EP0153113A3 - Thermospray ion sampling device - Google Patents

Thermospray ion sampling device Download PDF

Info

Publication number
EP0153113A3
EP0153113A3 EP85300876A EP85300876A EP0153113A3 EP 0153113 A3 EP0153113 A3 EP 0153113A3 EP 85300876 A EP85300876 A EP 85300876A EP 85300876 A EP85300876 A EP 85300876A EP 0153113 A3 EP0153113 A3 EP 0153113A3
Authority
EP
European Patent Office
Prior art keywords
thermospray
sampling device
mass
ions
thermospray ion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP85300876A
Other languages
German (de)
French (fr)
Other versions
EP0153113A2 (en
Inventor
William H. Mcfadden
Michael G. Tucker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thermo Finnigan LLC
Original Assignee
Finnigan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Finnigan Corp filed Critical Finnigan Corp
Publication of EP0153113A2 publication Critical patent/EP0153113A2/en
Publication of EP0153113A3 publication Critical patent/EP0153113A3/en
Ceased legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0468—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components with means for heating or cooling the sample
    • H01J49/049—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components with means for heating or cooling the sample with means for applying heat to desorb the sample; Evaporation
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • H01J49/0445—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples with means for introducing as a spray, a jet or an aerosol
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • H01J49/067—Ion lenses, apertures, skimmers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)

Abstract

The performance of a thermospray ion source for liquid chromatograph/mass spectrometers is improved dramatically by providing a voltage gradient across the thermospray jet stream to increase the efficiency of transferring ions of all masses from the thermospray jet stream to the mass spectrom­ eter, and in particular the intensity of high mass ions relative to low mass ions.
EP85300876A 1984-02-10 1985-02-08 Thermospray ion sampling device Ceased EP0153113A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57921184A 1984-02-10 1984-02-10
US579211 1990-09-05

Publications (2)

Publication Number Publication Date
EP0153113A2 EP0153113A2 (en) 1985-08-28
EP0153113A3 true EP0153113A3 (en) 1987-09-23

Family

ID=24316012

Family Applications (1)

Application Number Title Priority Date Filing Date
EP85300876A Ceased EP0153113A3 (en) 1984-02-10 1985-02-08 Thermospray ion sampling device

Country Status (2)

Country Link
EP (1) EP0153113A3 (en)
JP (1) JPS60237354A (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861989A (en) * 1983-08-30 1989-08-29 Research Corporation Technologies, Inc. Ion vapor source for mass spectrometry of liquids
US4814612A (en) * 1983-08-30 1989-03-21 Research Corporation Method and means for vaporizing liquids for detection or analysis
US4730111A (en) * 1983-08-30 1988-03-08 Research Corporation Ion vapor source for mass spectrometry of liquids
GB8404683D0 (en) * 1984-02-22 1984-03-28 Vg Instr Group Mass spectrometers
GB2324906B (en) 1997-04-29 2002-01-09 Masslab Ltd Ion source for a mass analyser and method of providing a source of ions for analysis
JP3694598B2 (en) * 1998-10-14 2005-09-14 株式会社日立製作所 Atmospheric pressure ionization mass spectrometer
AU2003263537A1 (en) * 2002-10-10 2004-05-04 Universita' Degli Studi Di Milano Ionization source for mass spectrometry analysis

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4160161A (en) * 1978-05-30 1979-07-03 Phillips Petroleum Company Liquid chromatograph/mass spectrometer interface

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5291497A (en) * 1976-01-27 1977-08-01 Kankiyou Rikagaku Kenkiyuushiy Measuring apparatus for vinyl chloride monomer concentration

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4160161A (en) * 1978-05-30 1979-07-03 Phillips Petroleum Company Liquid chromatograph/mass spectrometer interface

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ANALYTICAL CHEMISTRY, vol. 55, no. 11, September 1983, pages 1741-1744, American Chemical Society, Washington, DC., US; D.J. LIBERATO et al.: "Charaterization of glucuronides with a thermospray liquid chromatography/mass spectrometry interface" *

Also Published As

Publication number Publication date
EP0153113A2 (en) 1985-08-28
JPS60237354A (en) 1985-11-26

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18R Application refused

Effective date: 19900302

RIN1 Information on inventor provided before grant (corrected)

Inventor name: MCFADDEN, WILLIAM H.

Inventor name: TUCKER, MICHAEL G.