EP0054909A3 - 9-halo-8-hydroxy-4-methyl-4-nonenoic acids, derivatives thereof and a process for their preparation - Google Patents

9-halo-8-hydroxy-4-methyl-4-nonenoic acids, derivatives thereof and a process for their preparation Download PDF

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Publication number
EP0054909A3
EP0054909A3 EP81110514A EP81110514A EP0054909A3 EP 0054909 A3 EP0054909 A3 EP 0054909A3 EP 81110514 A EP81110514 A EP 81110514A EP 81110514 A EP81110514 A EP 81110514A EP 0054909 A3 EP0054909 A3 EP 0054909A3
Authority
EP
European Patent Office
Prior art keywords
hydroxy
methyl
halo
derivatives
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP81110514A
Other languages
German (de)
French (fr)
Other versions
EP0054909A2 (en
Inventor
Hisao Takayanagi
Yoshiharu Morita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP55179403A external-priority patent/JPS57102829A/en
Priority claimed from JP55179404A external-priority patent/JPS57102880A/en
Priority claimed from JP55180253A external-priority patent/JPS57102838A/en
Priority claimed from JP55181697A external-priority patent/JPS57106633A/en
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Publication of EP0054909A2 publication Critical patent/EP0054909A2/en
Publication of EP0054909A3 publication Critical patent/EP0054909A3/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/42—Halogenated unsaturated alcohols acyclic
    • C07C33/423—Halogenated unsaturated alcohols acyclic containing only double bonds as unsaturation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/17—Unsaturated ethers containing halogen
    • C07C43/174—Unsaturated ethers containing halogen containing six-membered aromatic rings
    • C07C43/1745—Unsaturated ethers containing halogen containing six-membered aromatic rings having more than one ether bound
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers

Abstract

9-Halo-8-hydroxy-4-methyl-4-nonenoic acids and de­ rivatives thereof have been prepared, which are impor­ tant intermediates for the full synthesis of (1RS, 4SR, 5RS)-4-(4,8-dimethyl-5-hydroxy-7-nonenyl)-4-methyl-3,8-di­ oxabicyclo[3.2.1]-octane-1-acetic acid [A]:
EP81110514A 1980-12-18 1981-12-16 9-halo-8-hydroxy-4-methyl-4-nonenoic acids, derivatives thereof and a process for their preparation Withdrawn EP0054909A3 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP179403/80 1980-12-18
JP55179403A JPS57102829A (en) 1980-12-18 1980-12-18 1-halogeno-6-methyl-5-hepten-2-ol, its derivative, and their preparation
JP55179404A JPS57102880A (en) 1980-12-18 1980-12-18 1-halogeno-5,6-epoxy-6-methyl-2-heptanol, its derivative and preparation thereof
JP179404/80 1980-12-18
JP180253/80 1980-12-19
JP55180253A JPS57102838A (en) 1980-12-19 1980-12-19 9-halogeno-8-hydroxy-4-methyl-4-nonenoic acid, its derivative and their preparation
JP55181697A JPS57106633A (en) 1980-12-22 1980-12-22 1-halogeno-5-hydroxy-6-methylene-2-heptanol, its derivative and their preparation
JP181697/80 1980-12-22

Publications (2)

Publication Number Publication Date
EP0054909A2 EP0054909A2 (en) 1982-06-30
EP0054909A3 true EP0054909A3 (en) 1982-09-01

Family

ID=27474887

Family Applications (1)

Application Number Title Priority Date Filing Date
EP81110514A Withdrawn EP0054909A3 (en) 1980-12-18 1981-12-16 9-halo-8-hydroxy-4-methyl-4-nonenoic acids, derivatives thereof and a process for their preparation

Country Status (7)

Country Link
EP (1) EP0054909A3 (en)
AU (1) AU7792481A (en)
DK (1) DK554681A (en)
ES (1) ES508129A1 (en)
FI (1) FI814008L (en)
IL (1) IL64561A0 (en)
NO (1) NO814333L (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1317624A (en) * 1969-09-22 1973-05-23 Zoecon Corp Hydroxy alkenoic acids derivatives thereof and their use in the control of insects
GB1380734A (en) * 1971-01-20 1975-01-15 Hoffmann La Roche Polyene compounds and their manufacture

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1317624A (en) * 1969-09-22 1973-05-23 Zoecon Corp Hydroxy alkenoic acids derivatives thereof and their use in the control of insects
GB1380734A (en) * 1971-01-20 1975-01-15 Hoffmann La Roche Polyene compounds and their manufacture

Also Published As

Publication number Publication date
NO814333L (en) 1982-06-21
DK554681A (en) 1982-06-19
EP0054909A2 (en) 1982-06-30
ES508129A1 (en) 1982-11-01
AU7792481A (en) 1982-06-24
FI814008L (en) 1982-06-19
IL64561A0 (en) 1982-03-31

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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AK Designated contracting states

Designated state(s): AT BE CH DE FR GB IT NL SE

PUAL Search report despatched

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STAA Information on the status of an ep patent application or granted ep patent

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18W Application withdrawn

Withdrawal date: 19821005

RIN1 Information on inventor provided before grant (corrected)

Inventor name: TAKAYANAGI, HISAO

Inventor name: MORITA, YOSHIHARU