EP0024924A3 - Sydnonimines, their preparation and pharmaceutical compositions containing them - Google Patents

Sydnonimines, their preparation and pharmaceutical compositions containing them Download PDF

Info

Publication number
EP0024924A3
EP0024924A3 EP80302983A EP80302983A EP0024924A3 EP 0024924 A3 EP0024924 A3 EP 0024924A3 EP 80302983 A EP80302983 A EP 80302983A EP 80302983 A EP80302983 A EP 80302983A EP 0024924 A3 EP0024924 A3 EP 0024924A3
Authority
EP
European Patent Office
Prior art keywords
sydnonimines
preparation
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP80302983A
Other versions
EP0024924B1 (en
EP0024924A2 (en
Inventor
Reinhardt Peter Stein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Priority to AT80302983T priority Critical patent/ATE4540T1/en
Publication of EP0024924A2 publication Critical patent/EP0024924A2/en
Publication of EP0024924A3 publication Critical patent/EP0024924A3/en
Application granted granted Critical
Publication of EP0024924B1 publication Critical patent/EP0024924B1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/04—1,2,3-Oxadiazoles; Hydrogenated 1,2,3-oxadiazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
EP80302983A 1979-08-31 1980-08-28 Sydnonimines, their preparation and pharmaceutical compositions containing them Expired EP0024924B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT80302983T ATE4540T1 (en) 1979-08-31 1980-08-28 SYDNONIMINE, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US7160679A 1979-08-31 1979-08-31
US71606 1979-08-31
US06/171,423 US4277609A (en) 1979-08-31 1980-07-29 Sydnone imines
US171423 1980-07-29

Publications (3)

Publication Number Publication Date
EP0024924A2 EP0024924A2 (en) 1981-03-11
EP0024924A3 true EP0024924A3 (en) 1981-03-18
EP0024924B1 EP0024924B1 (en) 1983-08-31

Family

ID=26752423

Family Applications (1)

Application Number Title Priority Date Filing Date
EP80302983A Expired EP0024924B1 (en) 1979-08-31 1980-08-28 Sydnonimines, their preparation and pharmaceutical compositions containing them

Country Status (10)

Country Link
US (1) US4277609A (en)
EP (1) EP0024924B1 (en)
JP (1) JPS56501088A (en)
AU (1) AU533086B2 (en)
CA (1) CA1145756A (en)
DE (1) DE3064707D1 (en)
DK (1) DK190781A (en)
GB (1) GB2058064B (en)
IE (1) IE50230B1 (en)
WO (1) WO1981000567A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4446322A (en) * 1980-07-29 1984-05-01 American Home Products Corporation Hydroxyl protected 3-(2-hydroxy-2-phenylethyl)-N-[(phenylamino)carbonyl]sydnone imine intermediates
US4371539A (en) * 1981-04-27 1983-02-01 American Home Products Corporation CNS Stimulants
DE3526068A1 (en) * 1985-07-20 1987-01-22 Cassella Ag SUBSTITUTED 3-AMINO-SYDNONIMINE, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME
DE3732174A1 (en) * 1987-09-24 1989-04-06 Cassella Ag SUBSTITUTED 3-AMINO-DYNONOMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE
US8691853B2 (en) 2007-03-14 2014-04-08 Caliper Life Sciences, Inc. Method of using dopamine reuptake inhibitors and their analogs for treating autoimmune conditions and delaying or preventing autoimmune related pathologic progressions
ES2582660T3 (en) 2007-03-14 2016-09-14 Caliper Life Sciences, Inc. Sidnonimines - specific dopamine reuptake inhibitors and their use in the treatment of dopamine-related disorders
US9119843B2 (en) 2009-12-04 2015-09-01 Caliper Life Sciences, Inc. Method of using dopamine reuptake inhibitors and their analogs for treating diabetes symptoms and delaying or preventing diabetes-associated pathologic conditions
JP6605447B2 (en) * 2013-03-15 2019-11-13 メリオール・ファーマスーティカルズ・ツー・リミテッド・ライアビリティー・カンパニー Methods of treating dyskinesia and related disorders

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2372160A1 (en) * 1976-11-25 1978-06-23 Inst Im Ordzhonikidze Psycho-stimulant (N)-acyl-3-phenyl or phenethyl-sydnone imine derivs. - prepd. by reacting (N)-nitroso-amino-acetonitrile derivs. with an acylating agent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE618822A (en) * 1961-06-13
SU222370A1 (en) 1966-09-21 1973-05-15 Р. А. Альтшуллер, Д. Машковский, Л. Е. Холодов , В. Г. Яшунский METHOD OF OBTAINING N-ARILKARBAMOILSIDNONYMINS
DE2028880C3 (en) 1970-06-11 1979-03-08 Vsesojuznyj Nautschno-Issledovatelskij Chimiko-Farmacevtitscheskij Institut Imeni Sergo Ordschonikidze, Moskau N-Phenylcarbamoyl-3- (ßphenylisopropyl) sydnonunine, process for its preparation and pharmaceuticals

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2372160A1 (en) * 1976-11-25 1978-06-23 Inst Im Ordzhonikidze Psycho-stimulant (N)-acyl-3-phenyl or phenethyl-sydnone imine derivs. - prepd. by reacting (N)-nitroso-amino-acetonitrile derivs. with an acylating agent

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF MEDICINAL CHEMISTRY, vol 14, no. 10, October 1971, Washington, USA; V.G. YASHUNSKII et al.: "Synthesis and pharmacological effects of some alkyl-, aryl-, and aralkylosydnonimines", pages 1013-1015 *

Also Published As

Publication number Publication date
JPS56501088A (en) 1981-08-06
EP0024924B1 (en) 1983-08-31
AU6179980A (en) 1981-03-05
WO1981000567A1 (en) 1981-03-05
EP0024924A2 (en) 1981-03-11
US4277609A (en) 1981-07-07
DK190781A (en) 1981-04-29
CA1145756A (en) 1983-05-03
DE3064707D1 (en) 1983-10-06
IE801809L (en) 1981-02-28
AU533086B2 (en) 1983-10-27
GB2058064A (en) 1981-04-08
IE50230B1 (en) 1986-03-05
GB2058064B (en) 1983-05-18

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