EP0210021A3 - Carbonic anhydrase inhibitor-tagged nucleic acid probes - Google Patents
Carbonic anhydrase inhibitor-tagged nucleic acid probes Download PDFInfo
- Publication number
- EP0210021A3 EP0210021A3 EP86305300A EP86305300A EP0210021A3 EP 0210021 A3 EP0210021 A3 EP 0210021A3 EP 86305300 A EP86305300 A EP 86305300A EP 86305300 A EP86305300 A EP 86305300A EP 0210021 A3 EP0210021 A3 EP 0210021A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- carbonic anhydrase
- nucleic acid
- methods
- probes
- reporter group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 102000003846 Carbonic anhydrases Human genes 0.000 title abstract 4
- 108090000209 Carbonic anhydrases Proteins 0.000 title abstract 4
- 108020004711 Nucleic Acid Probes Proteins 0.000 title 1
- 239000002853 nucleic acid probe Substances 0.000 title 1
- 239000000523 sample Substances 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 4
- 125000006853 reporter group Chemical group 0.000 abstract 3
- 101001091385 Homo sapiens Kallikrein-6 Proteins 0.000 abstract 2
- 102100034866 Kallikrein-6 Human genes 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- -1 nucleotide phosph ates Chemical group 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 229920001519 homopolymer Polymers 0.000 abstract 1
- 238000009396 hybridization Methods 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000007899 nucleic acid hybridization Methods 0.000 abstract 1
- 239000002777 nucleoside Substances 0.000 abstract 1
- 150000003833 nucleoside derivatives Chemical class 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 229940124530 sulfonamide Drugs 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/753,176 US4780405A (en) | 1985-06-25 | 1985-07-09 | Carbonic anhydrase inhibitor-tagged nucleic acid probes |
US753176 | 2004-01-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0210021A2 EP0210021A2 (en) | 1987-01-28 |
EP0210021A3 true EP0210021A3 (en) | 1987-09-02 |
Family
ID=25029490
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP86305300A Withdrawn EP0210021A3 (en) | 1985-07-09 | 1986-07-09 | Carbonic anhydrase inhibitor-tagged nucleic acid probes |
Country Status (4)
Country | Link |
---|---|
US (1) | US4780405A (en) |
EP (1) | EP0210021A3 (en) |
JP (1) | JPS6214800A (en) |
CA (1) | CA1294899C (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4948882A (en) * | 1983-02-22 | 1990-08-14 | Syngene, Inc. | Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis |
US5210203A (en) * | 1985-06-25 | 1993-05-11 | Siska Diagnostics, Inc. | Sulfonamide-derivative compounds for tagging nucleic acid probes |
US5093232A (en) * | 1985-12-11 | 1992-03-03 | Chiron Corporation | Nucleic acid probes |
GB2209754A (en) * | 1987-09-17 | 1989-05-24 | Thomas Lee Mattson | Polyaldehydic polynucleotides in use as probes,their preparation and use |
US5210015A (en) * | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
US6277569B1 (en) | 1990-09-20 | 2001-08-21 | Vysis, Inc. | Methods for multiple direct label probe detection of multiple chromosomes or regions thereof by in situ hybridization |
US5491224A (en) * | 1990-09-20 | 1996-02-13 | Bittner; Michael L. | Direct label transaminated DNA probe compositions for chromosome identification and methods for their manufacture |
US20060078914A1 (en) * | 1993-01-05 | 2006-04-13 | Gelfand David H | Homogeneous assay system |
JPH0737397Y2 (en) * | 1993-08-03 | 1995-08-23 | コルチトーン補聴器株式会社 | Hearing aid telephone listening device |
US6048688A (en) * | 1996-11-12 | 2000-04-11 | Kimberly-Clark Corporation | Method for detection of Pseudomonas aeruginosa using polymerase chain reaction |
US6956695B2 (en) * | 2001-03-19 | 2005-10-18 | Ikonisys, Inc. | System and method for increasing the contrast of an image produced by an epifluorescence microscope |
US8709721B2 (en) | 2009-10-01 | 2014-04-29 | Riken | Fluorescent molecule and method for detecting target nucleic acid |
WO2018218250A2 (en) * | 2017-05-26 | 2018-11-29 | Vibrant Holdings, Llc | Photoactive compounds and methods for biomolecule detection and sequencing |
CN107417681B (en) * | 2017-06-15 | 2020-01-17 | 安徽大学 | Fluorescent probe compound containing coumarin-thiadiazole Schiff base and preparation method and application thereof |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2407686A (en) * | 1943-04-21 | 1946-09-17 | Frances R Ruskin | Sulphanilamide derivatives and method of preparing same |
FR992364A (en) * | 1944-06-22 | 1951-10-17 | Prod De Chimie Organique De La | Process for the preparation of water soluble sulfanilamides |
GB844946A (en) * | 1957-03-14 | 1960-08-17 | American Cyanamid Co | New 2-(n-substituted)-acylamino-1,3,4-thiadiazole-5-sulfonamides |
US4255182A (en) * | 1980-03-10 | 1981-03-10 | Velsicol Chemical Corporation | Aminosulfonylthiadiazolylureas |
EP0063879A2 (en) * | 1981-04-17 | 1982-11-03 | Yale University | Modified nucleotides and methods of preparing and using same |
WO1984003285A1 (en) * | 1983-02-22 | 1984-08-30 | Molecular Biosystems Inc | Defined sequence single strand oligonucleotides incorporating reporter groups, process for the chemical synthesis thereof, and nucleosides useful in such synthesis |
EP0097373B1 (en) * | 1982-06-23 | 1992-10-07 | Enzo Biochem, Inc. | Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4134792A (en) * | 1976-12-06 | 1979-01-16 | Miles Laboratories, Inc. | Specific binding assay with an enzyme modulator as a labeling substance |
-
1985
- 1985-07-09 US US06/753,176 patent/US4780405A/en not_active Expired - Fee Related
-
1986
- 1986-06-04 CA CA000510835A patent/CA1294899C/en not_active Expired - Fee Related
- 1986-07-09 EP EP86305300A patent/EP0210021A3/en not_active Withdrawn
- 1986-07-09 JP JP61161756A patent/JPS6214800A/en active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2407686A (en) * | 1943-04-21 | 1946-09-17 | Frances R Ruskin | Sulphanilamide derivatives and method of preparing same |
FR992364A (en) * | 1944-06-22 | 1951-10-17 | Prod De Chimie Organique De La | Process for the preparation of water soluble sulfanilamides |
GB844946A (en) * | 1957-03-14 | 1960-08-17 | American Cyanamid Co | New 2-(n-substituted)-acylamino-1,3,4-thiadiazole-5-sulfonamides |
US4255182A (en) * | 1980-03-10 | 1981-03-10 | Velsicol Chemical Corporation | Aminosulfonylthiadiazolylureas |
EP0063879A2 (en) * | 1981-04-17 | 1982-11-03 | Yale University | Modified nucleotides and methods of preparing and using same |
EP0097373B1 (en) * | 1982-06-23 | 1992-10-07 | Enzo Biochem, Inc. | Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same |
WO1984003285A1 (en) * | 1983-02-22 | 1984-08-30 | Molecular Biosystems Inc | Defined sequence single strand oligonucleotides incorporating reporter groups, process for the chemical synthesis thereof, and nucleosides useful in such synthesis |
Non-Patent Citations (2)
Title |
---|
CHEMICAL ABSTRACS, vol. 78, no. 13, 2nd April 1973, page 351, column 2, abstract no. 83315r, Columbus, Ohio, US; H. GOYA et al.: "Sulfanilamides as inhibitors of oxidations of ammoniacal nitrogen in soils "; & JP-A-47 004 966 (YOSHITOMI PHARMACEUTICAL IND.,LTD). * |
CHEMICAL ABSTRACTS, vol. 98, no. 5, 31th January 1983, page 297, column 1, abstract no. 30198m, Columbus, Ohio, US: J.N. SHEPARD et al. "The measurement of human erythrocyte carbonic anhydrase I by the enzyme-linked immunosorbent assay (ELISA)"; & CLIN. BIOCHEM. (OTTAWA), vol. 15, no. 5, 1982, 248-251. * |
Also Published As
Publication number | Publication date |
---|---|
EP0210021A2 (en) | 1987-01-28 |
JPS6214800A (en) | 1987-01-23 |
CA1294899C (en) | 1992-01-28 |
US4780405A (en) | 1988-10-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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AK | Designated contracting states |
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17P | Request for examination filed |
Effective date: 19880226 |
|
17Q | First examination report despatched |
Effective date: 19900514 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 19901127 |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: MUSSO, GARY FRED Inventor name: GHOSH, SOUMITRA SHANKAR Inventor name: WAHL, GEOFFREY MYLES Inventor name: KAISER, EMIL THOMAS Inventor name: ORGEL, LESLIE ELEAZER |