EP0165307A4 - Synthetic polypeptide corresponding to a portion of the heat-labile enterotoxin of escherichia coli, compositions and methods therewith. - Google Patents

Synthetic polypeptide corresponding to a portion of the heat-labile enterotoxin of escherichia coli, compositions and methods therewith.

Info

Publication number
EP0165307A4
EP0165307A4 EP19850900404 EP85900404A EP0165307A4 EP 0165307 A4 EP0165307 A4 EP 0165307A4 EP 19850900404 EP19850900404 EP 19850900404 EP 85900404 A EP85900404 A EP 85900404A EP 0165307 A4 EP0165307 A4 EP 0165307A4
Authority
EP
European Patent Office
Prior art keywords
compositions
heat
escherichia coli
synthetic polypeptide
polypeptide corresponding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19850900404
Other languages
German (de)
French (fr)
Other versions
EP0165307A1 (en
Inventor
Richard A Houghten
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Clinic and Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic and Research Foundation filed Critical Scripps Clinic and Research Foundation
Publication of EP0165307A1 publication Critical patent/EP0165307A1/en
Publication of EP0165307A4 publication Critical patent/EP0165307A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1228—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K16/1232—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia from Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Medicinal Preparation (AREA)
EP19850900404 1983-12-12 1984-12-12 Synthetic polypeptide corresponding to a portion of the heat-labile enterotoxin of escherichia coli, compositions and methods therewith. Withdrawn EP0165307A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55946983A 1983-12-12 1983-12-12
US559469 2006-11-14

Publications (2)

Publication Number Publication Date
EP0165307A1 EP0165307A1 (en) 1985-12-27
EP0165307A4 true EP0165307A4 (en) 1989-06-14

Family

ID=24233715

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19850900404 Withdrawn EP0165307A4 (en) 1983-12-12 1984-12-12 Synthetic polypeptide corresponding to a portion of the heat-labile enterotoxin of escherichia coli, compositions and methods therewith.

Country Status (9)

Country Link
EP (1) EP0165307A4 (en)
JP (1) JPS61500664A (en)
KR (2) KR850005401A (en)
AU (1) AU3747185A (en)
DK (1) DK364685D0 (en)
FI (1) FI853082L (en)
NO (1) NO853153L (en)
WO (1) WO1985002611A1 (en)
ZA (1) ZA839512B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4886663A (en) * 1983-01-03 1989-12-12 Scripps Clinic And Research Foundation Synthetic heat-stable enterotoxin polypeptide of Escherichia coli and multimers thereof
US4617265A (en) * 1984-09-19 1986-10-14 Board Of Regents, University Of Texas System Colony blot assay for enterotoxigenic bacteria
US7097839B1 (en) 1993-10-26 2006-08-29 Thomas Jefferson University ST receptor binding compounds and methods of using the same
EP1011736A2 (en) * 1997-01-29 2000-06-28 Nycomed Imaging As Polymers
US7135333B1 (en) 1997-08-07 2006-11-14 Thomas Jefferson University Compositions that specifically bind to colorectal cancer cells and methods of using the same
GB9819484D0 (en) * 1998-09-07 1998-10-28 Univ Bristol Therapeutic agents
EP2949762B1 (en) 2000-03-27 2018-05-09 Thomas Jefferson University Compositions for treating stomachal and oesophageal cancer cells
WO2010027473A2 (en) 2008-09-03 2010-03-11 Board Of Trustees Of Michigan State University Immunogenic escherichia coli heat stable enterotoxin
CN104402974B (en) * 2014-12-10 2017-11-14 重庆医科大学 A kind of polypeptide with mucosal adjuvant activity and its purposes in mucosal adjuvant is prepared

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237115A (en) * 1977-11-23 1980-12-02 Bactex, Inc. Method of immunization against enterotoxogenic infection by Escherichia coli
US4314993A (en) * 1980-04-04 1982-02-09 Smithkline-Rit Immunogenic E. coli ST enterotoxin derivatives and compositions containing them
US4411888A (en) * 1981-06-22 1983-10-25 The University Of Rochester Composition of a novel immunogen for protection against diarrheal disease caused by enterotoxigenic Escherichia coli
US4465665A (en) * 1982-03-04 1984-08-14 Smithkline-Rit Detoxified E. coli neurotoxin, preparation thereof and immunological preparations containing it

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
No relevant documents have been disclosed. *

Also Published As

Publication number Publication date
ZA839512B (en) 1984-08-29
AU3747185A (en) 1985-06-26
EP0165307A1 (en) 1985-12-27
DK364685A (en) 1985-08-09
JPS61500664A (en) 1986-04-10
DK364685D0 (en) 1985-08-09
FI853082A0 (en) 1985-08-12
KR850700134A (en) 1985-10-25
KR850005401A (en) 1985-08-24
WO1985002611A1 (en) 1985-06-20
FI853082L (en) 1985-08-12
NO853153L (en) 1985-09-13

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Designated state(s): AT BE CH DE FR GB LI LU NL SE

17P Request for examination filed

Effective date: 19851204

A4 Supplementary search report drawn up and despatched

Effective date: 19890614

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN

18W Application withdrawn

Withdrawal date: 19890808

R18W Application withdrawn (corrected)

Effective date: 19890808

RIN1 Information on inventor provided before grant (corrected)

Inventor name: HOUGHTEN, RICHARD, A.