EP0126642A2 - Transfer device for the interconnection of single-use synthetic bags and/or systems for therapeutic or other purposes - Google Patents

Transfer device for the interconnection of single-use synthetic bags and/or systems for therapeutic or other purposes Download PDF

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Publication number
EP0126642A2
EP0126642A2 EP19840303400 EP84303400A EP0126642A2 EP 0126642 A2 EP0126642 A2 EP 0126642A2 EP 19840303400 EP19840303400 EP 19840303400 EP 84303400 A EP84303400 A EP 84303400A EP 0126642 A2 EP0126642 A2 EP 0126642A2
Authority
EP
European Patent Office
Prior art keywords
tube
bag
transfer device
transfer
piercing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19840303400
Other languages
German (de)
French (fr)
Other versions
EP0126642A3 (en
Inventor
Sandorne Daroczy
Ilon Fazekas
Sandorne Hegyes
Dezsö Kardos
Marta Sipos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medicor Muvek
Original Assignee
Medicor Muvek
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicor Muvek filed Critical Medicor Muvek
Publication of EP0126642A2 publication Critical patent/EP0126642A2/en
Publication of EP0126642A3 publication Critical patent/EP0126642A3/en
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10—Bag-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/2013—Piercing means having two piercing ends

Definitions

  • the invention relates to a transfer device whereby single-use synthetic bags and/orsystems provided with independent compartments for therapeutic or other purposes can be interconnected by passing a tube through a built-in diaphragm.
  • multi-part synthetic bags are used in medical practice, particularly in case of blood-taking, blood-processing and for the production of blood preparations. These are subjected to autoclave with the appropriate solutions before use.
  • the blood-taking bag contains a blood preserving solution and the supplementary, so-called transfer, bags contain a resuspension solution.
  • the blood preparations can be produced in the multi-part bags by ensuring the transfer between the bags - containing occasionally different solutions and separated by a diaphragm from each other - with the aid of suitable devices.
  • the other known type is the needle-type device described e.g. in DE-A-2 026 086 and 2 331 687.
  • the needle-type devices produced so far are labour- intensive and owing to the multiple use of the rubber hoses the process of puncture is not visible.
  • the invention aims to eliminate or reduce the shortcomings of the existing devices, lower their production costs, facilitate assembly, obviate the need for an auxiliary device during manipulation, easy passage of the medium transferred and visibility.
  • the invention is based on the recognition that the operation of such transfer devices becomes reliable and the position is always perceptible by providing the elements of the device with suitable locking, and that by a suitable formation of the piercing tube the use of auxiliary means is eliminated.
  • the invention thus relates to a transfer device for the interconnection of multi-part synthetic bags and/or systems having independent compartments, used once only for therapeutic or other purposes, including a transfer tube extending through the wall of the synthetic bag, a sealing diaphragm arranged within the tube, a piercing tube extending from the interior of the synthetic bag, an internal flange on the wall of the transfer tube between its end at the internal space of the synthetic bag and the diaphragm, and a groove arranged on the piercing tube into which the internal flange fits in the closed position.
  • a pressure plate is arranged on the piercing tube at its end at the internal space of the synthetic bag.
  • an opening preferably a slot, is arranged on the pressure plate at the stem of the piercing tube.
  • the synthetic bags 9 and 10 shown in Figure 1 are interconnected by a tube.
  • a transfer device according to the invention is arranged in the wall of the synthetic bag 9.
  • the transfer device is shown in detail in Figure 2. It includes a transfer tube 4 which is welded into the wall 11 of the synthetic bag 9.
  • the bag 9 is closed with a diaphragm 2 at approximately the middle part of the tube 4 which has an internal flange 5 formed at its inner and, i.e. the end adjacent the interior of the synthetic bag.
  • the transfer tube 4, the diaphragm 2 and flange 5 are produced as a one-piece, soft synthetic material, by injection moulding.
  • a sharp-tipped piercing tube 1 is arranged in that part of the transfer tube 4 which is adjacent the interior of the synthetic bag 9.
  • the piercing tube 1 is produced from a hard synthetic material of suitable strength, also by injection moulding.
  • a groove or reduced section 3 is formed on the stem of the piercing tube 1 between a collar 12 and a guide cone 8. The latter is formed adjacent the tip end of the piercing tube 1 in order to facilitate the assembly.
  • a pressure plate 6 is arranged at the end opposite the tip of the piercing tube 1, and is provided with a slot 7 ( Figure 4) passing to the stem parallel with the longitudinal axis of the piercing tube 1.
  • the transfer device operates in the following manner.
  • the internal flange 5 of the transfer tube 4 engages in the groove 3 of the piercing tube 1.
  • the tip of the piercing tube 1 is spaced from the diaphragm 2 which thus closes the transfer tube 4.
  • the piercing tube 1 is pushed towards the diaphragm 2 by compressing the soft wall of the synthetic bag 9 with the aid of the pressure plate 6. This causes the internal flange 5 to snap out of the groove 3 and the tip of the piercing tube 1 can easily be passed through the diaphragm 2 until the pressure plate 6 abuts the end of the transfer tube 4, Figure 3.
  • the slot 7 in the pressure plate 6 assures a complete discharge of the contents of the synthetic bag 9.
  • the thickness of the diaphragm 2 and/or the distance of the tip of the piercing tube 1 from the diaphragm in the closed position have to be selected during the design of the transfer device in accordance with the given or desired purpose.

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

A transfer device for the interconnection of multi-part, single-use, synthetic bags (9, 10) and/or systems having independent compartments for therapeutic and other purposes includes a transfer tube (4) extendingthrough the wall (11) of the synthetic bag which is sealed by a closing diaphragm (2) in the transfer tube (4). A piercing tube (1) is arranged in the interior of the synthetic bag and extends into the transfer tube (4). An internal flange (5) is formed on the wall of the transfer tube (4) at its end adjacent the interior of the synthetic bag (9). A groove (3) on the stem of the piercing tube (1) receives the internal flange (5) in the closed position of the bag (9). The piercing tube (1) terminates in a plate (6) manually engageable from the outside to push the tip of the piercing tube (1) through the diaphragm (2), whereby to allow the contents of the bag (9) to be discharged via the tubes (1) and (4).

Description

  • The invention relates to a transfer device whereby single-use synthetic bags and/orsystems provided with independent compartments for therapeutic or other purposes can be interconnected by passing a tube through a built-in diaphragm.
  • As is known, multi-part synthetic bags are used in medical practice, particularly in case of blood-taking, blood-processing and for the production of blood preparations. These are subjected to autoclave with the appropriate solutions before use. The blood-taking bag contains a blood preserving solution and the supplementary, so-called transfer, bags contain a resuspension solution. The blood preparations can be produced in the multi-part bags by ensuring the transfer between the bags - containing occasionally different solutions and separated by a diaphragm from each other - with the aid of suitable devices.
  • Two types of these devices are known; one of them is the ball or plug-type device,e.g. described in US-A-3 921 634. An external aid means is required for the opening of these devices.
  • The other known type is the needle-type device described e.g. in DE-A-2 026 086 and 2 331 687. The needle-type devices produced so far are labour- intensive and owing to the multiple use of the rubber hoses the process of puncture is not visible.
  • The invention aims to eliminate or reduce the shortcomings of the existing devices, lower their production costs, facilitate assembly, obviate the need for an auxiliary device during manipulation, easy passage of the medium transferred and visibility.
  • The invention is based on the recognition that the operation of such transfer devices becomes reliable and the position is always perceptible by providing the elements of the device with suitable locking, and that by a suitable formation of the piercing tube the use of auxiliary means is eliminated.
  • The invention thus relates to a transfer device for the interconnection of multi-part synthetic bags and/or systems having independent compartments, used once only for therapeutic or other purposes, including a transfer tube extending through the wall of the synthetic bag, a sealing diaphragm arranged within the tube, a piercing tube extending from the interior of the synthetic bag, an internal flange on the wall of the transfer tube between its end at the internal space of the synthetic bag and the diaphragm, and a groove arranged on the piercing tube into which the internal flange fits in the closed position.
  • In a preferred construction of the transfer device according to the invention, a pressure plate is arranged on the piercing tube at its end at the internal space of the synthetic bag.
  • In another preferred construction of the transfer device according to the invention an opening, preferably a slot, is arranged on the pressure plate at the stem of the piercing tube.
  • A preferred embodiment of the invention is described in detail with the aid of the accompanying drawing, in which:
    • Figure 1 is a schematic elevation showing the two synthetic bags, each having independent compartments, by means of a transfer device according to the invention,
    • Figures 2 and 3 are respectively longitudinal sections of the transfer device on an enlarged scape in the open and dosed positions, and
    • Figure 4 is a cross-section of the piercing tube, taken on the line A-A of Figure 2.
  • The synthetic bags 9 and 10 shown in Figure 1 are interconnected by a tube. A transfer device according to the invention is arranged in the wall of the synthetic bag 9.
  • The transfer device is shown in detail in Figure 2. It includes a transfer tube 4 which is welded into the wall 11 of the synthetic bag 9. The bag 9 is closed with a diaphragm 2 at approximately the middle part of the tube 4 which has an internal flange 5 formed at its inner and, i.e. the end adjacent the interior of the synthetic bag.
  • The transfer tube 4, the diaphragm 2 and flange 5 are produced as a one-piece, soft synthetic material, by injection moulding.
  • A sharp-tipped piercing tube 1 is arranged in that part of the transfer tube 4 which is adjacent the interior of the synthetic bag 9. The piercing tube 1 is produced from a hard synthetic material of suitable strength, also by injection moulding. A groove or reduced section 3 is formed on the stem of the piercing tube 1 between a collar 12 and a guide cone 8. The latter is formed adjacent the tip end of the piercing tube 1 in order to facilitate the assembly. A pressure plate 6 is arranged at the end opposite the tip of the piercing tube 1, and is provided with a slot 7 (Figure 4) passing to the stem parallel with the longitudinal axis of the piercing tube 1.
  • The transfer device operates in the following manner.
  • In the closed position the internal flange 5 of the transfer tube 4 engages in the groove 3 of the piercing tube 1. In this position, the tip of the piercing tube 1 is spaced from the diaphragm 2 which thus closes the transfer tube 4. To open the bag 9, the piercing tube 1 is pushed towards the diaphragm 2 by compressing the soft wall of the synthetic bag 9 with the aid of the pressure plate 6. This causes the internal flange 5 to snap out of the groove 3 and the tip of the piercing tube 1 can easily be passed through the diaphragm 2 until the pressure plate 6 abuts the end of the transfer tube 4, Figure 3. The slot 7 in the pressure plate 6 assures a complete discharge of the contents of the synthetic bag 9.
  • The thickness of the diaphragm 2 and/or the distance of the tip of the piercing tube 1 from the diaphragm in the closed position have to be selected during the design of the transfer device in accordance with the given or desired purpose.

Claims (5)

1. A transfer device for the interconnection of multi-part single-use bags (9, 10) and/or systems having independent compartments for therapeutic or other purposes, comprising a transfer tube (4) extending through the wall (11) of the synthetic bag (9), a bag-closing diaphragm (2) within the transfer tube (4) and a piercing tube (1), characterised in that an internal flange (5) is formed on the wall of the transfer tube (4) between its end adjacent the interior of the bag (9) and the diaphragm (2), and a groove (3) is provided on the stem of the piercing tube (1) into which the internal flange (5) engages in the closed position of the bag.
2. A transfer device as claimed in claim 1, characterised in that a pressure application plate (6) is arranged on the piercing tube (1) at its end adjacent the interior of the bag (9).
3. A transfer device as claimed in claim 1 or claim 2, characterised in that an opening (7) is arranged on the pressure application plate (6) along the stem of the piercing tube (1).
4. A transfer device as claimed in any preceding claim, characterised in that the said stem is provided with an abutment collar (12) to limit the free movement of the stem in the closed position.
5. A transfer device as claimed in any preceding claim, characterised in that the said tube (4), diaphragm (2) and flange (5) are integrally formed from a single piece of material that is softer than the material of the piercing tube (1).
EP19840303400 1983-05-18 1984-05-18 Transfer device for the interconnection of single-use synthetic bags and/or systems for therapeutic or other purposes Withdrawn EP0126642A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU174283 1983-05-18
HU831742A HU187907B (en) 1983-05-18 1983-05-18 Opening together device for connecting single-use plastic bags and/or systems of therapeutic and other purpose having self-contained spaces

Publications (2)

Publication Number Publication Date
EP0126642A2 true EP0126642A2 (en) 1984-11-28
EP0126642A3 EP0126642A3 (en) 1985-09-11

Family

ID=10955964

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19840303400 Withdrawn EP0126642A3 (en) 1983-05-18 1984-05-18 Transfer device for the interconnection of single-use synthetic bags and/or systems for therapeutic or other purposes

Country Status (2)

Country Link
EP (1) EP0126642A3 (en)
HU (1) HU187907B (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4583971A (en) * 1984-02-10 1986-04-22 Travenol European Research And Development Centre (Teradec) Closed drug delivery system
EP0205345A2 (en) * 1985-06-10 1986-12-17 Bilbate Limited Sealing cap
EP0345230A2 (en) * 1988-06-02 1989-12-06 Piero Marrucchi Method and device for manipulating and transferring products between confined volumes
US8016829B2 (en) 2004-02-09 2011-09-13 Depuy Spine, Inc. Systems and methods for spinal surgery

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2026086A1 (en) * 1969-05-28 1970-12-03 Jintan Terumo Co. Ltd., Tokio Bentel device for the transfusion of blood or fluids
US3792799A (en) * 1971-10-21 1974-02-19 Sybron Corp Method and apparatus for opening plastic containers
FR2284339A1 (en) * 1974-09-12 1976-04-09 Philips Nv INJECTOR SYRINGE CONTAINING A TELESCOPIC BETWEEN THE CARTRIDGE AND THE BULB
FR2425117A1 (en) * 1978-05-05 1979-11-30 Goglio Luigi SYRUP FEEDING SYSTEM FOR A BEVERAGE DISPENSER OF THE AFTER MIXING TYPE
US4180070A (en) * 1977-08-29 1979-12-25 Abbott Laboratories Disposable double vial syringe

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2026086A1 (en) * 1969-05-28 1970-12-03 Jintan Terumo Co. Ltd., Tokio Bentel device for the transfusion of blood or fluids
US3792799A (en) * 1971-10-21 1974-02-19 Sybron Corp Method and apparatus for opening plastic containers
FR2284339A1 (en) * 1974-09-12 1976-04-09 Philips Nv INJECTOR SYRINGE CONTAINING A TELESCOPIC BETWEEN THE CARTRIDGE AND THE BULB
US4180070A (en) * 1977-08-29 1979-12-25 Abbott Laboratories Disposable double vial syringe
FR2425117A1 (en) * 1978-05-05 1979-11-30 Goglio Luigi SYRUP FEEDING SYSTEM FOR A BEVERAGE DISPENSER OF THE AFTER MIXING TYPE

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4583971A (en) * 1984-02-10 1986-04-22 Travenol European Research And Development Centre (Teradec) Closed drug delivery system
EP0205345A2 (en) * 1985-06-10 1986-12-17 Bilbate Limited Sealing cap
EP0205345A3 (en) * 1985-06-10 1988-07-13 Bilbate Limited Sealing cap
EP0345230A2 (en) * 1988-06-02 1989-12-06 Piero Marrucchi Method and device for manipulating and transferring products between confined volumes
EP0345230A3 (en) * 1988-06-02 1990-10-31 Piero Marrucchi Method and device for manipulating and transferring products between confined volumes
US5117875A (en) * 1988-06-02 1992-06-02 Piero Marrucchi Method and device for manipulating and transferring products between confined volumes
US8016829B2 (en) 2004-02-09 2011-09-13 Depuy Spine, Inc. Systems and methods for spinal surgery
US9180024B2 (en) 2004-02-09 2015-11-10 Medos International Sarl Systems and methods for spinal surgery
US10398425B2 (en) 2004-02-09 2019-09-03 Medos International Sarl Systems and methods for spinal surgery

Also Published As

Publication number Publication date
HU187907B (en) 1986-03-28
HUT34352A (en) 1985-03-28
EP0126642A3 (en) 1985-09-11

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Effective date: 19860512

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Inventor name: SIPOS, MARTA

Inventor name: KARDOS, DEZSOE

Inventor name: FAZEKAS, ILON

Inventor name: HEGYES, SANDORNE

Inventor name: DAROCZY, SANDORNE