramps (33).
  • the empty receptacles do not cause the petals (35) of the plate (21) to be lowered, therefore do not prevent the balls from rising to the top of the corresponding ramps.
  • the larger the radius of the circle described by the object on which said forces are based, and the greater its moment relative to the axis passing through the center of said circle it is possible, by calculating beforehand the mass of the balls (34) necessary for balancing, to obtain dynamic and automatic balancing.
  • each petal (35) is articulated individually on an axis (83), orthogonal to the axis of rotation, and journalled on the locking plate (21). Under these conditions, the low rest position of a petal (35) is in contact with a ball (34).
  • a corresponding housing (50) is present on the upper plate (22)
  • the corresponding ball (34) cannot go up towards the high end of the corresponding ramp (33) being blocked by the stop (81);
  • the stop (36) is not blocked from above, and the ball (34) pushes the stop (81), and therefore the corresponding petal (35), and can reach the 'high end of the ramp (33).
  • This particular embodiment avoids exerting a rappelling push on each box (50).
  • the fixed plate (12) has in the vicinity of its periphery and over a given sector a portion called “pivoting portion” (37).
  • This pivoting portion (37) has two guide rails (38) and (39), concentric and orthogonal to the plane of the fixed plate (12).
  • the pivoting portion (37) coplanar with said fixed plate (12) integrates with this plate and defines a flange or peripheral guide (17) complete, that is to say - say defining a perfect circle.
  • the pivoting device also has an electromagnet (40) intended to attract towards the outside of the fixed plate (12) said pivoting portion (37), which is articulated at one of its ends to pivot in the plane.
  • each pivot axis (30) mentioned above has at its lower end a pin (41) intended to cooperate with a mortise (42) formed on a rod (43) disposed parallel to the fixed plate (12); each link (43) acts as a link between two coplanar and identical rollers (44) and (45), the pivot axis of which is parallel to the axis (30).
  • These rollers (44) and (45), disposed respectively at the two ends of a link (43), bear when the plates (19, 21 and 22) are in rotation on the peripheral rim (17) of the fixed plate ( 12).
  • the rollers (44) and (45) of each pivoting member are rotated by means of the axis (30), the latter being itself driven by means of the orifices (32) formed on the support plate (19).
  • the rails (38,39) are spaced apart by a distance corresponding to the diameter of the rollers (44,45).
  • the radius of curvature of the outer guide rail (39) has the same value as that of the peripheral edge (17) of the fixed plate (12), and this in order to provide a complete peripheral edge when it is not desired to carry out a pivoting phase.
  • the length of the internal guide rail (38) is shorter than the external guide rail (39), and this by a value corresponding to the diameter of the rollers (44,45), with variations in circumference , because the radii of the circles on which the rails (38,39) are based do not have the same value, as can be seen more clearly in Figure 7.
  • the edge (46) is connected to the peripheral rim (17) of said plate (12), and it constitutes, in fact, a simple extension of said rim (17) outside the fixed plate (12). Therefore, it has the same thickness and the same height as this rim (17).
  • the free end of the edge (46) coincides with one of the ends of the external guide rail (39), that opposite to the pivot axis (47) of the pivoting portion (37), when said pivoting portion is actuated.
  • the free end of the connecting edge (46) has a circular curvature whose radius is equal to the radius of the rollers (44,45), to the different thicknesses.
  • the device comprises means capable of causing the pivoting portion (37) to pivot.
  • this means is an electromagnet (40), fixed on the fixed plate (12).
  • This electromagnet is advantageously controlled by means of a microcomputer, in order to synchronize in a simple and rapid manner the pivoting or non-pivoting of the different rotary axes (30) that the device comprises.
  • a magnetic core (83) slides conventionally in the body of the electromagnet (40), and is fixed at one of its ends to a fixing lug (84) located on the pivoting portion (8) .
  • the device comprises a spiral spring in tension (85), the points of application of which are respectively located on a lug (88), fixed at the free end of the connection edge (46), and on a lug (87), fixed in the vicinity from the end of the pivoting portion (37) located towards the pivot axis (47).
  • FIGS 8 and 9 illustrate clearly the mode of action of the device according to the invention.
  • the pivoting portion (37) when the electromagnet is not activated, defines a peripheral circular rim (17) complete with the plate (12), and when said electromagnet (40) is activated, then allows, as it will be now described, the pivoting of the axis (30) considered.
  • each of the two rollers (44,45) of the axes (30) are in contact with the peripheral circular rim complete (17) of the plate (12), due to the fact that the axis (30) follows a constant circular trajectory imposed by the rotating plate (19), this trajectory being located in the vicinity of said flange, in order to involve the contact of said rollers (44,45) with the flange (17).
  • the link (43), connecting the two rollers (44,45) to the axis (30) being rigid, it imposes, due to the trajectory of the axis (30), the contact of the two rollers with the rim (17).
  • the electromagnet (40) When one wishes to cause the pivoting of one hundred and eighty degrees (180 °) of one or more mobiles (30), the electromagnet (40) is actuated which attracts the pivoting portion (37) towards it, by rotation of the latter around its own pivot axis (47).
  • the front roller (45) due to the rotation of the axis or axes (30), engages in the guide track defined by the two rails (38,39).
  • the pivoting portion (37) Because the pivoting portion (37) is in a position spaced from its original position, the roller (45) itself deviates from its circular path, causing a separation of the rear roller (44) from the flange (17 ), and this towards the inside of the fixed plate (12), due to the constant circular trajectory of the axis (30) and the rigidity of the link (43).
  • the trajectory of the rear roller (44) is imposed by the rotation of the link (43) around the pivot axis (30), rotation itself imposed by the path followed by the front roller (45).
  • roller (44) continues its own trajectory inside the plate (12) and joins the circular peripheral rim (17) in front of the roller (45), which has completed its stroke in the pivoting portion (37).
  • the turntable (19) must rotate anticlockwise (that is to say counterclockwise), so that the front roller ( 45) of each of the axes (30) penetrates the correct side of the pivoting portion (37).
  • the analysis boxes (50) comprise in a known manner a chamber for the reagent, a chamber for the reagent and a reading cell (82) having at least two parallel faces. They are secured to each individual support (27) by means of positioning lugs (31). They undergo a pivoting of 180 °, by means of the pivoting axis (30), in order to allow the inversion of the centrifugal force which is exerted on them, said centrifugal force being intended to transfer liquids, due to the use of capillaries to connect the different chambers within this housing (50). It should be noted that each of the boxes (50) has on one of the side surfaces a code / bar carrying the analysis parameter used and the expiration date of said box.
  • optical system allowing, in addition to reading the code / bar, spectrophotometric analysis by absorbance of the result of the reaction between the reagent and the reagent present in said housing (50).
  • This optical system (see FIG. 5) comprises a lamp (51) fixed on a swivel plate (52) at 90 °, in order to facilitate the lamp changing phases via the hatch (11).
  • the lamp (51) is surmounted by a spherical mirror (53) intended to focus at the level of a first diaphragm (54) the light beam which it receives.
  • the diaphragm (54) is followed by a lens (55) intended to form a parallel beam of light from the diaphragm (54).
  • This parallel beam is then calibrated by means of a second diaphragm (56), and sent through the reading cell (83) of the boxes (50).
  • the optical system is constructed in such a way that it frees up a space corresponding to the thickness of the housing (50).
  • the light beam transmitted by the reading cells of the housings (50) is focused by means of a converging lens (57) on the end of a single-strand optical fiber (58) made of silica, intended to transmit the light beam up to to the optical analysis system.
  • This code / bar reading cell (59) is connected to an electronic card decrypting the code / bar and the parameter used in the boxes and the expiration date. This first part of the optical system is detailed in FIG. 5.
  • a cell (62) makes it possible to carry out a measurement at zero order of the total light, in order to monitor the variations of the lamp (51). Simultaneously, the intensity of certain lines of the order -1 is analyzed by means of a strip of photodiodes (63), practically facing the holographic network (61). The characteristics of the photodiodes are predetermined.
  • the assembly constituted by the holographic network (61), the arrays of photodiodes (63) and the second optical assembly are inserted within the housing (64), protected from light and dust.
  • the connections from the photodiodes (63) are connected to electronic cards in a conventional manner, and then interpreted by means of a microcomputer previously mentioned.
  • the thermostat member illustrated in FIG. 4, firstly comprises a fan (70) pulsating air through heating resistors (71), at the end of which the pulsed air is guided through the by means of a heat flow guide (72), on the centrifuge device.
  • the upper plate of the latter has in its center a dome (73), intended to distribute the heat flow over all of the housings (50). Due to the presence of the cover (3) and the sealing member (6), the hot air is recycled, and re-aspirated via a channel (74) located under the fan (70).
  • the whole device is governed by a microcomputer which orders the different phases of centrifugation, pivoting, thermostatization and optical analysis.
  • This microcomputer is controlled by means of a touch keyboard (5).

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Claims (10)

  1. Zentrifugenvorrichtung zum Durchführen von Analysen, insbesondere biologischen und medizinischen Analysen von Proben, die in einem Analysenbehälter (50) mit einer Ablesezelle (82) für absorptions-spektralphotometrische Messungen enthalten sind, wobei die Vorrichtung enthält:
    - eine von einem Motor (13) in Rotation versetzte Trägerscheibe (19), die an ihrer Peripherie eine Vielzahl von Einzelauflagern (27) für die Behälter (50) aufweist, die ihrerseits gegenüber der Trägerscheibe drehbar sind;
    - Mittel (12,30,44,45) zum Verschwenken jedes Einzelauflagers gegenüber der Trägerscheibe, zum Ausrichten der Zentrifugalkraft in bezug auf jeden Analysenbehälter;
    - eine spektralphotometrische Meßanordnung (51,52,61,4), deren Strahlengang senkrecht zur Trägerscheibe verläuft und geeignet ist, die Ablesezelle eines jeden in Rotation befindlichen Behälters in einer festgelegten Position zu durchstrahlen;
    dadurch gekennzeichnet, daß die Mittel zum Verschwenken eines jeden Einzelauflagers enthalten:
    - einen gegenüber der Trägerscheibe (19) feststehenden Teller (12), der unterhalb derselben angeordnet ist und einen Führungsrand (17) aufweist;
    - ein mit dem feststehenden Teller koplanares Schwenkteil (37), das an einem Ende (47) an demselben angelenkt ist und mindestens eine Führungsschiene (38,39) aufweist, mit einem Krümmungsradius, der mit dem des Führungsrandes (17) des feststehenden Tellers übereinstimmt, wobei das Schwenkteil zwischen zwei Stellungen bewegbar ist,einer ersten Stellung, in der die Führungsschiene mit dem Führungsrand des feststehenden Tellers übereinstimmt, und einer zweiten Stellung, in der die Führungsschiene mit dem freien Ende eines Anschlusses (46) übereinstimmt, der aus dem feststehenden Teller nach außen vorspringt und mit dem Führungsrand verbunden ist;
    - eine Vielzahl zur Trägerscheibe (19) rechtwinkliger, auf derselben frei drehbar angeordneter Achsbolzen (30), an deren oberem Ende die verschiedenen Einzelauflager (27) befestigt sind und an deren unterem Ende verschiedene, zum feststehenden Teller Parallele Schwingarme (43) befestigt sind, wobei jeder Schwingarm an seinen beiden Enden zwei koplanare, sich an dem Führungsrand des feststehenden Tellers abstützende Rollen (44,45) aufweist;
    - Mittel (40) zur Betätigung des Schwenkteils (37).
  2. Vorrichtung nach Anspruch 1, dadurch gekennzeichnet, daß die Krümmung des freien Endes des nach außen vorspringenden Anschlusses (46) gleich der Krümmung der Rollen (44,45) ist.
  3. Vorrichtung nach Anspruch 1, dadurch gekennzeichnet, daß Mittel zum dynamischen Auswuchten auf der Trägerscheibe angeordnet sind und umfassen:
    - auf der Trägerscheibe (19) eine Vielzahl von radialen Rampen (33), die den verschiedenen Einzelauflagern (27) zugeordnet sind, wobei jede radiale Rampe von der Mitte in Richtung zur Peripherie der Trägerscheibe ansteigt, sowie eine Vielzahl von Auswuchtkugeln (34), welche jeweils von den verschiedenen radialen Rampen (33) aufgenommen sind;
    - eine parallel zur Trägerscheibe angeordnete, mit dieser in Rotation fest verbundene Verriegelungsplatte (21), die eine Vielzahl radialer Elemente (35) aufweist, von denen jedes um eine zur Drehachse senkrechte Achse bewegbar ist, wobei jedes radiale Element auf der der Trägerscheibe (19) abgewandten Seite einen gegen einen Analysenbehälter anlegbaren Anschlag (36) und auf der der Trägerscheibe (19) zugewandten Seite, in Nähe des Drehpunktes derselben, ein Rückhaltemittel (81) für eine korrespondierende Auswuchtkugel aufweist.
  4. Vorrichtung nach Anspruch 3, dadurch gekennzeichnet, daß jedes Einzelauflager (27) mit einem Paar ansteigender Rampen (33) und Auswuchtkugeln (34) auf der Trägerscheibe korrespondiert.
  5. Vorrichtung nach Anspruch 4, dadurch gekennzeichnet, daß die ein Paar bildenden Rampen (33) zu beiden Seiten eines Auges (32) angeordnet sind, das für die Verschwenkung des Achsbolzens (30) eines Einzelauflagers (27) vorgesehen ist.
  6. Vorrichtung nach Anspruch 3, dadurch gekennzeichnet, daß die ansteigenden radialen Rampen (33) eine Neigung gegenüber der Horizontalen aufweisen, die zwischen zehn (10) und fünfzehn Grad, vorzugsweise in der Nähe von zwölf Grad liegt.
  7. Vorrichtung nach Anspruch 3, dadurch gekennzeichnet, daß die Verriegelungsplatte (21) die Form einer Blütenkrone hat, deren Blütenblätter (35) mit den radialen Elementen zusammenfallen.
  8. Vorrichtung nach Anspruch 1, dadurch gekennzeichnet, daß sie eine obere Platte (22) aufweist, die mit der Trägerscheibe (19) in Rotation fest verbunden und parallel oberhalb derselben angeordnet ist, und die zu ihrem Umfang hin eine Vielzahl von Aufnahmen (23) für die verschiedenen Behälter (50) aufweist, wobei eine Öffnung (26) für den Durchgang des Achsbolzens (30) zum Verschwenken jedes Einzelauflagers (27) in jeder Aufnahme (23) ausgespart ist.
  9. Vorrichtung nach den Ansprüchen 3 und 8, dadurch gekennzeichnet, daß einerseits die Verriegelungsplatte (21) zwischen der Trägerscheibe (19) und der oberen Platte (22) angeordnet ist und andererseits die verschiedenen Anschläge (36) in oberer Position durch den verschiedenen Aufnahmen zugeordnete Schlitze (25) hindurchgreifen.
  10. Vorrichtung nach Anspruch 1, dadurch gekennzeichnet, daß die Trägerscheibe (19) mit einem Positionszeiger (48) versehen ist, der eine Ortsbestimmung des Analysenbehälters (50) ermöglicht.
EP87420250A 1986-09-25 1987-09-24 Zentrifugenvorrichtung zum Durchführen von Analysen Expired - Lifetime EP0262060B1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
FR8613550 1986-09-25
FR8613552A FR2605104B1 (fr) 1986-09-25 1986-09-25 Dispositif d'equilibrage dynamique d'un appareil centrifugeur
FR8613550A FR2604925B1 (fr) 1986-09-25 1986-09-25 Dispositif pour assurer le pivotement d'un mobile rotatif en deplacement sur le rebord d'un plateau
FR8613551A FR2605108B1 (fr) 1986-09-25 1986-09-25 Dispositif automatique pour la realisation d'analyses notamment biologiques et medicales
FR8613551 1986-09-25
FR8613552 1986-09-25

Publications (3)

Publication Number Publication Date
EP0262060A2 EP0262060A2 (de) 1988-03-30
EP0262060A3 EP0262060A3 (en) 1989-03-08
EP0262060B1 true EP0262060B1 (de) 1991-09-04

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EP87420250A Expired - Lifetime EP0262060B1 (de) 1986-09-25 1987-09-24 Zentrifugenvorrichtung zum Durchführen von Analysen

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EP0262060A2 (de) 1988-03-30
DE3772690D1 (de) 1991-10-10
EP0262060A3 (en) 1989-03-08
US4865810A (en) 1989-09-12

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